HILL'S PRESCRIPTION DIET z/d Skin/Food Sensitivities Original Flavor Dry Dog Food, 25-lb bag - Chewy.com

Hill's Prescription Diet z/d Skin/Food Sensitivities Original Flavor Dry Dog Food

By Hill's Prescription Diet
Rated 4.4523 out of 5 stars
Veterinary Diet Item

Spend $100 On Select Prescription Food/Treats, Get a $15 eGift Card

$123.99Chewy Price
$117.79Autoship Price
(Save an extra 5%)

Why Autoship?

  • Save 5% on all future Autoship orders
  • Set your schedule based on your pet's needs
  • No fees, no commitments - skip, change or cancel anytime.
This item requires vet authorization.

In Stock
FREE 1-3 day shipping

About This Item


  • Helps improve your dog’s digestion and stool quality with highly hydrolyzed protein.
  • Helps eliminate food-related causes of skin irritation and results in a visible improvement of the skin and coat.
  • Helps maintain a healthy skin barrier and enriched with essential fatty acid.
  • Clinically proven antioxidants are added for optimal health benefits, plus it’s developed with a single carbohydrate source—cornstarch.
  • Skin/Food Sensitivities recipe has not changed—it offers the same great taste and benefits as it did prior to the introduction of the S+OXSHIELD seal of confidence.

See More

Nutritional Information

Feeding Instructions


Play Video: Learn More About Hill's Prescription Diet From Our Team of Experts
Learn More About Hill's Prescription Diet From Our Team of Experts

About Hill's Prescription Diet Foods for Skin / Food Sensitivities

Improving Lives Together

Groundbreaking Nutrition for Sensitive Dogs

Dogs with skin and coat conditions or food sensitivities can benefit from Hill's Prescription Diet z/d and d/d foods. Prescription Diet d/d has limited ingredient nutrition and a single intact animal protein. The Prescription Diet z/d food features a highly hydrolyzed protein and a single carbohydrate source to minimize the risk of allergic reactions. Many pet parents discover that simply eating the right food helps eliminate food-related causes of skin irritation and helps avoid reactions to food.

Clinical Nutrition

With Hill's, it's not just high-quality ingredients that count. Their focus is on the proper balance of nutrients in every recipe. So Hill's has developed foods that are designed to help pets with specific health conditions, providing the right nutrients to support their health. Hill's alliance with veterinarians puts them in a unique position find a nutrition recommendation for your pet no matter what health issue your pet is facing.

Formulated by Veterinarians

Hill's Prescription Diet started with a veterinarian's belief that some health issues could be managed through nutrition. What began as a theory has now been proven through extensive research by a team of over 220 vets, PhD nutritionists and food scientists. The results can be seen in Hill's Prescription Diet therapeutic pet foods.

Meeting the Highest Standards

Providing a food that delivers exactly what it says it does is Hill's number one priority, in fact, they perform over five million safety and quality checks every year. They've established relationships with trusted suppliers and will only accept ingredients that meet stringent standards.

The Taste Factor

You might know that Hill's Prescription Diet is good for your pet, but she's only concerned with the taste. Even though they place a heavy emphasis on nutrition, Hill's hasn't forgotten about palatability. Savory ingredients are combined to produce foods with enticing aromas, textures, and shapes that your pet can't resist.

Find the Right Formula

Talk to your veterinarian about the right formula for your pet.

z/d Skin/Food Sensitivities


Key Nutrients

  • Highly hydrolyzed animal protein
  • Single purified carbohydrate source
  • High levels of vitamin E
  • Natural fiber
  • Essential fatty acid enriched
  • Clinically proven antioxidants

Health Benefits

  • Visible skin and coat improvement in 30 days
  • Promotes healthy skin barrier
  • Helps support a healthy immune system
  • Clinically proven to help normalize stool

d/d Skin/Food Sensitivities

Potato & Venison

Potato & Duck

Potato & Salmon

Key Nutrients

  • Limited ingredient nutrition with single intact animal protein
  • No soy protein or gluten
  • High levels of omega-3 and 6
  • Clinically proven antioxidants

Health Benefits

  • Results you can see in the skin and coat
  • Helps maintain a healthy skin barrier
  • Helps improve digestion and stool quality
  • Supports a healthy immune system

Derm Defense


Key Nutrients

  • With proprietary complex of bioactives and phytonutrients
  • High levels of omega-3 and 6 fatty acids
  • Clinically proven antioxidants, including vitamin E
  • No corn, chicken or by-product meal, artificial colors, flavors or preservatives

Health Benefits

  • Helps strengthen skin barrier
  • Drives healthy skin from within
  • Formulated to help soothe and nourish skin and coat
  • Helps skin to recover naturally
  • Holistic long-term solution supporting healthy immune system

About Hill's Prescription Diet

Hill's mission is to help enrich and lengthen the special relationships between people and their pet. Their Prescription Diet product line delivers clinically proven nutrition that supports common pet health concerns, from digestive and urinary health to aging and weight management.
Shop Hill's Prescription Diet

Questions & Answers

38 Customer Questions

How many cups is in a 25lb bag?
Answer by ChewyJun 09, 2018
There are approximately 32 cups of kibble in the 8 pound bag, 70 cups of kibble in the 17.6 pound bag, and 100 cups in the 25 pound bag.

Does it help ear yeast infection with growths within the ears in English Springer Spaniels?
Answer by ChewyJun 23, 2018
We would recommend consulting with your veterenarian due to the medical condition, it may require further medical treatment or medicine.

How many calories are in a cup of hill prescription zd dry and wet food?
Answer by ChewyMay 06, 2020
This formula contains approximately 354 calories per cup.

If the z/d is not Gluten Free (It sounds like it has wheat in it?) That defeats the special diet needed for my pup.
Answer by ChewySep 30, 2021
This food contains no gluten, soy protein, lactose, and is not artificially colored, flavored or preserved.

ReviewsWrite a Review

Rated 4.4523 out of 5 stars
953 Ratings
Would recommend to a friend

953 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.
Rated 1 out of 5 stars
By Drew on May 5, 2023

Did nothing productive for my dog's allergies

My pit bull had a bad allergy flair up and rash breakout that my vet attested to it likely being his food and him having a protein allergy. So I got a script for this and after feeding it to him for 8 weeks (and only this, used as treats too and he doesn't ever get fed any table scraps anyway) and spending a fortune it has done absolutely nothing to reduce his itching, rashes or licking issues. I ordered him an allergy test that we are still waiting on the results for and I would strongly advise going that route first before trying this seemingly rip-off food. It is much more productive to isolate the trigger than to just guess and spend an outrageous amount of money that doesn't even fix the issue, it just masks it. You need to KNOW what your dog is allergic to, it can be just about anything and so random, so you can avoid those products. I'm very disappointed in my vet for recommending this without offering any other alternatives first. I should have been more intuitive but I was in a hurry to try and help my dog out because he had to be miserable with all these skin issues.

Rated 5 out of 5 stars
By mom2murphy on Apr 28, 2023

my lab pup finally has an appetite!

We got our lab pup at 8 weeks and expected a standard, food driven dog. We gave him the food our breeder used and from the very beginning he had a weird relationship with food and water. Having to be coxed into eating. I bought canned foods to encourage eating, but it was still hit or miss. At 8 months he had already been to the vet twice for ear/eye infections. We told the vet about the lack of appetite and lethargy. He suggested a potential allergy. Rather than guess at what the allergy was, we had him tested…he is allergic to almost every basic ingredient in dog foods. So after doing a ton of research I found this product. He is now 100% on this product and he is happily eating regular meals every day. It’s pricey, but it is worth it to finally have our pup eating the way he should!

Rated 1 out of 5 stars
By Tracy on May 21, 2023

Chicken food

My dog has terrible allergies so my vet recommended this food. It caused my dogs allergies to worsen to a severe skin infection and when I looked at the ingredients I saw chicken! Chicken is a common allergen so I am not sure why they are making a prescription food with it. Never again would I ever feed this to my dog.

Rated 5 out of 5 stars
By MaddieA on Apr 1, 2023

Only food our dog can have

Our vet says this is the only food we can give our dog due to her liver and bowel inflammation. Our girl loves the food, and to see her "peanut butter box" arrive, but we can't get through the 17lb bag before it gets stale and she will refuse to eat the last 25% of it. We end up throwing it out, it is way too expensive for that. Just started buying the 8lb bags, but they are much more expensive per pound. No way around it unfortunately. Our dog likes the smaller kibbles, easier to eat for a senior Labrador. The food doesn't smell as bad as some of the other prescription foods and it's helped her feel better. The Hypo Treats, which are also the Z/D diet are a favorite! We did try another premium well-known prescription of the same type, it was refused by our dog.

Rated 5 out of 5 stars
By Jingram13 on May 26, 2023

A New Favorite

This food is amazing! My pup, Dakota, just wasn’t himself for the last 2 months. Refusing meals/treats and leaving behind half eaten bowls. Since switching to the Hill’s z/d, his appetite is back in full force. This formula is a new favorite in our home and worth the high price!

Rated 5 out of 5 stars
By BB on May 21, 2023

Finally found the right food!

My berniedoodle has a lot of allergies and is a very picky eater. Finally after many attempts at food and a lot of money wasted, we found the food he will eat! Did I mention I absolutely love this company! If you have a picky eater with allergies, give this a try!

Rated 4 out of 5 stars
By ELIZABETH on May 17, 2023

vet contact still a problem

The price was great, the incentives were great, but (again) I had trouble in the conversation between my vet and Chewey. Chewey sent email saying "we've tried several times to contact your vet" and my vet says "we've received no request from Chewey.

Rated 2 out of 5 stars
By Brittany on Apr 20, 2023

Formulation change?

My dog was on this food for about 4 years, it seems that this past 6 months the formulation has changed and he doesn't want to eat it no matter what I do. I tried 2 different bags and he will only eat about 20 pebbles and walk away from his food. I thought he was sick, but after tests and a week of not wanting the food we switched to a different brand and he is eating again.

Rated 1 out of 5 stars
By Yellowdog on Mar 30, 2023

Lab refused to eat.

The vet put our Lab on this food for dermatitis. Unfortunately, our Lab refused to eat it and actually spit it out! Looking at the ingredients I can't say I blame him. Who wants to eat cornstarch and cellulose? The food got very slimy when wet - even with just slobber with no water and when put in water swelled to more than twice it size!

Rated 5 out of 5 stars
By Sunday on May 14, 2023

This food sensitities is helping quite a bit with our Newfoundland dog. She no longer has hot spots and has quit scratching constantly.