Advantage II Flea Spot Treatment for Cats, 5-9 lbs, 6 Doses (6-mos. supply)

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About This Item

Details

  • Flea protection for small cats weighing 5 to 9 pounds, at least 8 weeks of age.
  • Easy-to-apply monthly topical treatment.
  • Delivers total flea protection and kills adult fleas, flea larvae and flea eggs through contact.
  • Starts killing fleas the same day and keeps working for 30 days.
  • Fragrance-free formula is waterproof after 24 hours of application.

Ingredients

Instructions

Size

FAQ

Learn More About Advantage II From Our Team of Experts

Important Information

Fleas rise to the top of your pet's coat as they die, so consider it a triumph if you start seeing more fleas at first, after treating your pet. If you’re still seeing fleas after application, it may be because your pet has picked up new fleas from the environment, which may include other pets, surfaces and outdoor areas. It may take up to 30 days to break the entire flea life cycle. Additionally, you should also treat sources of new fleas (i.e., carpet, yard, etc.) to ensure complete flea control.

About Advantage II for Cats

Get the Advantage Over Fleas

Advantage II topical flea treatment and prevention for cats kills fleas on your cat within 12 hours, and it continues to protect for 30 days. It’s easier to use than hard-to-swallow pills—simply apply the convenient flea drops directly to your cat's skin once a month. Best of all, Advantage II is available without a prescription.

Flea Treatment and Prevention

Advantage II doesn't just treat fleas––it breaks the flea lifecycle to prevent reinfestation.

Works Through Contact

These flea drops kill adult fleas, flea larvae, and flea eggs through contact, so they don't have to bite your cat to die.

Same-Day Effectiveness

Advantage II starts killing fleas on cats within 12 hours, and it continues to prevent reinfestations for four weeks.

No Prescription Needed

You don’t have to go to the vet to get quality flea protection for your cat—simply buy and apply.

Fragrance-Free

This flea topical formula is fragrance-free and waterproof 24 hours after application.

Frequently Asked Questions

Can I Use Advantage II on My Cat?

Advantage II is for cats and kittens 8 weeks of age and older. It comes in three sizes: Kitten (2-5 lbs.), Small Cat (5-9 lbs.), and Large Cat (9+ lbs.). Choose the right size based on your pet's weight. Advantage II for cats is suitable for both indoor and outdoor cats, but not for use on dogs.

How Do I Apply Advantage II?

Once you break the seal on the tube, part the hair at the base of your cat’s skull until the skin is visible. Squeeze the tube to expel the entire contents directly onto the skin in that one spot. Do not get this product in your cat’s eyes or allow your cat to ingest it.

The Advantage Family

Get the Advantage over fleas with complete flea protection for your pet, home, and yard. The Advantage family of products has everything you need for a complete flea treatment and prevention plan, including monthly topical treatments, pet shampoos and sprays, household sprays for carpets and crevices, and even a yard and premise spray. Just be sure to get the right product for each need and use only as directed.

Shop K9 Advantix II

Questions & Answers

29 Customer Questions


how many cc are in one application tube?

Answer by ChewyAug 04, 2018
Each application tube contains 0.4 cc.

Does Advantage 2 protect against mosquitoes also?

Answer by ChewyJun 16, 2018
This product has not been tested to repel mosquitoes.

Does this product kill worms?

Answer by ChewyJan 25, 2021
This treatment does not kill worms, it is formulated to kill fleas and ticks.

is thus effective on chewing lice

Answer by ChewyDec 28, 2019
This flea treatment does not treat lice.

4.5
Rated 4.5 out of 5 stars
4656 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

82% Positive

Effectiveness

82% Positive

Ingredients

79% Positive

Long-Term Benefits

83% Positive

2001 Customer Reviews



Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 3 out of 5 stars
By Lyn on Jan 14, 2026

Very small 18"

This is a very nice burrow for cats but it is very small and my cats are large. I followed suggestions in other reviews and cut the closed end out. My cats play

This is a very nice burrow for cats but it is very small and my cats are large. I followed suggestions in other reviews and cut the closed end out. My cats play with it and one cat grab the toy and ran to the house with the tunnel and toy. It was cracka because the other cat was chasing her. It's probably more designed for kittens. I have a large 7 lb cat very long and she hasn't gone in inside of it except for one. 10 lb already and she's a little bit leery about going inside also because it's so small. By cutting the closed and off they had more interest in it. If you have large cats I suggest not to buy this toy.


Rated 3 out of 5 stars
By Emily on Dec 28, 2025

Cat had a reaction

My cat was using this flea medicine for many months. Most recent application caused my cat to rip out all of his fur where the medication was applied. It cost us

My cat was using this flea medicine for many months. Most recent application caused my cat to rip out all of his fur where the medication was applied. It cost us many vet visits to treat the reaction spot, and although he is better now, I have been too scared to apply flea medication again.


Rated 5 out of 5 stars
By Janet on Dec 15, 2025

Works with no side effects!

I have tried other brands with a similar application, some work a little, some make my cats sick for a day or two. After having tried flea shampoos, washing, spraying

I have tried other brands with a similar application, some work a little, some make my cats sick for a day or two. After having tried flea shampoos, washing, spraying bedding, carpets, and furniture with insecticide, powdering cats and bedding with diatomaceous earth, I finally tried Advantage. Clearly the best for my particular cats. Fleas are gone and the cats are happy again.


Rated 5 out of 5 stars
By Julie on Dec 29, 2025

Works great!

This stuff actually works. I originally bought it at my vets office, but found it here for less. It also did NOT kill any of my babies like Only Naturals did. I've

This stuff actually works. I originally bought it at my vets office, but found it here for less. It also did NOT kill any of my babies like Only Naturals did. I've had to use it twice as the first time I tasted my house did not work. Hopefully this time it killed all those pesky fleas.


Rated 5 out of 5 stars
By Raven on Nov 28, 2025

It didn't kill my cat but killed the fleas

I was terrified it would cause seizures in my old, frail, compromised girl who has CH and is prone to seizures but I had no choice the fleas were eating her alive

I was terrified it would cause seizures in my old, frail, compromised girl who has CH and is prone to seizures but I had no choice the fleas were eating her alive. So with much prayer I used it on Gina and the same for larger cats on the other two. It worked better than any other brands I have used in the past and no sude effects! I am very happy with the safety and performance of this product.


Rated 5 out of 5 stars
By Jessica on Dec 18, 2025

Worked and worked fast.

We recently took in a stray kitten. She had no signs of fleas at first but within a few days we found flea dirt. Immediately ordered this. It was here within 48

We recently took in a stray kitten. She had no signs of fleas at first but within a few days we found flea dirt. Immediately ordered this. It was here within 48 hours. In that time we were flea combing daily and found 2 fleas the next day. We didn't find a single one on any of our four cats after administering this.


Rated 1 out of 5 stars
By Tina on Jan 5, 2026

Don't waste your money! This brand doesn't work!!

I've purchased this multiple times to give it time to work and is hasn't worked for my cats!! It's so expensive and I'm very disappointed on all the money that has

I've purchased this multiple times to give it time to work and is hasn't worked for my cats!! It's so expensive and I'm very disappointed on all the money that has been wasted. I've just ordered another brand hopefully that does the trick.


Rated 5 out of 5 stars
By Holly on Nov 24, 2025

Great product

Works fast to get rid of fleas on my cats, no residue on them afterwards and no smell. I think the fleas have gotten immune to the frontline I had been using for

Works fast to get rid of fleas on my cats, no residue on them afterwards and no smell. I think the fleas have gotten immune to the frontline I had been using for years, it never got rid of them completely just reduced their numbers. The day after I applied advantage I ran the flea comb through and got not a single flea.


Rated 5 out of 5 stars
By Joyce on Nov 18, 2025

it works !

I had a flea infestation from some foster cats that I thought had been on flea preventative. Tried several brands but nothing was helping. A vet nurse advised me

I had a flea infestation from some foster cats that I thought had been on flea preventative. Tried several brands but nothing was helping. A vet nurse advised me to try this - she said it was the best thing she had tried. I was able to get it on every cat , including my little old feral cat that stays outside . It does not have a chemical odor so they aren't ducking away and running from it.


Rated 5 out of 5 stars
By Ann on Dec 31, 2025

Works well for my outdoor cat

This product works well for my outdoor cat. She's a community rescue and doesn't like being handled much. I can get this on her while she enjoys a treat and she

This product works well for my outdoor cat. She's a community rescue and doesn't like being handled much. I can get this on her while she enjoys a treat and she has flea treatment coverage for a month.