Hill's Prescription Diet Gastrointestinal Biome Chicken Flavor Dry Dog Food

By Hill's Prescription Diet
Rated 4.8425 out of 5 stars
Veterinary Diet Item
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Hill's Prescription Diet Gastrointestinal Biome Chicken Flavor Dry Dog Food, 27.5-lb bag slide 1 of 11
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$116.99Chewy Price
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About This Item

  • This prescription formula is designed to support the bacteria in your dog's gut.
  • Utilizes Hill's ActivBiome Technology—a mixture of active fibers that may help improve regularity.
  • Encourages the release of postbiotics to support the GI tract and help break down food.
  • Works to promote regular, healthy stool and reduce the risk of future episodes.
  • Formulated by Hill's trusted nutritionists and veterinarians.
Play Video: Learn More About Hill's Prescription Diet From Our Team of Experts
Learn More About Hill's Prescription Diet From Our Team of Experts

About Hill's Prescription Diet GI Biome Food for Dogs

Hill’s GI Biome Diet

Hill’s Prescription Diet Gastrointestinal Biome dog food takes a different approach to digestive care. Each formula uses a specific blend of active fibers, known as ActivBiome+, to help your dog’s stomach break down food more efficiently and promote healthier stools and regularity. It also contains Hill’s S+OX Shield ingredients, formulated to promote urinary health.

Activate the Gut Microbiome

When it comes to canine digestive health, the balance between good and bad bacteria is key. Promoting the growth of good bacteria helps keep problematic bacteria in check and supports ongoing digestive well-being.

Know the Signs of Digestive Issues

If you notice vomiting, diarrhea or soft stools, straining, stomach gurgling, flatulence, appetite changes, lethargy or depression in your dog, it may be from digestive trouble. See your vet for more insight and see if changing foods can help.

Risk Factors

Many things can trigger digestive issues in your pup, including food sensitivities, inflammation and bacterial, viral or parasite infections. Your vet can help determine what’s causing the trouble and figure out how diet can play a role.

Veterinarian Recommended

Vets know what’s best for their furry patients, so knowing that they place their trust in Hill’s can give you peace of mind.

About Hill's Pet Nutrition

For more than 70 years, Hill's Pet Nutrition has helped enrich and lengthen the special relationship between people and their pets by putting their passion for the health and happiness of animals into everything they do. They even partner with shelters to provide Hill's food to more than 9 million shelter pets.
Shop Hill’s Pet Nutrition

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Top IngredientsChicken, Cracked Pearled Barley, Brewers Rice...Whole Grain Wheat, Whole Grain Corn, Chicken Meal...New: Brewers Rice, Whole Grain Corn, Chicken Meal...Brown Rice, Brewers Rice, Chicken Fat...Brown Rice, Brewers Rice, Pork Fat...
Breed SizeSmall Breeds, Medium Breeds, Large Breeds...Small Breeds, Medium Breeds, Large Breeds...Small Breeds, Medium Breeds, Large Breeds...Small Breeds, Medium Breeds, Large Breeds...Small Breeds, Medium Breeds, Large Breeds...
Special DietPea-Free, Veterinary Diet, Sensitive Digestion, With GrainVeterinary Diet, Weight Control, With GrainVeterinary Diet, Sensitive Digestion, With GrainPea-Free, Veterinary Diet, With GrainPea-Free, Veterinary Diet, With Grain
Food FlavorChicken, PoultryChicken, PoultryChicken, PoultryLamb, MeatChicken, Poultry
Health FeatureDigestive HealthWeight ManagementDigestive HealthKidney CareKidney Care

Questions & Answers

16 Customer Questions

Is this dog food made in the United States? Where are the ingredients sourced?
Answer by ChewyMar 15, 2021
Hills is manufactured in the United States. We source raw materials only from countries where there are reliable safety procedures in place, primarily in the United States, Japan, Canada, New Zealand, Australia and several European countries.

Asking for Great Dane breed - do you have information about the Calcium/ Phosphorus ratio? I didn't see it in the Guaranteed Analysis tab - thanks in advance
Answer by ChewyOct 16, 2019
This dry dog food formula has a calcium content of 1.18% and a phosphorus content of 0.68% on an dry matter basis.

Can this be used for puppies?
Answer by ChewyNov 29, 2019
Animal feeding tests using AAFCO procedures substantiate that Hill's Prescription Diet Gastrointestinal Biome Canine provides complete and balanced nutrition for maintenance of adult dogs. It would not be appropriate for puppies. Due to your pets specific health concern, we recommend consulting your Veterinarian to see what would be the safest fit for your pets current treatment plan.

Does this food cause extra thirst?
Answer by ChewyNov 23, 2020
The manufacturer does not currently have any records on side effects like extra thirst. We recommend consulting your veterinarian if you are unsure about possible side effects, as they have an entirely different industry insight, and they can give you a second opinion based on both professional experience and research.

ReviewsWrite a Review

Rated 4.8425 out of 5 stars
457 Reviews
Would recommend to a friend

457 Customer Reviews

Rated 5 out of 5 stars
By ChewyCustomer on Sep 21, 2022


I have only been using this just under 2 weeks, but it started working right away and is still working magic. My dog has chronic diarrhea. He'll be fine for 6 or 8 months and then not fine for several months, possibly triggered by him eating things in the yard he shouldn't. A couple rounds of metronidazole usually works, but that's not healthy on a repeated basis. My vet suggested this food and after reading reviews, I decided to try this instead of the GI food i usually get. It really does work!! I'm going to try to work in some of his regular food 50/50, like another reviewer mentioned, but for now I'm just so happy with his picture perfect poops!

Rated 5 out of 5 stars
By Lydia on Sep 11, 2022

Great food!

my 10 month old miniature dachshund was struggling with diarrhea issues for the longest time. he’d go on medication for it but as soon as he finished the dose, the diarrhea would start again. he was previously on the purina pro plan puppy lamb and rice dry food, and i have nothing against that! he loved it for the longest time! however, around the same time as the bathroom issues started, he began to not want to eat his food. i guess it just wasn’t satisfying him anymore. so after a few vet visits, his veterinarian recommended the hills prescription gastrointestinal biome diet! safe to say this helped solve his issue!!! my little guy has a sensitive stomach!! and this food cleared his stool right up! He also suffered with anal gland issues, which was most likely caused from the soft stool and not being able to express those with a solid stool. I STRONGLY recommend this food to other dog owners who may be struggling with the same issue or who just want a bland diet for their pups!

Rated 5 out of 5 stars
By Micki on Sep 23, 2022

Great product

It's true - within one day of switching to Gastrointestinal Biome full strength, my girl Rosie had normal poop. So far, it's the only food that has worked for her. It also seems that in spite of the recommendation that no other food should be introduced, regular dog treats and a little bit of cheese seem fine.

Rated 5 out of 5 stars
By Anitazo on Aug 28, 2022

Agree it’s miracle food

was worried because of the concerning things other pet parents said about Hills Science but my vet recommended this formula when my French Bulldog was having the worst stools. Nothing else worked except for THIS. Whenever we try to wean off of it symptoms return. Clearly this works with his body. He does well with a 50 50 blend of this food with another brand and our vet is happy with that. We are grateful for this food!

Rated 5 out of 5 stars
By Wheels on Sep 23, 2022

Works great!

This worked almost immediately to settle my dog's stomach. We first tested for parasites, and there were none. Still his extremely loose stool persisted. After less than 24 hours, his stool was great! We finished the small bag, and he's now back on his usual food.

Rated 5 out of 5 stars
By dogmom1990 on Jul 28, 2022

Miracle Food!

My 8 year old boxer mix has had issues with loose stools for years. After a particularly terrible case of colitis the vet put her on Purina EN canned food but the diarrhea continued so they suggested this as the holy grail food for dogs with diarrhea. They were so right because it’s been a night and day difference. As soon as she was on the majority of this food versus the Purina EN (I switched her slowly to be safe) her stool firmed up. As an added bonus she’s now drinking more water than she was before which was an issue previously. This food seems to have her feeling better all over. It is very expensive but it is well worth the money to stop the diarrhea. She sometimes acts picky about eating it but I find that just a few pieces of freeze dried chicken liver treats crumbled over it does the trick and doesn’t seem to cause any digestive upset.

Rated 5 out of 5 stars
By RockyCuddleBear on Aug 24, 2022

Like a miracle

My dog has been to so many vets and tried so many prescription diets, supplements, you name it, and never got any better. By the third day on Gastrointestinal Biome he had consistently firm, good, poops. His chronic diarrhea, stomach pain, and lack of appetite are all resolved and I’m just so happy to see him finally feeling good.

Rated 5 out of 5 stars
By Malky on Aug 24, 2022

Tummy trouble getting better!

I bought this food because my senior Beagle started having loose stools after eating her long-time healthy weight diet, the same food my son feeds his dog who is much younger and had similar symptoms. For the most part, it's helping. Mine did have a day of loose stools about a month in, but she's already doing better. She loves the taste, too, and hasn't missed a meal!

Rated 5 out of 5 stars
By Susytg on Jul 25, 2022

Life changing nutrition for my senior Newf

My senior newfy girl's digestion changed as she got older. She could no longer enjoy her regular food without gastro problems. We tried changing her food, every other week of boiled chicken and rice, Metronidazole, Tylan, prebiotics, probiotics, you name it we tried it - everything under the sun. Our reg vet suggested we see an IM specialist and they recommended this food. It was lifechanging. Her poops are small and firm, no more mucus in her stools. Leaves no residue when we pick it up.. She's our happy girl again. It is expensive, but our furkids are worth it.

Rated 5 out of 5 stars
By DougwithMateo on Jul 13, 2022

Absolute Digestive Turnaround within 24 Hours

This was recommended for out 6-month Golden mix who had been having some semi-serious digestive problems for a few months, mostly in the form of very soft stools. That's a problem on a number of levels in terms of nutritional absorption, and after he tested negative for parasites (twice) the vet suggested this food. Also note that we'd tried things like plain chicken and rice with no real improvement, so the hope was that this food might be a better fit. Well, "better" doesn't even fit, because it was a 100% improvement in less than 24 hours! By the evening of the first day his stool was already just about back to normal, and by the next morning it was completely there! So, though it is obviously a bit on the expensive side, in this case it's absolutely worth it. It just works, simple as that.