10 Best Cat Calmers 2025: According to Reviews | Chewy

The 10 Best Cat Calmers

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How we created this cat calmer list

We leveraged input from our veterinarians and artificial intelligence to identify key considerations to help you find the best cat calmer.
We scanned thousands of customer reviews and ratings and scored each product based on its performance against each of the key considerations. We then considered how popular a product is with Chewy customers and combined that with its key consideration scores to create the list of the best cat calmers.

Key cat calmer considerations

Duration of Effect

Ease of Use

Effectiveness

Ingredients

1
Feliway Classic Calming Diffuser Refill for Cats, 30 day, 1 count
Feliway Classic Calming Diffuser Refill for Cats, 30 day, 1 count
Feliway Classic Calming Diffuser Refill for Cats, 30 day, 1 count
Feliway Classic Calming Diffuser Refill for Cats, 30 day, 1 count
Feliway Classic Calming Diffuser Refill for Cats, 30 day, 1 count
Feliway Classic Calming Diffuser Refill for Cats, 30 day, 1 count
Feliway Classic Calming Diffuser Refill for Cats, 30 day, 1 count

Feliway Classic Calming Diffuser Refill for Cats, 30 day, 1 count

Rated 4.5 out of 5 stars
1,823
$20.99Chewy Price
($20.99/ea)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Duration of Effect

4.4/5
Great

Ease of Use

4.5/5
Great

Effectiveness

4.4/5
Great

Ingredients

4.3/5
Great

Is this cat calmer right for my pet?

Lifestage

All Lifestages, Adult

Top Ingredient

Analogue of Feline Facial Pheromone: 2%. Excipients to: 100g

Health Feature

Calming
2
Comfort Zone Multi-Cat Calming Pheromone Refills, pack of 6
Comfort Zone Multi-Cat Calming Pheromone Refills, pack of 6
Comfort Zone Multi-Cat Calming Pheromone Refills, pack of 6
Comfort Zone Multi-Cat Calming Pheromone Refills, pack of 6
Comfort Zone Multi-Cat Calming Pheromone Refills, pack of 6
Comfort Zone Multi-Cat Calming Pheromone Refills, pack of 6
Comfort Zone Multi-Cat Calming Pheromone Refills, pack of 6
Comfort Zone Multi-Cat Calming Pheromone Refills, pack of 6
Comfort Zone Multi-Cat Calming Pheromone Refills, pack of 6

Comfort Zone Multi-Cat Calming Pheromone Refills, pack of 6

Rated 4.5 out of 5 stars
1,102
$57.09Chewy Price
($9.52/ea)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Duration of Effect

4.4/5
Great

Ease of Use

4.4/5
Great

Effectiveness

4.4/5
Great

Ingredients

4.4/5
Great

Is this cat calmer right for my pet?

Lifestage

All Lifestages, Adult

Top Ingredient

Isoparaffinic Hydrocarbon (a petroleum distillate) 45.00% Analogue of Feline Pheromone 5.00% Other Ingredients 50.00%

Health Feature

Calming
3
Purina Pro Plan Veterinary Diets Calming Care Cat Supplement, 30 count
Purina Pro Plan Veterinary Diets Calming Care Cat Supplement, 30 count
Purina Pro Plan Veterinary Diets Calming Care Cat Supplement, 30 count
Purina Pro Plan Veterinary Diets Calming Care Cat Supplement, 30 count
Purina Pro Plan Veterinary Diets Calming Care Cat Supplement, 30 count
Purina Pro Plan Veterinary Diets Calming Care Cat Supplement, 30 count
Purina Pro Plan Veterinary Diets Calming Care Cat Supplement, 30 count
Purina Pro Plan Veterinary Diets Calming Care Cat Supplement, 30 count
Purina Pro Plan Veterinary Diets Calming Care Cat Supplement, 30 count

Purina Pro Plan Veterinary Diets Calming Care Cat Supplement, 30 count

Rated 4.3 out of 5 stars
1,016
$33.99Chewy Price
($1.14/ea)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Duration of Effect

4.3/5
Great

Ease of Use

4.3/5
Great

Effectiveness

4.3/5
Great

Ingredients

4.4/5
Great

Is this cat calmer right for my pet?

Breed Size

Small Breeds, Medium Breeds, Large Breeds

Lifestage

Adult, All Lifestages

Top Ingredients

Bifidobacterium Longum, Vitamin E, Liver Flavor, Maltodextrin

Food Flavor

Liver, Unflavored
4
Pet Honesty Dual Texture Chicken Flavored Calming Chews for Cats, 3.7-oz pouch
Pet Honesty Dual Texture Chicken Flavored Calming Chews for Cats, 3.7-oz pouch
Pet Honesty Dual Texture Chicken Flavored Calming Chews for Cats, 3.7-oz pouch
Pet Honesty Dual Texture Chicken Flavored Calming Chews for Cats, 3.7-oz pouch
Pet Honesty Dual Texture Chicken Flavored Calming Chews for Cats, 3.7-oz pouch
Pet Honesty Dual Texture Chicken Flavored Calming Chews for Cats, 3.7-oz pouch
Pet Honesty Dual Texture Chicken Flavored Calming Chews for Cats, 3.7-oz pouch
Pet Honesty Dual Texture Chicken Flavored Calming Chews for Cats, 3.7-oz pouch
Pet Honesty Dual Texture Chicken Flavored Calming Chews for Cats, 3.7-oz pouch

Pet Honesty Dual Texture Chicken Flavored Calming Chews for Cats, 3.7-oz pouch

Rated 4.1 out of 5 stars
1,519
$14.99Chewy Price
($4.06/oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Duration of Effect

4.2/5
Great

Ease of Use

4.3/5
Great

Effectiveness

4.3/5
Great

Ingredients

4.3/5
Great

Is this cat calmer right for my pet?

Breed Size

Small Breeds, Medium Breeds, Large Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Active Ingredients: Thiamine (Vitamin B1), L-Theanine, Chamomile , Inactive Ingredients: Thiamine (Vitamin B1), L-Theanine

Special Diet

Natural, No Corn No Wheat No Soy
5
Meowijuana Purrple Passion Catnip & Silvervine Blend Catnip, 0.917-oz bottle
Meowijuana Purrple Passion Catnip & Silvervine Blend Catnip, 0.917-oz bottle
Meowijuana Purrple Passion Catnip & Silvervine Blend Catnip, 0.917-oz bottle
Meowijuana Purrple Passion Catnip & Silvervine Blend Catnip, 0.917-oz bottle
Meowijuana Purrple Passion Catnip & Silvervine Blend Catnip, 0.917-oz bottle
Meowijuana Purrple Passion Catnip & Silvervine Blend Catnip, 0.917-oz bottle

Meowijuana Purrple Passion Catnip & Silvervine Blend Catnip, 0.917-oz bottle

Rated 4.4 out of 5 stars
403
$9.99Chewy Price
($10.90/oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Duration of Effect

4.2/5
Great

Ease of Use

4.4/5
Great

Effectiveness

4.2/5
Great

Ingredients

4.2/5
Great

Is this cat calmer right for my pet?

Lifestage

All Lifestages, Adult

Top Ingredient

Catnip and Silvervine

Material

Plant Material

Special Diet

Natural
6
Rescue Remedy Stress Relief Pet Supplement, 20-mL bottle
Rescue Remedy Stress Relief Pet Supplement, 20-mL bottle
Rescue Remedy Stress Relief Pet Supplement, 20-mL bottle
Rescue Remedy Stress Relief Pet Supplement, 20-mL bottle
Rescue Remedy Stress Relief Pet Supplement, 20-mL bottle
Rescue Remedy Stress Relief Pet Supplement, 20-mL bottle
Rescue Remedy Stress Relief Pet Supplement, 20-mL bottle

Rescue Remedy Stress Relief Pet Supplement, 20-mL bottle

Rated 4.1 out of 5 stars
1,517
$18.74Chewy Price
($0.94/mL)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Duration of Effect

4.2/5
Great

Ease of Use

4.3/5
Great

Effectiveness

4.2/5
Great

Ingredients

4.3/5
Great

Is this cat calmer right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

HPUS 5x Dilution of Helianthemum Nummularium, Clematis Vitalba, Impatiens Glandulifera, Prunus Cerasifera, Ornithogalum Umbellatum

Special Diet

Natural
7
Vetoquinol Zylkene 75-mg Capsules Calming Supplement for Small Dogs & Cats, 30 count
Vetoquinol Zylkene 75-mg Capsules Calming Supplement for Small Dogs & Cats, 30 count
Vetoquinol Zylkene 75-mg Capsules Calming Supplement for Small Dogs & Cats, 30 count
Vetoquinol Zylkene 75-mg Capsules Calming Supplement for Small Dogs & Cats, 30 count
Vetoquinol Zylkene 75-mg Capsules Calming Supplement for Small Dogs & Cats, 30 count

Vetoquinol Zylkene 75-mg Capsules Calming Supplement for Small Dogs & Cats, 30 count

Rated 4.1 out of 5 stars
710
$35.99Chewy Price
($1.20/ea)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Duration of Effect

4.1/5
Great

Ease of Use

4.1/5
Great

Effectiveness

4.2/5
Great

Ingredients

4.2/5
Great

Is this cat calmer right for my pet?

Breed Size

Small Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Active Ingredients: Hydrolized Milk Protein (Bovine), Inactive Ingredients: FD&C blue #1 (capsule), Hypromellose (capsule), Magnesium Stearate, Maltodextrin

Health Feature

Calming
8
Sentry Calming Chews Supplement for Cats, 4-oz bag
Sentry Calming Chews Supplement for Cats, 4-oz bag
Sentry Calming Chews Supplement for Cats, 4-oz bag
Sentry Calming Chews Supplement for Cats, 4-oz bag
Sentry Calming Chews Supplement for Cats, 4-oz bag
Sentry Calming Chews Supplement for Cats, 4-oz bag
Sentry Calming Chews Supplement for Cats, 4-oz bag

Sentry Calming Chews Supplement for Cats, 4-oz bag

Rated 4.2 out of 5 stars
531
$9.94Chewy Price
($2.49/oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Duration of Effect

4.2/5
Great

Ease of Use

4.3/5
Great

Effectiveness

4.1/5
Great

Ingredients

4.3/5
Great

Is this cat calmer right for my pet?

Lifestage

Adult, All Lifestages

Top Ingredients

Barley Flour, Brewers Dried Yeast, Brown Rice Flour, Chicken Fat, Chicken Meal

Special Diet

No Corn No Wheat No Soy

Food Flavor

Chicken
9
Feliway MultiCat Calming Diffuser Refill for Cats, 30 day, 1 count
Feliway MultiCat Calming Diffuser Refill for Cats, 30 day, 1 count
Feliway MultiCat Calming Diffuser Refill for Cats, 30 day, 1 count
Feliway MultiCat Calming Diffuser Refill for Cats, 30 day, 1 count
Feliway MultiCat Calming Diffuser Refill for Cats, 30 day, 1 count
Feliway MultiCat Calming Diffuser Refill for Cats, 30 day, 1 count
Feliway MultiCat Calming Diffuser Refill for Cats, 30 day, 1 count

Feliway MultiCat Calming Diffuser Refill for Cats, 30 day, 1 count

Rated 4.4 out of 5 stars
3,155
$20.99Chewy Price
($20.99/ea)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Duration of Effect

4.3/5
Great

Ease of Use

4.4/5
Great

Effectiveness

4.3/5
Great

Ingredients

4.2/5
Great

Is this cat calmer right for my pet?

Lifestage

All Lifestages, Adult

Top Ingredient

Analogue of Feline Facial Pheromone: 2%. Excipients to: 100g

Health Feature

Calming
10
HICC PET Gentle Antimicrobial Dog & Cat Eye Rinse, 5.1-fl oz bottle
HICC PET Gentle Antimicrobial Dog & Cat Eye Rinse, 5.1-fl oz bottle
HICC PET Gentle Antimicrobial Dog & Cat Eye Rinse, 5.1-fl oz bottle
HICC PET Gentle Antimicrobial Dog & Cat Eye Rinse, 5.1-fl oz bottle
HICC PET Gentle Antimicrobial Dog & Cat Eye Rinse, 5.1-fl oz bottle

HICC PET Gentle Antimicrobial Dog & Cat Eye Rinse, 5.1-fl oz bottle

Rated 4.8 out of 5 stars
53
$16.99Chewy Price
($3.34/fl oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Duration of Effect

4.2/5
Great

Ease of Use

4.5/5
Great

Effectiveness

4.6/5
Excellent

Ingredients

4.4/5
Great

Is this cat calmer right for my pet?

Breed Size

All Breeds

Lifestage

All Stages

Top Ingredient

Hypochlorous Acid (HOCl). Deionized Water

Health Feature

Eye Care, Allergy Relief, Tear Stain Removal, Sensitive Skin