ADVANTAGE II Flea Spot Treatment for Cats, over 9 lbs, 1 Dose (1-mo. supply) -

Advantage II Flea Spot Treatment for Cats, over 9 lbs

By Advantage II
Rated 4.2447 out of 5 stars
Pet Weight

$15.98Chewy Price
$16.98Chewy Price
$15.18Autoship Price
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About This Item


  • Veterinarian-recommended treatment kills all life stages of fleas on kittens and cats 8 weeks or older and weighing over 9 pounds.
  • Begins working within 12 hours to kill fleas on contact.
  • Kills eggs, larvae and adult fleas to break the life-cycle and help prevent re-infestation.
  • Waterproof formula continues working for up to four weeks, even after bathing.
  • Convenient, monthly topical application contains imidacloprid and pyriproxyfen; available in packs of 2, 4 or 6 treatments.

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Play Video: Learn More About Advantage II From Our Team of Experts
Learn More About Advantage II From Our Team of Experts

Important Information

Fleas rise to the top of your pet's coat as they die, so consider it a triumph if you start seeing more fleas at first, after treating your pet. If you’re still seeing fleas after application, it may be because your pet has picked up new fleas from the environment, which may include other pets, surfaces and outdoor areas. It may take up to 30 days to break the entire flea life cycle. Additionally, you should also treat sources of new fleas (i.e., carpet, yard, etc.) to ensure complete flea control.

Questions & Answers

31 Customer Questions

my cat weighs 19#. is one dose enough?

Since the product is applied to your cats neck, what about the fleas on the cats belly will they move to the neck?
Answer by ChewySep 19, 2017
The active ingredients of Advantage II work to attack the fleas, no matter where they're located on your cat.

can you use before 30 days is up
Answer by ChewyMay 15, 2021
Under normal conditions this product is effective for one month. However, in cases of severe flea infestation, retreatment may be necessary earlier than 4 weeks. Do not retreat more often than once every 14 days for kittens or once every 7 days for small and large cats. After flea control is attained, return to a monthly retreatment schedule.

Do indoor cats need this?
Answer by ChewyMar 07, 2019
It is generally recommended to treat indoor pets. Fleas may be introduced into the home by coming in on another pet or even onto a person. If you are uncertain, we recommend consulting with your veterinarian who is familiar with flea information for your specific location.

ReviewsWrite a Review

Rated 4.2447 out of 5 stars
2497 Reviews
Would recommend to a friend

2497 Customer Reviews

Filter by reviews that mention

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.
Rated 1 out of 5 stars
By Cindy on Feb 25, 2023

Take Heed - Caution!

My cat had an adverse reaction to this product. Perhaps it was a bad lot as I have used this product in the past. This time my cat was hyper grooming and scratching to the extent of massive fur loss as if this was a human interferon product - all over his body. And, the fleas remain!!! I researched and found online negative experiences: Cats have died, gone blind, etc... from this product. I immediately implemented colloidal silver into his water to assist his immune system. Scary. I can only hope he will recover fully. This is worthy of a negative rating.

Rated 5 out of 5 stars
By keyccrazy on Mar 27, 2023

Great Product

I was really in need of something to kill fleas off my 3 yr old house kitty who hangs out on my screened porch in FL a lot. Advantage did the trick in one day, it was such a relief seeing her not constantly going after fleas!

Rated 5 out of 5 stars
By Jenna on Mar 16, 2023

Exactly what I needed

Chewy is the most reliable company, I have been ordering for 8 years and every single order has been perfect, affordable, and in a timely manner. This is my favorite company on gods green earth, I wish I could work for them!

Rated 4 out of 5 stars
By Betty on Mar 19, 2023

Care during shipping

The Advantage II product is fine. I have a MAJOR problem with the packing used during shipment. When I received, the package was completely demolished. The packs of Advantage was all in the carton itself.

Rated 5 out of 5 stars
By woollydeb on Mar 23, 2023

good flea control

I have used Advantage for a long time. It works well on my indoor only cat. Easy to apply and only once a month. I put it on him in the morning and it has dried by the next morning.

Rated 1 out of 5 stars
By KatieG on Jan 28, 2023

No Longer Works

I have been rotating flea treatments for my 3 cats since none seem to work anymore, it seems fleas have become resistant. I noticed a small improvement for 2-3 days after applying Advantage, then all 3 cats were scratching again like crazy. I am at my wits end and don't know if anything works anymore. I just ordered a different brand, hoping it works better than Advantage. All of them are pretty expensive, I wouldn't mind if one of them only worked. Sigh...

Rated 5 out of 5 stars
By David on Mar 12, 2023


I have been using Advantage I I for many years. It works better than any other flea medicine I have ever tried. I will continue to use it. Rainbow,my cat remains flea free as long as I use it.

Rated 1 out of 5 stars
By catmom1 on Jan 20, 2023

not effective

i’ve tried using this product on/off for months now. every time i think it’s working and the fleas are finally gone, there’s always re-infestation. i’ve tried baths, treatment, nonstop cleaning, and thought i was finally seeing progress. these stopped working on our cats, so it’s time to keep looking for a solution that’ll actually work to keep the fleas gone and my cat babies comfortable.

Rated 1 out of 5 stars
By Babe on Jan 10, 2023

Does Not Work

This is the first time since 2006 that my dog and cat got fleas. One month ago applied this product. 2 weeks later she still has fleas. So I put another application on her. Still has them. We are going to the doggy doctor tomorrow to get a prescription cat flea medicine. I am out $50.00 on this product plus the $50.00 office visit tomorrow.

Rated 1 out of 5 stars
By Peggy on Mar 22, 2023

Extremely difficult to open vial

I'm a senior, this vial is so tiny I can't open it. Kept reading the instructions, dumb won't be purchasing this again