ONGUARD PLUS Flea & Tick Spot Treatment for Cats, over 1.5 lbs, 6 Doses (6-mos. supply) -

Onguard Plus Flea & Tick Spot Treatment for Cats, over 1.5 lbs

By Onguard Plus
Rated 2.9452 out of 5 stars

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$31.34Chewy Price
$29.77Autoship Price
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About This Item


  • Contains the same two active ingredients as the leading national topical flea and tick brand.
  • Topical treatment kills all life stages of fleas and ticks on cats at least eight weeks old and 1.5 to 22 pounds. Also helps control infestations of chewing lice.
  • Helps break the flea life cycle and rids your cat of flea eggs, larvae, pupae and adults. Also kills tick larvae, nymphs and adults.
  • Effective against fleas that cause flea allergy dermatitis as well as brown dog ticks, American dog ticks, lone star ticks and deer ticks that may carry Lyme disease, when used as directed.
  • Redesigned applicator makes it easier to apply this long-lasting and waterproof treatment that provides protection even after your cat has a bath or gets their fur wet.

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Play Video: Learn More About Onguard Plus From Our Team of Experts
Learn More About Onguard Plus From Our Team of Experts

Questions & Answers

13 Customer Questions

does on guard have expiration date
Answer by ChewyApr 17, 2022
This treatment has no expiration date.

Does the kitten have to be both 8 weeks and over 1.5lbs?. Or one or the other? I found kittens I took them in they have fleas they’re about 7 weeks now old healthy and @1.5 to 2lbs
Answer by ChewyOct 08, 2020
Kittens must be both 8 weeks old and weigh over 1.5-pounds to use this treatment.

Can you apply an ear mite solution at the same time that you administer this tick & flea spot treatment? Or should I do them on 2 separate days?
Answer by ChewyApr 14, 2021
Please consult with your veterinarian before giving your pet multiple treatments/preventatives.

is this product quick drying
Answer by ChewyMar 31, 2021
The topical will be dispersed over your cat’s body through their natural oils and attached to the hair follicles. This process can take up to 24 hours. Do not apply more often than once every 4 weeks.

ReviewsWrite a Review

Rated 2.9452 out of 5 stars
292 Reviews
Would recommend to a friend

292 Customer Reviews

Filter by reviews that mention

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.
Rated 1 out of 5 stars
By Avery on Feb 21, 2023

Caused irritation and hair loss

Three days after applying Onguard, I noticed hair loss and irritated skin on one of my cats at the application site. I've never had an issue using other topical flea meds, like Revolution. I will absolutely not be purchasing this product again.

Rated 1 out of 5 stars
By Flipper on Feb 28, 2023

On guard was off

I bought 4 of the 6 ok of Onguard for cats cause I have 21 fur babies. Well unfortunately this product DID NOT hold up to what it says. All my cats still have fleas so I will be spending more money on a better product. Beware ~ product did not work ~ at all !!!

Rated 5 out of 5 stars
By Mike on Jan 13, 2023

Best immediate meds

I bought this because my topical and flea collar still not working as well. I gave each of my 4 one of these pills and within 10 to 15 mins I could tell it was cats were picking and scratching...then within an hour done.....I have not seen a flea and no picking or thing I've used by far. Thank you chewy!!!!

Rated 5 out of 5 stars
By Susan on Feb 3, 2023

Cat Products

Lots of choices. Always kept in the loop of deliveries. Good products. Having things delivered is so much easier than buying heavy items and getting it home. Especially for an older person (me).

Rated 1 out of 5 stars
By Sara on Jan 13, 2023

Just does nothing

I put this on my cats (and the dog formula on my dog) for two months and it was a waste of money and time. Unfortunate, because I trusted Chewy. Going to have to spend more for something that works.

Rated 2 out of 5 stars
By Cathy on Dec 18, 2022

Doesnt seem to work very well

You asked so I will tell you. I am trying to find a topical flea medicine that is reasonably priced that will work. I have tried Frontline Plus & it didnt work, so gave this a try, it isnt working either! I have 4 cats that I put topical flea medicine on & I need to find something that works besides Revolution ( which is the best but too expensive & need a prescription for.) Any other ones I should try? Thanks.

Rated 1 out of 5 stars
By disappointed on Nov 9, 2022

didn’t work

I used this on my pets for quite a few months and still fought with fleas. I just switched back to Frontline plus and within 24 hours my pets are soooo much less itchy. I feel guilty that they suffered with fleas for so long when I could have just spent the extra money for something that worked. Was hoping this would work considering that it’s more affordable. But you get what you pay for I suppose

Rated 5 out of 5 stars
By 2022 on Nov 20, 2022

It helped control our awful infestation!

We bought this stuff back in January and our cats have been on it ever since. It broke the flea cycle but you HAVE to take care of every part of your house. This stuff does it’s job on the cats but flea eggs still live in carpets and couches etc. I highly recommend this.

Rated 1 out of 5 stars
By Karen on Nov 9, 2022

Onguard Plus

We have 3 cats, 2 longhair, one shorthair. The short-hair is the only one that had a reaction. He lost a circle of hair at the treatment site on the back of his neck. Neither of the other two had any reaction to it at all. Tossed the rest of the applications.

Rated 5 out of 5 stars
By Nemo on Feb 5, 2023

Onguard drops

As far as I can tell it's working I've only put it on him about 10 days ago. I see no flee eggs