Hill's Prescription Diet Gastrointestinal Biome Chicken Flavor Dry Dog Food, 27.5-lb bag

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About This Item

Details

  • This prescription formula is designed to support the bacteria in your dog's gut.
  • Utilizes Hill's ActivBiome Technology—a mixture of active fibers that may help improve regularity.
  • Encourages the release of postbiotics to support the GI tract and help break down food.
  • Works to promote regular, healthy stool and reduce the risk of future episodes.
  • Formulated by Hill's trusted nutritionists and veterinarians.

Ingredient Information

Feeding Instructions

FAQ

Learn More About Hill's Prescription Diet From Our Team of Experts

Digestive Care Nutrition

Hill’s offers a variety of digestive care foods that help promote a healthy gut microbiome, with easy-to-digest ingredients that are gentle on tummies.

Signs of Distress or Digestive Upset

A pet experiencing stress or digestive upset may exhibit an upset stomach, loose stool, constipation, flatulence and/or weight loss.

What Can Affect a Pet’s Digestion?

There are several factors that can play a role in digestive upset, including dietary indiscretion, infection, gut inflammation and stress.

Recommended by Veterinarians

Hill’s is a leader in cutting-edge food science and research, trusted and recommended widely by vets.

About Hill’s Pet Nutrition

In 1948, Hill’s changed the pet nutrition world by launching the first veterinarian-prepared food for a pet’s specific health needs. Seven decades and thousands of innovations later, they are still leading the charge in science-led nutrition.

Shop Hill's-Prescription-Diet

Questions & Answers

32 Customer Questions


My dog is on the gastrointestinal biome dog food for a year now. She had a in flamed colon. She still licks feet bad. Could her gut be inflamed and need a probiotic?

Answer by HelloOct 04, 2025
Rinse dogs paws off after walk, clean bedding in hot water and vacuum carpets/sweep floors weekly, use air purifier, to help control environmental allergies. I would avoid qpoquel...read the insert and google. The Apoquel product insert warns that the medication may cause existing cancers to worsen and mentions that new benign and malignant tumors have been observed in clinical studies.

My dog is small, are the kibbles small or large?

Answer by MaryNov 24, 2025
Small, about the size of a large pea.

Does this contain omega 3 fatty acids?


Does this food cause extra thirst?

Answer by ChewyNov 23, 2020
The manufacturer does not currently have any records on side effects like extra thirst. We recommend consulting your veterinarian if you are unsure about possible side effects, as they have an entirely different industry insight, and they can give you a second opinion based on both professional experience and research.

4.8
Rated 4.8 out of 5 stars
5767 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Digestibility

92% Positive

Ingredients

90% Positive

Nutritional Value

90% Positive

Palatability

86% Positive

2343 Customer Reviews



Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 4 out of 5 stars
By Tracie on Jan 22, 2026

Helped Calm My Dogs GI Distress!

Although expensive, this dog food helped my girl stop vomiting and diarrhea. I started her on the canned I'd formula 1st, before transitioning to the dry. I portion

Although expensive, this dog food helped my girl stop vomiting and diarrhea. I started her on the canned I'd formula 1st, before transitioning to the dry. I portion her meals 3x daily and it seems to help her digest it better. She likes the taste and actually gets excited when I'm getting it ready for her. I also add warm water to her kibble and allow it to absorb before feeding it to her. Thanks to chewy for contacting my vet for prescription and approval!! It helped me a lot:)


Rated 5 out of 5 stars
By Stephen on Jan 11, 2026

Magic

This stuff is almost like voodoo. My dog had a bad stomach for a week. Couldn’t solve. Somebody told me about this. Said every dog she gave it to responded quickly

This stuff is almost like voodoo. My dog had a bad stomach for a week. Couldn’t solve. Somebody told me about this. Said every dog she gave it to responded quickly. I asked a vet for it (they agreed it works). Dog was better after one meal. Yeah, it isn’t believable. But true. It’s so expensive I tried to get her off of it. Cut it 25% with good (what I considered expensive) food that my last sensitive-stomach shepherd did well on (got her to 14 good years). No good. Even cut just 25% wouldn’t work. Back on 100% for one meal and better. Can’t imagine how this is possible but there’s no doubt. Might need a second mortgage to afford it but looks like I’m with it for life (as vet says, you find something that works just stick with it).


Rated 3 out of 5 stars
By Cathy on Jan 23, 2026

Works but not healthy

It does work, but I don’t feel like it has a lot of vitamins, and nutrients in it. He has to eat more to keep his weight, and it makes him poop a lot more. They

It does work, but I don’t feel like it has a lot of vitamins, and nutrients in it. He has to eat more to keep his weight, and it makes him poop a lot more. They are normal stools, but I don’t think the dog food is a healthy choice. There was an old dog food contest where they said if the dogs ate less and poop less then that means the food has more vitamins, and nutrients in it. With that being the case, then this is lacking either vitamins, minerals, and/or nutrients.


Rated 5 out of 5 stars
By Dani on Jan 16, 2026

Great food but so expensive

My pup absolutely needs this food. There is no other food that he does this well on. But it is very frustrating that Chewy ALWAYS has deals on every other kind of

My pup absolutely needs this food. There is no other food that he does this well on. But it is very frustrating that Chewy ALWAYS has deals on every other kind of prescription except RX Dog Food. This product is wildly expensive. We get down to one or two bowls before we can scrape up enough to buy again. Please start adding coupons for RX Food. I am literally having to choose to feed him over me. Which I will always do, of course he comes before me. Please please add coupons for RX FOOD!!!


Rated 5 out of 5 stars
By Casandra on Jan 25, 2026

Tasty and prescription health benefits!

My 80lb yellow Lab has a sensitive tummy and had diarrhea all the time! When he was up for adoption, the vet at his center had just put him on Hills rx biome for

My 80lb yellow Lab has a sensitive tummy and had diarrhea all the time! When he was up for adoption, the vet at his center had just put him on Hills rx biome for digestion and it works! Better stools in less than a week! Yes , I know it's expensive , but I consider it an investment in his health! Fozzie approved!


Rated 5 out of 5 stars
By Charles on Jan 18, 2026

Expensive but worth it

We recently switched from one prescription diet to this. It caused a little extra gas at first, but now it works great. Our boy has sensitive stomach as many dogs

We recently switched from one prescription diet to this. It caused a little extra gas at first, but now it works great. Our boy has sensitive stomach as many dogs do and this has seemed to help solidify his stools. They aren’t totally solid, but a huge improvement. This does require a vet approval.


Rated 5 out of 5 stars
By Margo on Jan 20, 2026

Great service

We got this food for our dog Dixie she was having gland problems and we thought this food would help. We sadly had to put her down on 1/17/26 on her 14th birthday

We got this food for our dog Dixie she was having gland problems and we thought this food would help. We sadly had to put her down on 1/17/26 on her 14th birthday. She had diabetes, pancreatitis., UTI and she was not well. Thank you for your service.


Rated 4 out of 5 stars
By Jason on Jan 6, 2026

Vet prescribed - Velcro Seal on bag

I truly value the velcro straps attached to the bag, which help maintain its closure and freshness. Oro has not encountered any problems thus far with eating or

I truly value the velcro straps attached to the bag, which help maintain its closure and freshness. Oro has not encountered any problems thus far with eating or digesting the food. The most significant drawback is the price, which is outrageous. The company ought to feel embarrassed about their profit margins and excessive markup.


Rated 5 out of 5 stars
By Suzanne on Dec 28, 2025

Effective in resolving my dog’s issue

BELLA was experiencing blood in her poop in spite of eating a high-quality dried food. Her vet recommended that I change her diet Hills Gastrointestinal Biome dry

BELLA was experiencing blood in her poop in spite of eating a high-quality dried food. Her vet recommended that I change her diet Hills Gastrointestinal Biome dry food. Her vet told me that her own dog experienced the same bloody issue and that this food completely corrected it. That’s exactly what happened with us and I couldn’t be happier..


Rated 5 out of 5 stars
By Kimberly on Jan 10, 2026

Problem solved!

My Boston Terrier was having terrible issues with diarrhea and soft stool. After ruling out other medical issues, my vet suggested this. My dog consistently has

My Boston Terrier was having terrible issues with diarrhea and soft stool. After ruling out other medical issues, my vet suggested this. My dog consistently has formed stool now, provided that we are also careful about any treats she receives. Bonus is that she seems to like it.