ADVANTAGE II Flea Spot Treatment for Cats, over 9 lbs, 12 Doses (12-mos. supply) -

Advantage II Flea Spot Treatment for Cats, over 9 lbs

By Advantage II
Rated 4.2509 out of 5 stars
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$99.96Chewy Price
$94.96Autoship Price
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About This Item


  • Veterinarian-recommended treatment kills all life stages of fleas on kittens and cats 8 weeks or older and weighing over 9 pounds.
  • Begins working within 12 hours to kill fleas on contact.
  • Kills eggs, larvae and adult fleas to break the life-cycle and help prevent re-infestation.
  • Waterproof formula continues working for up to four weeks, even after bathing.
  • Convenient, monthly topical application contains imidacloprid and pyriproxyfen; available in packs of 2, 4 or 6 treatments.

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Play Video: Learn More About Advantage II From Our Team of Experts
Learn More About Advantage II From Our Team of Experts

Important Information

Fleas rise to the top of your pet's coat as they die, so consider it a triumph if you start seeing more fleas at first, after treating your pet. If you’re still seeing fleas after application, it may be because your pet has picked up new fleas from the environment, which may include other pets, surfaces and outdoor areas. It may take up to 30 days to break the entire flea life cycle. Additionally, you should also treat sources of new fleas (i.e., carpet, yard, etc.) to ensure complete flea control.

About Advantage II Cat

Experience the Benefits of Advantage II

Help stop the misery of biting fleas with Advantage II. This vet-recommended topical formula works to kill adult fleas as well as flea larvae and eggs, so your cat can focus on you. It only needs to be applied once a month and is for cats and kittens 8 weeks of age or older.

Why Choose Advantage II?

Advantage II is waterproof, fragrance-free and kills fleas directly through contact. That means pesky fleas dont have to bite to perish. It kills fleas within 12 hours of the first application and can protect against further infestation for up to a month. Best of all, with Advantage II, you can stop multiple flea life stages, to effectively break the flea life cycle.

Help Break the Flea Life Cycle

Immature fleas in a pet's environment consist of around 95% of an infestation and can be nearly invisible to the naked eye. That's why Advantage II has two active ingredients that work to stop fleas. The first active ingredient kills adult fleas by targeting their nervous system, while the second works as an insect growth regulator that kills flea eggs and larvae.

Is Advantage II the Right Choice for Your Cat?

Whether your cat is a winter sunspot-stealer or a summer backyard explorer, an sunseeker or an outdoor enthusiast, choose Advantage II to help keep fleas from interrupting his favorite activities year-round. If you want to return the love to your cat, take care of him with flea prevention that works to kill the fleas you see and the ones you don't.

Advantage II for Cats of All Sizes


2-5 pounds


5-9 pounds


Over 9 pounds

About Advantage II

Advantage II is manufactured by Bayer, a leading name in the healthcare industry for over 150 years. Advantage II is a veterinarian-recommended monthly flea treatment for your pet that kills fleas through contact. Targeting fleas, flea larvae and flea eggs, Advantage II is an effective treatment designed to provide dogs and cats with effective flea prevention that lasts all month.
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Questions & Answers

29 Customer Questions

Since the product is applied to your cats neck, what about the fleas on the cats belly will they move to the neck?
Answer by ChewySep 19, 2017
The active ingredients of Advantage II work to attack the fleas, no matter where they're located on your cat.

can you use before 30 days is up
Answer by ChewyMay 15, 2021
Under normal conditions this product is effective for one month. However, in cases of severe flea infestation, retreatment may be necessary earlier than 4 weeks. Do not retreat more often than once every 14 days for kittens or once every 7 days for small and large cats. After flea control is attained, return to a monthly retreatment schedule.

If my cat weighs about 9 lbs on the dot, which treatment should I use?
Answer by ChewyMay 24, 2019
If your cat weighs 9 pounds, it's recommended to use the Advantage II Flea Treatment for Small Cats 5 to 9 pounds. Use this treatment if they're over 9 pounds.

Do indoor cats need this?
Answer by ChewyMar 07, 2019
It is generally recommended to treat indoor pets. Fleas may be introduced into the home by coming in on another pet or even onto a person. If you are uncertain, we recommend consulting with your veterinarian who is familiar with flea information for your specific location.

ReviewsWrite a Review

Rated 4.2509 out of 5 stars
2463 Reviews
Would recommend to a friend

2463 Customer Reviews

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Rated 1 out of 5 stars
By KatieG on Jan 28, 2023

No Longer Works

I have been rotating flea treatments for my 3 cats since none seem to work anymore, it seems fleas have become resistant. I noticed a small improvement for 2-3 days after applying Advantage, then all 3 cats were scratching again like crazy. I am at my wits end and don't know if anything works anymore. I just ordered a different brand, hoping it works better than Advantage. All of them are pretty expensive, I wouldn't mind if one of them only worked. Sigh...

Rated 1 out of 5 stars
By catmom1 on Jan 20, 2023

not effective

i’ve tried using this product on/off for months now. every time i think it’s working and the fleas are finally gone, there’s always re-infestation. i’ve tried baths, treatment, nonstop cleaning, and thought i was finally seeing progress. these stopped working on our cats, so it’s time to keep looking for a solution that’ll actually work to keep the fleas gone and my cat babies comfortable.

Rated 1 out of 5 stars
By Babe on Jan 10, 2023

Does Not Work

This is the first time since 2006 that my dog and cat got fleas. One month ago applied this product. 2 weeks later she still has fleas. So I put another application on her. Still has them. We are going to the doggy doctor tomorrow to get a prescription cat flea medicine. I am out $50.00 on this product plus the $50.00 office visit tomorrow.

Rated 3 out of 5 stars
By Pepper on Jan 31, 2023

Formula becoming less effective

I have noticed that this formula has become less effective over the past 6 to 8 months. One treatment will now last about 2.5 weeks. I have used this brand on my cats and dog for years with great results. But now I will be looking for another product.

Rated 5 out of 5 stars
By Ctbabe12 on Feb 4, 2023

This stuff is great!

My vet recommended this product so I bought it and am very happy. However, this wasn't the first time. My cats aren't thrilled about getting it but again it works!

Rated 5 out of 5 stars
By Crabrielle on Nov 13, 2022

Great for indoor cats when you have a floater

Have 6 but only 2 go outside briefly a couple times a week. I give Revolution+ to the 2 who spend time outside for other parasites like ticks and mites, but give this to the indoor cats to keep them and the house flea free. Most importantly because I have an FIV cat with skin issues. Everyone seems to be doing well with this treatment and affordability is a major issue when you've taken in 6 cats.

Rated 4 out of 5 stars
By Jessi on Jan 28, 2023

Use on feral cats

I use on 2 big boy feral cats. However I do wish they would make flea & tick spot treatment for cats. Not just for Fleas.

Rated 3 out of 5 stars
By Lenny on Feb 3, 2023

Unknown to the quality

I can not imagine how justified it is to price the way its being done, without ending in changing with increase.

Rated 5 out of 5 stars
By judy on Nov 20, 2022

Such an easy way to shop

I am amazed at how easy it is to find what I need for my pet and get it delivered to my door. The service is amazingly easy and delivery is really fast. I've been using the repeat order service for cat food, and I never have to think about running out. Love it all.

Rated 1 out of 5 stars
By chris on Dec 16, 2022

Doesn't work like it used to

Been using this product off and on for years for both cats and ferrets. It has always worked wonders. However I have been battling fleas for the last 3 months iv been using this product and the fleas are only getting worse. Completely ineffective. I dont know what they changed but they need to change it back.