Cheristin Flea Spot Treatment for Cats, over 1.8 lbs

By Cheristin
Rated 4.2806 out of 5 stars


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$74.98Chewy Price
$71.23Autoship Price
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Total Price: $127.96

About This Item


  • Starts killing and preventing fleas within 30 minutes of application.
  • Kills 98 to 100% of fleas within 12 hours to put a quick stop to meowing and scratching.
  • Each treatment continues to work for one full month of nonstop protection.
  • Comes in an easy-to-use applicator that is non-greasy and gets down to the skin.
  • Gentle enough for cats and kittens 8 weeks of age and older.

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Play Video: Learn More About Cheristin From Our Team of Experts
Learn More About Cheristin From Our Team of Experts

Important Information

Fleas rise to the top of your pet's coat as they die, so consider it a triumph if you start seeing more fleas at first, after treating your pet. If you’re still seeing fleas after application, it may be because your pet has picked up new fleas from the environment, which may include other pets, surfaces and outdoor areas. It may take up to 30 days to break the entire flea life cycle. Additionally, you should also treat sources of new fleas (i.e., carpet, yard, etc.) to ensure complete flea control.

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Top IngredientsActive Ingredients: Spinetoram 11.2% Other Ingredients: 88.8%Dinotefuran, Fipronil and PyriproxyfenActive Ingredients: Imidacloprid 9.1%, Pyriproxyfen 0.46%.Active Ingredients : Fipronil 9.8% , (S)-methoprene 11.8%.Active Ingredients: Imidacloprid 9.1%, Pyriproxyfen 0.46%.
LifestageAdultKitten, Adult, SeniorAdultKitten, Adult, SeniorAdult
Small Pet TypeFerret

Questions & Answers

23 Customer Questions

It's been 3 weeks and my cat still has a bunch of fleas on his ears and nose. Should I apply another treatment and hope it will eventually work or assume it's not going to work for him and try something else?
Answer by ChewyAug 02, 2018
If you see fleas on your cat within a month after your pet receives flea treatment with Cheristin for cats, it is most likely these are new fleas that have very recently emerged from pupae and jumped onto the cat. These new fleas will be killed quickly before they can produce eggs that contaminate the environment.Consistent monthly application of Cheristin for cats should be maintained to provide continued protection for your cat against these fleas.

Is there shelf life on this product. If I don't use all of this product will I be able to use it next year
Answer by ChewySep 10, 2018
This product does not have an expiration date as long as the tubes remain sealed.

Is this the same strength that I can buy at the vet's office?
Answer by ChewyJun 27, 2018
This treatment is equivalent to treatments sold at a veterinarian office.

How do I know if the Cheristin flea medication is made in USA and bought from a reputable source?
Answer by ChewyDec 06, 2019
Cheristin for Cats is manufactured in Clinton, Indiana. Chewy sources all our products from manufacturer approved distributors or directly from the manufacturers. Chewy takes pride in ensuring that our furry friends’ well being is always our top priority. We have worked hard to partner with all of the manufactures to deliver 100% authentic products.

ReviewsWrite a Review

Rated 4.2806 out of 5 stars
1030 Ratings
Would recommend to a friend

1028 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.
Rated 5 out of 5 stars
By Jack on Sep 23, 2023

Works Great!

I recently purchased Cheristin for my cats and finally I have found drops that work! Advantage II wasn't working so I tried Nextstar and that didn't work either. Capstar always works but I needed something that would last all month and also repel fleas. I bought Cheristin and I'm happy with the results. It is a little messy and there is a lot in the tube. But that's fine if it works I'm ok with a little messy.. Also I'd like to just give some advice to people who may not know. Always read the directions. And please watch your cat after applying any kind of flea drops. If they act funny or start salivating excessively bath them in Dawn asap. If you give them a flea pill and they act funny or salivate excessively get them to the vet asap. I've had to do both of things for one of my cats. I always put the drops on earlier in the day so I can keep a close eye my cats.

Rated 5 out of 5 stars
By Chinookie on Sep 26, 2023

Starts working same day!

I’ve been using Cheristin for my 8lb cat for about a year now. It’s actually crazy how quick it starts to work. Twice in this last year ive forgotten and had to order flea meds going a week or so past my “give cat flea meds” sticker on the calendar. During both of those in-between times I started getting those itchy flea bites right on my ankle. Literally the day after giving my cat her meds no more bites. We live in an apartment where many of our neighbors also have cats but this medicine works wonders as long as we stay consistent.

Rated 5 out of 5 stars
By Cleo on Aug 28, 2023

Excellent pricing for a good flea treatment

I tried a different allergy topical treatment for my cat and found it did not work for even a week. Fleas are rampant outside now in our area (San Diego). They are in sand, they are in soil, and they are in grasses. It is an uphill battle. Ranger's fleas began dying immediately. He did not make licking the treatment off his sole purpose for living - which is a first - so I found that alone remarkable. He has started scratching again and it is still well within the 30-day period in which Cheristin is supposed to work. But fleas must bite in order to die. I see no mass invasion. I bought some natural product wipes for this interim which I use on his face and head to keep the bugs from his ears, chins, etc. So far, any fleas I have seen where he has lain were dying or dead. I received my order in 48 hours even though I ordered it on a weekend. Very impressed with Chewy!

Rated 1 out of 5 stars
By Freddie on Sep 7, 2023

Caused hair loss on application site

My cat had an adverse reaction to Cheristin which caused a large patch of his fur on the application site to fall out, leaving a substantial bald patch. Chewy customer service was great and refunded my purchase immediately and encouraged me to report the adverse reaction to the manufacturer. I would recommend to pet owners that they use another flea control product if their cat has allergies or sensitive skin.

Rated 5 out of 5 stars
By linda on Sep 20, 2023


This flea treatment was a life saver. The day after I put this on my cats I had dead fleas everywhere. After two weeks I am not finding any fleas in my home or on my cats. Highly recommend Cheristin. Thank you for a great product that really works. Worth the price.

Rated 5 out of 5 stars
By Heather on Sep 11, 2023

Cheristin Flea treatment

I was skeptical that this would work. I had tried everything on my cats. After 1 application, my cats are flea free. It really did work in 30 minutes. It has been 2 weeks since I put the product on the cats, and they remain flea free. Will recommend and will purchase again!

Rated 5 out of 5 stars
By Lee on Aug 11, 2023

Best Flea Treatment I have ever Seen!

I have spent a monumental amount of money on different flea treatments over the counter and at the veterinarian's office and this product I applies one time to all my babies and it killed every flea and all the eggs and my cats are the happiest they have been in a long time. I won't use anything else again. I would recommend this to anyone who has Flea problems, we were over run with them and nothing else worked.

Rated 5 out of 5 stars
By Pamela on Sep 26, 2023

The best!!!

This is the only topical medication that has ever worked on my babies! We’ve tried everything else and would continue to find fleas. Our babies are finally flea free! I couldn’t recommend this stuff enough!

Rated 5 out of 5 stars
By Boots on Sep 28, 2023

Tease n flicks

Actually I mean fleas & ticks. I have 3 cats so there was only 1 treatment in the box. It seems to be working ok. The cats ate still scratching but not as much. I will be buying at least one more box.

Rated 4 out of 5 stars
By Catlover12 on Jul 20, 2023

Vet said this is the only OTC that works; gross on fur

As the title says. It seems to work since we haven't had a flea issue (knock on wood). We switch between this and revolution since the latter is too expensive for us to afford monthly. This goes on really stinky and makes the cat fur gross, kind of like what I think would happen if you put hair gel on the cat's fur. It hurts my throat from being around it - i dont know if it's the stinky smell or harsh chemicals, so I'm sure it's more unpleasant for cats. I suspect it causes lethargy in one of my cats the next day after applying. But I'm glad to have a cheaper alternative and no serious health issues.