Hill's Prescription Diet Gastrointestinal Biome Chicken Flavor Dry Dog Food

By Hill's Prescription Diet
Rated 4.7973 out of 5 stars
Veterinary Diet Item


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$127.99Chewy Price
$121.59Autoship Price
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About This Item


  • This prescription formula is designed to support the bacteria in your dog's gut.
  • Utilizes Hill's ActivBiome Technology—a mixture of active fibers that may help improve regularity.
  • Encourages the release of postbiotics to support the GI tract and help break down food.
  • Works to promote regular, healthy stool and reduce the risk of future episodes.
  • Formulated by Hill's trusted nutritionists and veterinarians.

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Nutritional Information

Feeding Instructions


Play Video: Learn More About Hill's Prescription Diet From Our Team of Experts
Learn More About Hill's Prescription Diet From Our Team of Experts

Frequently Bought Together

This Item – Hill's Prescription Diet Gastrointestinal Biome Chicken Flavor Dry Dog Food, 27.5-lb bag
Rated 4.7973 out of 5 stars
$127.99Chewy Price

Spend $100, Get a $15 eGift Card

Hill's Prescription Diet Gastrointestinal Biome Chicken & Vegetable Stew Wet Dog Food, 12.5-oz, case of 12
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$61.99Chewy Price

Spend $100, Get a $15 eGift Card

Purina Pro Plan Veterinary Diets FortiFlora Powder Digestive Supplement for Dogs, 30 count
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Total Price: $220.97

About Hill's Prescription Diet GI Biome Food for Dogs

Hill’s GI Biome Diet

Hill’s Prescription Diet Gastrointestinal Biome dog food takes a different approach to digestive care. Each formula uses a specific blend of active fibers, known as ActivBiome+, to help your dog’s stomach break down food more efficiently and promote healthier stools and regularity. It also contains Hill’s S+OX Shield ingredients, formulated to promote urinary health.

Activate the Gut Microbiome

When it comes to canine digestive health, the balance between good and bad bacteria is key. Promoting the growth of good bacteria helps keep problematic bacteria in check and supports ongoing digestive well-being.

Know the Signs of Digestive Issues

If you notice vomiting, diarrhea or soft stools, straining, stomach gurgling, flatulence, appetite changes, lethargy or depression in your dog, it may be from digestive trouble. See your vet for more insight and see if changing foods can help.

Risk Factors

Many things can trigger digestive issues in your pup, including food sensitivities, inflammation and bacterial, viral or parasite infections. Your vet can help determine what’s causing the trouble and figure out how diet can play a role.

Veterinarian Recommended

Vets know what’s best for their furry patients, so knowing that they place their trust in Hill’s can give you peace of mind.

About Hill's Pet Nutrition

For more than 70 years, Hill's Pet Nutrition has helped enrich and lengthen the special relationship between people and their pets by putting their passion for the health and happiness of animals into everything they do. They even partner with shelters to provide Hill's food to more than 9 million shelter pets.
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Top IngredientsChicken, Cracked Pearled Barley, Brewers Rice...New: Brewers Rice, Whole Grain Corn, Chicken Meal...Brewers Rice, Chicken Fat, Brown Rice...Whole Grain Wheat, Whole Grain Corn, Chicken Meal...Whole Grain Wheat, Powdered Cellulose, Chicken Meal...
Breed SizeExtra Small Breeds, Small Breeds, Medium Breeds...Extra Small Breeds, Small Breeds, Medium Breeds...Extra Small Breeds, Small Breeds, Medium Breeds...Extra Small Breeds, Small Breeds, Medium Breeds...Extra Small Breeds, Small Breeds, Medium Breeds...
Special DietSensitive Digestion, Veterinary Diet, With GrainSensitive Digestion, Veterinary Diet, With GrainVeterinary Diet, Pea-Free, With GrainVeterinary Diet, Weight Control, With GrainVeterinary Diet, Weight Control, With Grain
Food FlavorPoultry, ChickenPoultry, ChickenPoultry, ChickenPoultry, ChickenPoultry, Chicken
Health FeatureDigestive HealthDigestive HealthKidney CareWeight ManagementDiabetic Support, Digestive Health, Weight Management
Food FormDry FoodDry FoodDry FoodDry FoodDry Food

Questions & Answers

24 Customer Questions

Does this food cause extra thirst?
Answer by ChewyNov 23, 2020
The manufacturer does not currently have any records on side effects like extra thirst. We recommend consulting your veterinarian if you are unsure about possible side effects, as they have an entirely different industry insight, and they can give you a second opinion based on both professional experience and research.

Is this dog food made in the United States? Where are the ingredients sourced?
Answer by ChewyMar 15, 2021
Hills is manufactured in the United States. We source raw materials only from countries where there are reliable safety procedures in place, primarily in the United States, Japan, Canada, New Zealand, Australia and several European countries.

Asking for Great Dane breed - do you have information about the Calcium/ Phosphorus ratio? I didn't see it in the Guaranteed Analysis tab - thanks in advance
Answer by ChewyOct 16, 2019
This dry dog food formula has a calcium content of 1.18% and a phosphorus content of 0.68% on an dry matter basis.

How many cups are in a 16 lb bag of Hill's Biome dry dog food
Answer by ChewyJan 27, 2023
Each pound of this food is equivalent to 4.6 cups. The 8 pound bag contains approximately 36.8 cups. The 16 pound bag contains approximately 73.6 cups. The 27.5 pound bag contains approximately 126.5 cups.

ReviewsWrite a Review

Rated 4.7973 out of 5 stars
597 Ratings
Would recommend to a friend

590 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.
Rated 5 out of 5 stars
By Lacie on Sep 5, 2023

Worked like a charm!

I have a year old pembroke welsh corgi that had been suffering from on and off watery diarrhea over 3 months. Ruled out foreign objects, bacterial and parasitic causes with the vet, so the only thing left to try was diet. We switched her to this food and saw immediate improvement within 12 hours of the switch. No more diarrhea, no more expensive vet visits! Just really firm, healthy doodies. I never thought I’d be this excited about poop quality, but here we are!

Rated 5 out of 5 stars
By AF on Aug 26, 2023

Miracle Worker

I wish I had switched my dog to this months ago. We dealt with off and on diarrhea for 3 months. My vet initially suggested it but every time I'd think about going through the hassles of switching food, my dog would get better. Finally, in month three, after 10 days straight of bloody #2, trying two different vet-prescribed meds and a bland chicken and rice diet, I remembered this recommendation and made the switch. LITERALLY overnight the dog turned around. We went from bloody, water diarrhea to very soft #2 after just ONE meal. And within 24 hours, it was the firmest #2 of her life. I don't know what kind of scorcery is in this stuff but it was nothing short of magic.

Rated 5 out of 5 stars
By Carrie on Sep 7, 2023

This is the one

After adopting our dog she had serious tummy troubles for months due to all the antibiotics and treatments she was exposed to. We tried a few kinds of food and many many vet trips and finally this food is the one. She enjoys it, eats every bite, and we haven’t had tummy troubles for quite a while now so it seems to be working. Her stool is much darker and firmer but she is not straining and is regular. She has much more energy. So grateful for this food!

Rated 4 out of 5 stars
By amigadeperros on Aug 23, 2023

good but expensive

I would normally rate this 5 stars because it did solve the loose stool problem; however, I agree with some of the negative comments. It is expensive and I wonder why it is classified as a veterinary diet. It also definitely causes my dog to poop more, although not to the extent described in one review. It does also seem to make my dog more thirsty. She eats it all up, but I think she is a lab that would basically eat anything, since once I had to put some nasty-tasting medicine in her food and she ate it anyway. I would change to a Hills science diet but don't want to risk reaggravating the problem!

Rated 5 out of 5 stars
By DiggerDave on Aug 21, 2023

Worked for our Senior Lab/Shepherd

We have a senior Lab/Shepherd mix who always had a sensitive stomach, bad gas, and loose stools. We tried many foods, but none seemed to work. This food has just about eliminated all her problems, and she eats it very well, and she even stopped eating her droppings in the yard. I wish it wasn't so pricey, but I'm happy that she can lay in the room with us while we watch tv/movies without her clearing the room with her bad gas.

Rated 5 out of 5 stars
By crazicorgiladi on Aug 29, 2023

magic food

One of my dogs had been struggling with soft stool for months after having a plethora of GI issues this year. After ruling things out with the vet, they wanted us to try this food. Her poo is the most normal looking I have seen it in a long long time. This stuff is .:*magic*:.

Rated 5 out of 5 stars
By Tab on Aug 31, 2023

Picky eater loves

Our vet put our older dog on this food. He was having a lot of digestive issues. We were nervous if he would even eat it, since he was so picky. No need to worry he loves it and along with a regular probiotic his digestive issues have cleared right.

Rated 3 out of 5 stars
By Madi on Jul 18, 2023

Worsened Reverse Sneeze

My senior chihuahua mix loved Hill's prescription wet food, so I decided to give this dry kibble a try and attempt to make it his regular recipe. It has done wonders for his stomach sensitivities, but interestingly, worsened others. His stools have been much smaller and darker, and it seems to have exacerbated his reverse sneeze! I'm planning to switch to Solid Gold to see if he does better with that.

Rated 5 out of 5 stars
By Alexandra on Sep 22, 2023


Our dog was struggling to poop normally (straining, very loose or not at all) and our vet prescribed this. He is back to normal and willingly eats this food!

Rated 5 out of 5 stars
By Laurie on Jun 16, 2023

Amazing company!

I called last week to edit my autoship. I had shoulder surgery and asked for the 16 lb bag instead of the 27 lb one. No problem, it was done for me with your usual lovely service. Then I got a card in the mail with a Chewy mug and a hand written note wishing me a speedy recovery. Amazing!! This brought happy tears to my eyes; you are the most wonderful company to deal with!