Douxo S3 CALM Soothing Itchy, Hydrated Skin Dog & Cat Shampoo

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Your pet will love getting a little extra TLC for her skin at bath time with Douxo S3 CALM Dog & Cat Shampoo. This shampoo is formulated with skin-soothing ingredients like ophytrium, which helps strengthen the skin barrier. It helps restore the balance of protective microbes and soothe that annoying itchy, irritated skin. It’s made without soaps, sulfates, parabens, dyes and nanoparticles––just safe skincare goodness! As a bonus, it even moisturizes and detangles the fur, leaving behind a silky, shiny coat and soothed skin.

Key Benefits
  • Shampoo for dogs and cats that helps soothe irritated skin.
  • Helps restore the balance of protective microbes.
  • Contains ophytrium, a natural ingredient that helps strengthen the skin barrier.
  • Made without soaps or sulfates.
  • Free of parabens, dyes and nanoparticles.

For external use on dogs or cats only; avoid contact with eyes. If eye contact occurs, rinse thoroughly and consult your veterinarian. If skin irritation occurs or increases, discontinue use and consult with your veterinarian. Wash hands after using.
If your furry friend is using a topical flea and tick treatment, please remember to follow the bathing instructions on the flea and tick packaging. Each treatment works differently and may require different wait times before water exposure.

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  • Item Number
  • Lifestage
  • Breed Size
    Small Breeds, Medium Breeds, Large Breeds
  • Grooming Feature
  • Product Form

Ophytrium, Chlorhexidine

Recommended Dosage

Use as recommended by your veterinarian. Wet the fur with cool water from the neck down. Using 1 pump for every 4 lbs, gently massage shampoo onto skin abnormalities to reach the skin. Repeat until entire body is lightly coated with shampoo and leave on for 10 minutes. Rinse thoroughly with cool water. Shampoo amount can be doubled for dogs or cats with long and/or thick fur.

Apply, lather and rinse.

Soothing Skincare for Pets

DOUXO S3 features Ophytrium, a purified natural ingredient that acts in three key ways to encourage healthy and comfortable skin. Ophytrium helps support supple and hydrated skin to reinforce the skin’s physical barrier, and it helps nurture healthy microbial skin flora, too. It also helps soothe red, itchy and irritated skin.

Product Grouping
Dog Scratching

Targeted Skin Care

DOUXO S3 comes in four formulations to help support common pet skin concerns. DOUXO S3 CALM helps soothe itchy, irritated allergic skin, while antiseptic and antifungal DOUXO S3 PYO helps control skin infections. There is also DOUXO S3 SEB, which offers dandruff control for greasy, flaky or dry skin, and DOUXO S3 CARE, which is an ultra-gentle formula designed for regular use.

Formulated by Vets

Products in the DOUXO S3 line are formulated by veterinary dermatologists and tested using an enhanced protocol to ensure safety for pets and the people who care for them. The formulas are easy to use, too. Simply shampoo once to remove dirt, debris and allergens, then use the mousse every 2-3 days afterward for three weeks.

Dog in Bath
Cat Bath

No Controversial Ingredients

DOUXO S3 formulas are made without soap, sulfates, parabens, colorants, phthalates or nanoparticles. They feature a hypoallergenic “summertime” coconut and vanilla fragrance and an adjusted pH optimized specifically for your pet’s skin. The easy to use bottles make application a breeze, too.

About DOUXO S3

DOUXO S3 is a line of non-prescription topical pet skincare products designed to nourish and nurture healthy, problem-free skin. The formulas contain Ophytrium, a proprietary active ingredient that helps support the protective skin barrier. Veterinarian-recommended S3 products are made without potentially irritating soap, sulfates, parabens, colorants, phthalates or nanoparticles and are clinically tested for safety.


Rating: 3.7 of 5 stars 4 Reviews 4 Reviews 3.8 out of 5 Stars

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75% Recommend

75% of reviewersrecommend this product

Rating: 3.7 of 5 stars 3.8 / 5

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4 Reviews

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  • 5 out of 5 stars

    Wonderful coat

    By cacklein on Apr 29, 2021

    I have my cockerpoo's coat cut short for the hot summer months which makes her skin susceptible to skin rashes from the chemicals used on the lawns and general allergies. I tried this shampoo and it left her coat and skin hydrated and looking the best ever. She has stopped her itching and I like that It is not heavily scented.. It may be expensive but a little goes a long way and it is now my go - to shampoo for her. Her comfort is my goal!

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  • 2 out of 5 stars

    not same formulation

    By Becky on Apr 14, 2021

    This shampoo used to be amazing. It was clear, scent free and was wonderful for my dachshund’s sensitive skin. They changed the formula. It’s now milky white in color and has an odd “coconut” smell. Haven’t used on my dog because I can’t stand the smell.

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  • 5 out of 5 stars

    Great product

    By MSLR on Feb 22, 2021

    This was recommended by my vet. My Maltese has very sensitive skin and this shampoo helps with irritated skin due to allergies. Works great, helps the itching. I use the lotion in between shampoos.

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  • 3 out of 5 stars

    itchy dog skin

    By threeHappyDogs on Mar 11, 2021

    I bought 4 dif kinds from this company, we will give it some time to see IF they work for itchy dogs skin, lets hope it was kind of expensive for small bottles.

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