Onguard Plus Flea & Tick Spot Treatment for Dogs, 45-88 lbs, 6 Doses (6-mos. supply)

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About This Item

Details

  • Contains the same two active ingredients as the leading national topical flea and tick brand.
  • Topical treatment kills all life stages of fleas and ticks on dogs at least eight weeks old and ranging from 45 to 88 pounds. Helps control infestations of chewing lice and sarcoptic mange mites.
  • Helps break the flea life cycle and rids your dog of flea eggs, larvae, pupae and adults. Also kills tick larvae, nymphs and adults.
  • Effective against fleas that cause flea allergy dermatitis as well as brown dog ticks, American dog ticks, lone star ticks and deer ticks that may carry Lyme disease, when used as directed.
  • Redesigned applicator makes it easier to apply this long-lasting and waterproof treatment that provides protection even after your dog has a bath, or gets wet from the rain or plays in water.

Ingredients

Instructions

FAQ

Learn More About Onguard Plus From Our Team of Experts

Questions & Answers

11 Customer Questions


who makes this product?

Answer by ChewyOct 07, 2020
Onguard Plus is exclusively made for and distributed by Chewy! We work closely with production partners to create and develop our own recipes and oversee production to ensure it adheres to our quality standards. Onguard Plus is manufactured in the United States.

Does this cover Lice as well?

Answer by ChewyMar 23, 2021
Onguard Plus Flea & Tick for Dogs kills all life stages of fleas and ticks on dogs at least 8 weeks old and ranging from 45 to 88 pounds. This topical also controls infestations of chewing lice and sarcoptic mange mites.

Does the flea have to bite the dog to kill the flea?

Answer by ChewyMay 23, 2021
This treatment kills fleas and ticks through contact with your pet's haircoat. They do not have to bite your dog for this to work.

Is this a preventative application or only if they already have fleas?

Answer by ChewyMay 14, 2021
This treatment will kill existing fleas and tick and remain effective for 30 days.

4.1
Rated 4.1 out of 5 stars
1040 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

82% Positive

Effectiveness

81% Positive

Ingredients

81% Positive

Long-Term Benefits

80% Positive

457 Customer Reviews



Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 5 out of 5 stars
By Jovani on Dec 1, 2025

Exactly like the name brand

I have two dogs. Each in a different weight class. One weighs less than 15 pounds and the other one weighs between 45 and 50 pounds. So buying flea medication isn’t

I have two dogs. Each in a different weight class. One weighs less than 15 pounds and the other one weighs between 45 and 50 pounds. So buying flea medication isn’t always the easiest and most affordable thing. After looking at the name brands, I looked at the active ingredients and found one that was closely similar. This is the second month and so far my dogs have shown no side effects and as far as I can see, there are no fleas. I would highly recommend someone to try it out as an affordable alternative to the namebrand flea topicals


Rated 5 out of 5 stars
By Theresa on Dec 22, 2025

From outdoor to indoor CATs

Looks & easy assembly. Now to get 2 outdoor cats to become indoor cats and for them to believe this tree to be a tree!! Hoping they will enjoy climbing on it and

Looks & easy assembly. Now to get 2 outdoor cats to become indoor cats and for them to believe this tree to be a tree!! Hoping they will enjoy climbing on it and scratching etc. Sprinkled it was catnip too. Almost 2 weeks later still no interest.


Rated 1 out of 5 stars
By Timothy on Nov 2, 2025

Does Not Kill Fleas

I tried this, thinking it was an awesome bargain; however all my pets (including cats that I purchased the appropriate product for), did not control fleas. I usually

I tried this, thinking it was an awesome bargain; however all my pets (including cats that I purchased the appropriate product for), did not control fleas. I usually buy Pet Armor Plus, and I have never seen fleas on my pets or in my home. With this Chewy product, all my pets have fleas crawling on them and my house has fleas in it! I am using natural remedies for my babies until I can safely apply the product that I normally use. I have been vacuuming and washing daily. It's been quite a hassle for me, and my babies are not too keen on the fleas either. Chewy has given me a refund on this product, but it doesn't help with all the extra work and frustration that I and my babies have been going through. This Onguard product does not help with fleas. It may help somewhat control ticks, because there has only been a few ticks on my pets that go outside. Definitely would not recommend this.


Rated 4 out of 5 stars
By John on Jan 5, 2026

Abby & I remain On Guard for the good results of ON GUARD PLUS !

Abby is blond lab and ticks that get on her wind up on her head. We are both thankful for ease of visibility and I have experienced that On Guard Plus works w

Abby is blond lab and ticks that get on her wind up on her head. We are both thankful for ease of visibility and I have experienced that On Guard Plus works well.


Rated 5 out of 5 stars
By Joy on Sep 14, 2025

Works BETTER THAN Frontline

I've been using this for years and especially in Florida we use this all year round and it works fantastic. And with automatic shipment I don't even have to remember

I've been using this for years and especially in Florida we use this all year round and it works fantastic. And with automatic shipment I don't even have to remember when the next order is due which is automatically shows up which makes it so convenient. This is great for my greyhounds no adverse effects.. and for the price you can't beat it I've had so many people tell me Frontline doesn't work for them and then I tell him to try this and this works great.


Rated 5 out of 5 stars
By Charlene on Nov 4, 2025

Works Great!!!

I was very pleased with the flea treatment and it did work well within 48 hours and on some of the animals 24 hours. It’s reasonably priced for people that can’t

I was very pleased with the flea treatment and it did work well within 48 hours and on some of the animals 24 hours. It’s reasonably priced for people that can’t afford to go to the vet and buy more expensive things..


Rated 2 out of 5 stars
By Nicole on Dec 26, 2025

I had to keep my dog separated for 24 hours

Product doesn’t seem to do the job. I still have fleas after applying it two weeks later not as many, but still there.

Product doesn’t seem to do the job. I still have fleas after applying it two weeks later not as many, but still there.


Rated 4 out of 5 stars
By Courtney on Nov 7, 2025

So far no complaints

I paired this with capstar and all of sudden the excessive itching stopped and the fleas started falling off. 4 stars for now until I know for sure that it did the

I paired this with capstar and all of sudden the excessive itching stopped and the fleas started falling off. 4 stars for now until I know for sure that it did the full job.


Rated 5 out of 5 stars
By donna on Nov 29, 2025

Works very well

This product worked very well on fleas and ticks. I would still get ticks on my dogs, but they would not attach.

This product worked very well on fleas and ticks. I would still get ticks on my dogs, but they would not attach.


Rated 3 out of 5 stars
By Dee on Sep 4, 2025

Kinda works

Don't know what to say, it kinda works. It has lessened the fleas but def hasn't got ride of em. Hoping before the end of the 6 month supply it will... IDK. I've

Don't know what to say, it kinda works. It has lessened the fleas but def hasn't got ride of em. Hoping before the end of the 6 month supply it will... IDK. I've always used Frontline and it works but, thought I'd try something new...