10 Best Non-Prescription Cat Medications 2026: According to Reviews | Chewy

The 10 Best Non-Prescription Cat Medications

When minor issues come up, having the right products on hand can help you respond quickly and thoughtfully. Non-prescription cat medicine can support common concerns, from digestive upset to skin irritation. It's important to choose options with clear ingredients and directions, and to check with your veterinarian if symptoms persist or worsen. Below, you'll find today's top-rated non-prescription cat medicine that Chewy pet parents, like you, love. We update this list every week, so you can be sure you're getting the timeliest product recommendations available.

Our Top Picks

How we created this non-prescription cat medication list

We leveraged input from our veterinarians and artificial intelligence to identify key considerations to help you find the best non-prescription cat medication.
We scanned thousands of customer reviews and ratings and scored each product based on its performance against each of the key considerations. We then considered how popular a product is with Chewy customers and combined that with its key consideration scores to create the list of the best non-prescription cat medications.

Key non-prescription cat medication considerations

Ease of Use

Effectiveness

Ingredients

Side Effects

1
Greenies Pill Pockets Feline Chicken Flavor Natural Soft Adult Cat Treats, 3-oz bag, 85 count
Greenies Pill Pockets Feline Chicken Flavor Natural Soft Adult Cat Treats, 3-oz bag, 85 count
Greenies Pill Pockets Feline Chicken Flavor Natural Soft Adult Cat Treats, 3-oz bag, 85 count
Greenies Pill Pockets Feline Chicken Flavor Natural Soft Adult Cat Treats, 3-oz bag, 85 count
Greenies Pill Pockets Feline Chicken Flavor Natural Soft Adult Cat Treats, 3-oz bag, 85 count
Greenies Pill Pockets Feline Chicken Flavor Natural Soft Adult Cat Treats, 3-oz bag, 85 count
Greenies Pill Pockets Feline Chicken Flavor Natural Soft Adult Cat Treats, 3-oz bag, 85 count
Greenies Pill Pockets Feline Chicken Flavor Natural Soft Adult Cat Treats, 3-oz bag, 85 count
Greenies Pill Pockets Feline Chicken Flavor Natural Soft Adult Cat Treats, 3-oz bag, 85 count

Greenies Pill Pockets Feline Chicken Flavor Natural Soft Adult Cat Treats, 3-oz bag, 85 count

Rated 4.5 out of 5 stars
3,802
$10.97 Chewy Price
($3.66/oz)
Promo, New Customers Only: Spend $49+, get $20 eGift Card

Our ratings

Ease of Use

4.4/5
Great

Effectiveness

4.4/5
Great

Ingredients

4.4/5
Great

Side Effects

4.3/5
Great

Is this non-prescription cat medication right for my pet?

Lifestage

Adult

Top Ingredients

Chicken, Glycerin, Wheat Flour, Wheat Gluten, Vegetable Oil

Special Diet

Pea-Free, Indoor, Rawhide-Free, Natural

Food Flavor

Chicken, Poultry
2
Vetoquinol Pro-Pectalin Diarrhea Supplement for Dogs & Cats, 30-cc syringe
Vetoquinol Pro-Pectalin Diarrhea Supplement for Dogs & Cats, 30-cc syringe
Vetoquinol Pro-Pectalin Diarrhea Supplement for Dogs & Cats, 30-cc syringe
Vetoquinol Pro-Pectalin Diarrhea Supplement for Dogs & Cats, 30-cc syringe
Vetoquinol Pro-Pectalin Diarrhea Supplement for Dogs & Cats, 30-cc syringe
Vetoquinol Pro-Pectalin Diarrhea Supplement for Dogs & Cats, 30-cc syringe
Vetoquinol Pro-Pectalin Diarrhea Supplement for Dogs & Cats, 30-cc syringe
Vetoquinol Pro-Pectalin Diarrhea Supplement for Dogs & Cats, 30-cc syringe

Vetoquinol Pro-Pectalin Diarrhea Supplement for Dogs & Cats, 30-cc syringe

Rated 4.6 out of 5 stars
2,236
$24.29 Chewy Price
Promo, New Customers Only: Spend $49+, get $20 eGift Card

Our ratings

Ease of Use

4.5/5
Great

Effectiveness

4.5/5
Great

Ingredients

4.4/5
Great

Side Effects

4.3/5
Great

Is this non-prescription cat medication right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Active Per Ml: Kaolin 0.6 G, Pectin 0.025 G, Direct-Fed Microbials 0.2 Billion Cfu (Enterococcus Faecium) Kaolin, Soy Oil, Pectin

Health Feature

Digestive Health
3
HomeoPet UTI+ Homeopathic Medicine for Urinary Tract Infections UTI for Cats, 450 drops
HomeoPet UTI+ Homeopathic Medicine for Urinary Tract Infections UTI for Cats, 450 drops
HomeoPet UTI+ Homeopathic Medicine for Urinary Tract Infections UTI for Cats, 450 drops
HomeoPet UTI+ Homeopathic Medicine for Urinary Tract Infections UTI for Cats, 450 drops
HomeoPet UTI+ Homeopathic Medicine for Urinary Tract Infections UTI for Cats, 450 drops
HomeoPet UTI+ Homeopathic Medicine for Urinary Tract Infections UTI for Cats, 450 drops
HomeoPet UTI+ Homeopathic Medicine for Urinary Tract Infections UTI for Cats, 450 drops

HomeoPet UTI+ Homeopathic Medicine for Urinary Tract Infections UTI for Cats, 450 drops

Rated 4.4 out of 5 stars
1,326
$19.49 Chewy Price
Promo, New Customers Only: Spend $49+, get $20 eGift Card

Our ratings

Ease of Use

4.4/5
Great

Effectiveness

4.4/5
Great

Ingredients

4.3/5
Great

Side Effects

4.2/5
Great

Is this non-prescription cat medication right for my pet?

Lifestage

All Lifestages, Adult

Top Ingredients

Aconitum Napellus 200c, Apis Mellifica 6c, Argentum Nitricum 30c, Arnica Montana 6c, Arsenicum Album 6c

Special Diet

Natural

Health Feature

Urinary Tract Health
4
Lax-Aire Medication for Digestive Issues for Cats & Dogs, 3-oz tube
Lax-Aire Medication for Digestive Issues for Cats & Dogs, 3-oz tube
Lax-Aire Medication for Digestive Issues for Cats & Dogs, 3-oz tube

Lax-Aire Medication for Digestive Issues for Cats & Dogs, 3-oz tube

Rated 4.6 out of 5 stars
455
$19.57 Chewy Price
($6.53/oz)
Promo, New Customers Only: Spend $49+, get $20 eGift Card

Our ratings

Ease of Use

4.5/5
Great

Effectiveness

4.5/5
Great

Ingredients

4.4/5
Great

Side Effects

4.2/5
Great

Is this non-prescription cat medication right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Liquid Petrolatum, Cod Liver Oil, Soybean Oil, Peptonized Iron

Health Feature

Hairball Control, Digestive Health
5
Endosorb Medication for Digestive Issues & Diarrhea for Dogs & Cats, 1.5-g, 500 tablets
Endosorb Medication for Digestive Issues & Diarrhea for Dogs & Cats, 1.5-g, 500 tablets
Endosorb Medication for Digestive Issues & Diarrhea for Dogs & Cats, 1.5-g, 500 tablets
Endosorb Medication for Digestive Issues & Diarrhea for Dogs & Cats, 1.5-g, 500 tablets

Endosorb Medication for Digestive Issues & Diarrhea for Dogs & Cats, 1.5-g, 500 tablets

Rated 4.6 out of 5 stars
407
$125.85 Chewy Price
($0.26/ea)
Promo, New Customers Only: Spend $49+, get $20 eGift Card

Our ratings

Ease of Use

4.5/5
Great

Effectiveness

4.5/5
Great

Ingredients

4.4/5
Great

Side Effects

4.3/5
Great

Is this non-prescription cat medication right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Activated Attapulgite with Roasted Powdered Carob Pulp, Citrus Pectin, Magnesium Trisilicate, Colloidal Aluminum Silicate (Hydrated) with Artificial Color and Base

Health Feature

Digestive Health
6
MediNatura T-Relief Arnica +12 Homeopathic Medicine for Pain for Cats, Dogs & Horses, 90 count
MediNatura T-Relief Arnica +12 Homeopathic Medicine for Pain for Cats, Dogs & Horses, 90 count
MediNatura T-Relief Arnica +12 Homeopathic Medicine for Pain for Cats, Dogs & Horses, 90 count
MediNatura T-Relief Arnica +12 Homeopathic Medicine for Pain for Cats, Dogs & Horses, 90 count
MediNatura T-Relief Arnica +12 Homeopathic Medicine for Pain for Cats, Dogs & Horses, 90 count

MediNatura T-Relief Arnica +12 Homeopathic Medicine for Pain for Cats, Dogs & Horses, 90 count

Rated 4.5 out of 5 stars
580
$18.99 Chewy Price
($0.22/ea)
Promo, New Customers Only: Spend $49+, get $20 eGift Card

Our ratings

Ease of Use

4.4/5
Great

Effectiveness

4.4/5
Great

Ingredients

4.4/5
Great

Side Effects

4.3/5
Great

Is this non-prescription cat medication right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Active Ingredients: Each Tablet Contains: Arnica Montana 3X 150mg, Calendula Officinalis 2X 10mg, Hamamelis Virginiana 2X 10mg, Baptisia Tinctoria 2X 6mg, Bellis Perennis 2X 6mg

Special Diet

Natural
7
Tomlyn Pill-Masker, 4-oz jar
Tomlyn Pill-Masker, 4-oz jar
Tomlyn Pill-Masker, 4-oz jar
Tomlyn Pill-Masker, 4-oz jar
Tomlyn Pill-Masker, 4-oz jar

Tomlyn Pill-Masker, 4-oz jar

Rated 4.1 out of 5 stars
1,005
$13.99 Chewy Price
($3.50/oz)
Promo, New Customers Only: Spend $49+, get $20 eGift Card

Our ratings

Ease of Use

4.3/5
Great

Effectiveness

4.4/5
Great

Ingredients

4.3/5
Great

Side Effects

4.3/5
Great

Is this non-prescription cat medication right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Wheat Flour, Corn Syrup, Glycerin, Vegetable Oil, Stabilized Rice Bran

Food Flavor

Bacon, Meat
8
Medline Pill Splitter
Medline Pill Splitter
Medline Pill Splitter
Medline Pill Splitter
Medline Pill Splitter

Medline Pill Splitter

Rated 4.4 out of 5 stars
507
$5.79 Chewy Price
($5.79/ea)
Promo, Save 50% today with Autoship , Up To $50 Off

Our ratings

Ease of Use

4.5/5
Great

Effectiveness

4.5/5
Great

Ingredients

4.4/5
Great

Side Effects

4.3/5
Great

Is this non-prescription cat medication right for my pet?

Breed Size

Extra Small Breeds, Small Breeds, Medium Breeds, Large Breeds...

Material

Plastic
9
Van Beek Natural Science Diagel for Digestive Issues for Cats, 1-ml
Van Beek Natural Science Diagel for Digestive Issues for Cats, 1-ml

Van Beek Natural Science Diagel for Digestive Issues for Cats, 1-ml

Rated 4.7 out of 5 stars
74
$26.36 Chewy Price
Promo, New Customers Only: Spend $49+, get $20 eGift Card

Our ratings

Ease of Use

4.6/5
Excellent

Effectiveness

4.6/5
Excellent

Ingredients

4.5/5
Great

Side Effects

4.4/5
Great

Is this non-prescription cat medication right for my pet?

Lifestage

Kitten

Top Ingredients

Active Ingredients: Chamazulene., Inactive Ingredients: Carob, Cranberry Powder, Microencapsulated Bead Agents, Miglyol

Special Diet

Natural

Health Feature

Digestive Health
10
Natura Petz Organics Break It Up! Herbal Medicine for Bladder Stones & Kidney Stones for Cats, 90 count
Natura Petz Organics Break It Up! Herbal Medicine for Bladder Stones & Kidney Stones for Cats, 90 count
Natura Petz Organics Break It Up! Herbal Medicine for Bladder Stones & Kidney Stones for Cats, 90 count
Natura Petz Organics Break It Up! Herbal Medicine for Bladder Stones & Kidney Stones for Cats, 90 count

Natura Petz Organics Break It Up! Herbal Medicine for Bladder Stones & Kidney Stones for Cats, 90 count

Rated 4.5 out of 5 stars
247
$29.99 Chewy Price
($0.34/ea)
Promo, New Customers Only: Spend $49+, get $20 eGift Card

Our ratings

Ease of Use

4.3/5
Great

Effectiveness

4.4/5
Great

Ingredients

4.3/5
Great

Side Effects

4.1/5
Great

Is this non-prescription cat medication right for my pet?

Lifestage

All Lifestages, Adult

Top Ingredients

Gelatin Capsules, Chanca Piedra Stone Breaker, Berenjena, Potato Extract, Cipo Cabeludo

Special Diet

Organic, No Corn No Wheat No Soy

Food Flavor

Turkey, Poultry