Fluoxetine HCl Compounded Transdermal for Cats

By Fluoxetine HCl Compounded
Rated 4.4286 out of 5 stars
Prescription Item


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$57.75Chewy Price
$54.86Autoship Price
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Usually arrives in 3-5 days
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Medications ship separately. Delivery times may vary.

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About This Item


Fluoxetine HCl is a selective serotonin reuptake inhibitor (SSRI) that may be prescribed for behavior issues, obsessive compulsive disorder, anxiety, digestive issues, and inflammatory bowel disease. Fluoxetine HCl Compounded transdermal comes in a Topi-CLICK Micro transdermal pen to more accurately administer medications made specifically for your pet.

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ReviewsWrite a Review

Rated 4.4286 out of 5 stars
42 Ratings
Would recommend to a friend

42 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.
Rated 5 out of 5 stars
By Josh on Sep 11, 2023

To begin with, this is a prescription product. I’m writing this review for anyone who’s on the fence about their vet’s recommendation. Gimli has always been a nervous cat. He’s easily the most skittish of our colony, and has a bad habit of spraying when he’s feeling particularly anxious. My vet prescribed Fluoxetine, and when we could get him to take it, it helped tremendously. The problem was the pills and the liquid. Trying to pill this cat was an absolute nightmare. The transdermal solution, however, is a substantial upgrade. While he still isn’t a fan of it, administering it isn’t anywhere near as much of a problem. It works really well, and I’m really glad that my vet suggested it. When you pair that with how efficient Chewy’s pharmacy is, it’s fantastic.

Rated 5 out of 5 stars
By AK on Aug 2, 2023

I have a cat who recently started fighting with my other cat after they've been living together for 6yrs. Around the same time she also started urinating on nearly everything that was on the ground. I tried everything I could think of like changing the litter, adding more litter boxes, etc, and was close to rehoming her. After ruling out illness with our vet, they prescribed fluoxetine and said the transdermal application would be the easiest. We're a few weeks in and I'm seeing a huge improvement. I'm realizing that my cat no longer tries to escape outside or bite at her claw caps. She hasn't urinated outside the litter box since starting meds and he's been nicer to the other cat, though she has hisses a couple times. I wasn't expecting to see a turnaround for several weeks and I'm pleasantly surprised. It's very easy to apply. You just click it the number of times it says on the label and rub it in your cat's ear.

Rated 5 out of 5 stars
By onyx on Jul 21, 2023

My cat onyx is very skittish, to the point t he was constantly getting urine infections. The vet started him on pill form, it worked wonders, but he hated the pulls. It got to the point I couldn't catch him to give it. Pull pockets didn't work, crushing it in his food didn't work. The vet suggested this. Oh my gosh, so much better. Yes he doesn't like me rubbing it in his ears, but so much easier. Since starting the Prozac we've had no additional infections and he actually comes out to eat, lays in the bed with us. So much more sociable. Plus chewy is about $10 for the pen than buying it from the vet.

Rated 5 out of 5 stars
By Amy on Jun 29, 2023

Now living her best life

My himalayan, Phyllis, has always been skiddish around people since she was a baby. Whenever someone would come over she would hide under the bed. I am in the process of moving in with my boyfriend. He has a dog and I have one as well that Phyllis hates. I slowly have been introducing her to the dogs and the house, but she wouldn't come out from under my boyfriends bed. I decided to get her on meds at least a month before we officially moved in so it would have time to get into her system. This has worked wonders!!! She now hangs out with all of us. She likes to sleep on the seat cushions in the dining area because it's full of windows. The dogs are constantly running around the table, right next to her, playing, barking and growling at each other. She doesn't move or care. That's a huge improvement. She's finally living her life and I'm so grateful. She also tolerates me putting the cream in her ear. She takes a small dose of one click.

Rated 3 out of 5 stars
By Barb on May 5, 2023


So since I adopted Romeo, he has been in his own room and seems to be very terrified of everything. Some inhuman person dumped him in the parking lot and I don’t know the rest of the story and neither does anyone else I know that he is depressed, and I believe that, even though somebody dumped him he might be missing those people. The doctor and I decided to put him on this medication. I thought transdermal would be the best to put his ears because I didn’t know if he would take by the mouth. However he is terrified of me touching his ears too , so every day I have to figure out a way to get the medicine in. It’s been about three weeks since he’s on this medicine and so far there hasn’t been a positive change. I am hoping that this will change soon.

Rated 5 out of 5 stars
By Monica on Jun 20, 2023

Chilled my cat out

I usually don't recommend drugging animals, but I've got a super-aggressive cat who has bitten several people badly (we're talking hospital visits). He now takes kitty Prozac 2x/day and has chilled out a LOT. Chewy got the Rx to us quickly and without hassle.

Rated 5 out of 5 stars
By Sandra on Apr 20, 2023

Life saver. Literally.

I have a very aggressive cat with PTSD and high anxiety. When she feels cornered or trapped, like say when you're trying to force a pill down her throat, she gets triggered and will attempt to murder anything with a pulse in sight. We have to wear kevlar protective clothing when doing things to her that she finds triggering. She has sent me to the ER. Not a joke. I care for a tiny, mentally ill mountain lion. This makes giving her her much needed meds a breeze. It took some time to get her used to the sensation on her ear, and for a few months would run at the sound of the click, now she doesn't mind it at all. They just have to learn that this unknown thing isn't so dangerous afterall.

Rated 5 out of 5 stars
By Leroy on Sep 27, 2023

Great product

Love the product it works on the cat. I have a monthly prescription.

Rated 1 out of 5 stars
By lo on May 24, 2023

Horrible Results

I switched ears daily, yet in the matter of a week my cat's ears became raw and red and bleeding. They did my appear scratched. They looked like open sores that had suddenly developed.

Rated 1 out of 5 stars
By Lexi on Mar 7, 2023

Made Things Worse

My very anxious cat has been spraying and my vet recommended this to help. He is terrified of being approached or picked up so I have to wait for him to come to me, hold him, and then give him the treatment. He flinches when the pen clicks and when I'm done, he runs off and rubs it off his ear with his paws. He's been spraying even more now since using this and I'm at a loss, he's destroying everything and I guess I'll have to try the pill form to see if that works.