Advantage II Flea Spot Treatment for Cats, over 9 lbs, 1 Dose (1-mo. supply)

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About This Item

Details

  • Flea protection for cats weighing over 9 pounds, at least 8 weeks of age.
  • Easy-to-apply monthly topical treatment.
  • Delivers total flea protection and kills adult fleas, flea larvae and flea eggs through contact.
  • Starts killing fleas the same day and keeps working for 30 days.
  • Fragrance-free formula is waterproof after 24 hours of application.

Ingredients

Instructions

Size

FAQ

Learn More About Advantage II From Our Team of Experts
Important Information

Fleas rise to the top of your pet's coat as they die, so consider it a triumph if you start seeing more fleas at first, after treating your pet. If you’re still seeing fleas after application, it may be because your pet has picked up new fleas from the environment, which may include other pets, surfaces and outdoor areas. It may take up to 30 days to break the entire flea life cycle. Additionally, you should also treat sources of new fleas (i.e., carpet, yard, etc.) to ensure complete flea control.

About Advantage II for Cats

Get the Advantage Over Fleas

Advantage II topical flea treatment and prevention for cats kills fleas on your cat within 12 hours, and it continues to protect for 30 days. It’s easier to use than hard-to-swallow pills—simply apply the convenient flea drops directly to your cat's skin once a month. Best of all, Advantage II is available without a prescription.

Flea Treatment and Prevention

Advantage II doesn't just treat fleas––it breaks the flea lifecycle to prevent reinfestation.

Works Through Contact

These flea drops kill adult fleas, flea larvae, and flea eggs through contact, so they don't have to bite your cat to die.

Same-Day Effectiveness

Advantage II starts killing fleas on cats within 12 hours, and it continues to prevent reinfestations for four weeks.

No Prescription Needed

You don’t have to go to the vet to get quality flea protection for your cat—simply buy and apply.

Fragrance-Free

This flea topical formula is fragrance-free and waterproof 24 hours after application.

Frequently Asked Questions

Can I Use Advantage II on My Cat?

Advantage II is for cats and kittens 8 weeks of age and older. It comes in three sizes: Kitten (2-5 lbs.), Small Cat (5-9 lbs.), and Large Cat (9+ lbs.). Choose the right size based on your pet's weight. Advantage II for cats is suitable for both indoor and outdoor cats, but not for use on dogs.

How Do I Apply Advantage II?

Once you break the seal on the tube, part the hair at the base of your cat’s skull until the skin is visible. Squeeze the tube to expel the entire contents directly onto the skin in that one spot. Do not get this product in your cat’s eyes or allow your cat to ingest it.

The Advantage Family

Get the Advantage over fleas with complete flea protection for your pet, home, and yard. The Advantage family of products has everything you need for a complete flea treatment and prevention plan, including monthly topical treatments, pet shampoos and sprays, household sprays for carpets and crevices, and even a yard and premise spray. Just be sure to get the right product for each need and use only as directed.

Shop K9 Advantix II

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Questions & Answers

45 Customer Questions

I have more than 1 cat, what if one of the other cats tries to lick it off the other cat? Should they be monitored after application?

Since the product is applied to your cats neck, what about the fleas on the cats belly will they move to the neck?

Answer by Chewy • Sep 19, 2017
The active ingredients of Advantage II work to attack the fleas, no matter where they're located on your cat.

can you use before 30 days is up

Answer by Chewy • May 15, 2021
Under normal conditions this product is effective for one month. However, in cases of severe flea infestation, retreatment may be necessary earlier than 4 weeks. Do not retreat more often than once every 14 days for kittens or once every 7 days for small and large cats. After flea control is attained, return to a monthly retreatment schedule.

If my cat weighs about 9 lbs on the dot, which treatment should I use?

Answer by Chewy • May 24, 2019
If your cat weighs 9 pounds, it's recommended to use the Advantage II Flea Treatment for Small Cats 5 to 9 pounds. Use this treatment if they're over 9 pounds.
Reviews
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4.5
Rated 4.5 out of 5 stars
10337 Ratings
Terms & Conditions

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

83% Positive

Effectiveness

82% Positive

Ingredients

80% Positive

Long-Term Benefits

82% Positive

4459 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.

Rated 5 out of 5 stars
By Carol on Jan 17, 2026

Great price and works the same as the more expensive ones!

It was very easy to determine and pick the correct flea medication that I needed; having a picture of a cat on the front of the box made it so easy to know that

It was very easy to determine and pick the correct flea medication that I needed; having a picture of a cat on the front of the box made it so easy to know that this is for the correct type of animals and then it was also very easy to see what pounds this is used for. None of my cats had any allergic skin reactions to this product. The smell of this product was not as harsh as some other flea medications that I have purchased in the past.

Rated 5 out of 5 stars
By Carol on Dec 30, 2025

A necessary evil

I hate the fact I have to put chemicals on my cat. But in the south, you have too. I tried "natural" methods and they don't work. I do not let my cat roam outside,

I hate the fact I have to put chemicals on my cat. But in the south, you have too. I tried "natural" methods and they don't work. I do not let my cat roam outside, but he does enjoy the screened porch. Also, I'm sure I introduce sand fleas in the house just working in my yard. When I was on my "natural" kick, he had scabs various places on his body from fleas. DE dried his skin horrible. Regular baths dried him out and he even got a respiratory infection in the AC from being wet. Advantage is the only way to go. Keeps him flea/scab free. Keeps me scratch free from the baths.

Rated 5 out of 5 stars
By Kayla on Jan 9, 2026

Worked for active fleas

My cat somehow got a gnarly flea infestation. After two months of this, vacuuming everyday, and doing the flea comb everyday, the fleas are gone! I really think

My cat somehow got a gnarly flea infestation. After two months of this, vacuuming everyday, and doing the flea comb everyday, the fleas are gone! I really think it’s helping to prevent more from living on him if they are still in the house. This is a new staple in our household. Also, he is an old cat (13 years, 15lbs) and had no adverse side effects or reactions.

Rated 5 out of 5 stars
By Zephyr on Dec 10, 2025

Worked immediately and amazingly

Within just 4-5 days of applying the flea med he was nearly clear of adult fleas. And tonight, to the dismay of my worm phobia, i found that pretty much an entire

Within just 4-5 days of applying the flea med he was nearly clear of adult fleas. And tonight, to the dismay of my worm phobia, i found that pretty much an entire generation of flea larvae had jumped ship onto his favorite pillow. I will have to clean up and make sure these disgusting creatures die by treating my carpets and washing a looot of bedding but the fact so many of them left the cat is definitely a sign of an effective treatment and an itchless kitty. I did end up throwing away that pillow in abject horror and disgust, but i blame the fleas rather than the product itself.

Rated 5 out of 5 stars
By Robert on Dec 2, 2025

Works well, better than other brands for my cat in Los Angeles

I saw a drastic difference when I started my cat Fang on this vs Frontline- maybe the fleas in Los Angeles have grown more accustomed to Frontline? Not sure, but

I saw a drastic difference when I started my cat Fang on this vs Frontline- maybe the fleas in Los Angeles have grown more accustomed to Frontline? Not sure, but previously my indoor/outdoor cat Fang would still have some fleas despite being on Frontline. Then I switched to Anvantage and literally that same evening I found 10-15 dead fleas on his bedding. It worked fast and it seems to be more effective; he has substantially less fleas in the past 6 months that he's been on Advantage.

Rated 2 out of 5 stars
By Robert on Dec 7, 2025

Allergic reaction

Although i believe it took care of the fleas as I’m not seeing them on my cats, but both of my cats are having reactions to this product. They have bumps on their

Although i believe it took care of the fleas as I’m not seeing them on my cats, but both of my cats are having reactions to this product. They have bumps on their skin and they’re itching and biting themselves more, one of my cats now has a huge bald spot on his back where he has literally pulled out his own hair trying to get relief from the skin irritation. I will not be using this product again.

Rated 5 out of 5 stars
By Tonya on Jan 5, 2026

We haven't had a flea out-break.

While using other brands, we had flea outbreaks. We haven't had an outbreak since we started using this brand. It doesn't burn their skin, nor does it make them

While using other brands, we had flea outbreaks. We haven't had an outbreak since we started using this brand. It doesn't burn their skin, nor does it make them lose their hair. It is wet for a day, and you can't touch the treated area until it is dry.

Rated 1 out of 5 stars
By Tammy on Dec 19, 2025

Bad reaction

I have this product to my 12lb, 10 month old long haired Maine Coon mix kitten. Within 24-30 hours after putting g it on her, she had bad diarrhea and vomit

I have this product to my 12lb, 10 month old long haired Maine Coon mix kitten. Within 24-30 hours after putting g it on her, she had bad diarrhea and vomit. What a mess with a long haired cat. I called the manufacturer to report the issue. They gave me a case number in case she has any more issues.

Rated 1 out of 5 stars
By Tina on Jan 5, 2026

Doesn't work!

I've purchased this multiple times to give it time to work and is hasn't worked for my cats!! It's so expensive and I'm very disappointed on all the money that has

I've purchased this multiple times to give it time to work and is hasn't worked for my cats!! It's so expensive and I'm very disappointed on all the money that has been wasted. I've just ordered another brand hopefully that does the trick.

Rated 5 out of 5 stars
By Jean on Dec 8, 2025

Worked within 2 days

I switched to use this treatment after using Frontline to try something new. I have a feeling the Frontline treatment is ending sooner than a month. This product

I switched to use this treatment after using Frontline to try something new. I have a feeling the Frontline treatment is ending sooner than a month. This product is doing very well for our outdoor/indoor cat! She didn't have any visibly side effects and the flea eggs have stopped appearing. Great product! We will continue to use it.