10 Best Medicated Shampoos for Cats 2025: According to Reviews | Chewy

The 10 Best Medicated Shampoos for Cats

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How we created this medicated shampoo list

We leveraged input from our veterinarians and artificial intelligence to identify key considerations to help you find the best medicated shampoos for cat.
We scanned thousands of customer reviews and ratings and scored each product based on its performance against each of the key considerations. We then considered how popular a product is with Chewy customers and combined that with its key consideration scores to create the list of the best medicated shampoos for cats.

Key medicated shampoo considerations

Active Ingredients

Ease of Use

Effectiveness

Safety

1
Zymox Otic Dog & Cat Ear Infection Treatment with Hydrocortisone, 1.25-fl oz bottle
Zymox Otic Dog & Cat Ear Infection Treatment with Hydrocortisone, 1.25-fl oz bottle
Zymox Otic Dog & Cat Ear Infection Treatment with Hydrocortisone, 1.25-fl oz bottle
Zymox Otic Dog & Cat Ear Infection Treatment with Hydrocortisone, 1.25-fl oz bottle
Zymox Otic Dog & Cat Ear Infection Treatment with Hydrocortisone, 1.25-fl oz bottle
Zymox Otic Dog & Cat Ear Infection Treatment with Hydrocortisone, 1.25-fl oz bottle
Zymox Otic Dog & Cat Ear Infection Treatment with Hydrocortisone, 1.25-fl oz bottle
Zymox Otic Dog & Cat Ear Infection Treatment with Hydrocortisone, 1.25-fl oz bottle
Zymox Otic Dog & Cat Ear Infection Treatment with Hydrocortisone, 1.25-fl oz bottle

Zymox Otic Dog & Cat Ear Infection Treatment with Hydrocortisone, 1.25-fl oz bottle

Rated 4.8 out of 5 stars
5,515
$23.79Chewy Price
($19.04/fl oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Active Ingredients

4.5/5
Great

Ease of Use

4.6/5
Excellent

Effectiveness

4.6/5
Excellent

Safety

4.5/5
Great

Is this medicated shampoo right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Active Ingredients: Hydrocortisone 1%., Inactive Ingredients: Benzyl Alcohol, Dextrose, Glucose Oxidase, Glycerin

Health Feature

Ear Care
2
Virbac Epi-Otic Advanced Ear Cleaner for Dogs & Cats, 8-fl oz bottle
Virbac Epi-Otic Advanced Ear Cleaner for Dogs & Cats, 8-fl oz bottle
Virbac Epi-Otic Advanced Ear Cleaner for Dogs & Cats, 8-fl oz bottle
Virbac Epi-Otic Advanced Ear Cleaner for Dogs & Cats, 8-fl oz bottle
Virbac Epi-Otic Advanced Ear Cleaner for Dogs & Cats, 8-fl oz bottle

Virbac Epi-Otic Advanced Ear Cleaner for Dogs & Cats, 8-fl oz bottle

Rated 4.7 out of 5 stars
3,392
$21.39Chewy Price
($2.68/fl oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Active Ingredients

4.5/5
Great

Ease of Use

4.6/5
Excellent

Effectiveness

4.6/5
Excellent

Safety

4.5/5
Great

Is this medicated shampoo right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Water, ethoxydiglycol, PEG-40 hydrogenated castor oil, disodium EDTA, docusate sodium

Health Feature

Ear Care
3
Douxo S3 PYO Antiseptic Antifungal Chlorhexidine Dog & Cat Wipes 30 count
Douxo S3 PYO Antiseptic Antifungal Chlorhexidine Dog & Cat Wipes 30 count
Douxo S3 PYO Antiseptic Antifungal Chlorhexidine Dog & Cat Wipes 30 count
Douxo S3 PYO Antiseptic Antifungal Chlorhexidine Dog & Cat Wipes 30 count
Douxo S3 PYO Antiseptic Antifungal Chlorhexidine Dog & Cat Wipes 30 count
Douxo S3 PYO Antiseptic Antifungal Chlorhexidine Dog & Cat Wipes 30 count

Douxo S3 PYO Antiseptic Antifungal Chlorhexidine Dog & Cat Wipes 30 count

Rated 4.7 out of 5 stars
1,879
$18.99Chewy Price
($0.64/ea)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Active Ingredients

4.6/5
Excellent

Ease of Use

4.6/5
Excellent

Effectiveness

4.6/5
Excellent

Safety

4.5/5
Great

Is this medicated shampoo right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Ophytrium, Chlorhexidine

Health Feature

Anti-Fungal / Anti-Bacterial
4
MiconaHex+Triz Shampoo for Dogs & Cats, 16-fl oz bottle
MiconaHex+Triz Shampoo for Dogs & Cats, 16-fl oz bottle
MiconaHex+Triz Shampoo for Dogs & Cats, 16-fl oz bottle
MiconaHex+Triz Shampoo for Dogs & Cats, 16-fl oz bottle
MiconaHex+Triz Shampoo for Dogs & Cats, 16-fl oz bottle
MiconaHex+Triz Shampoo for Dogs & Cats, 16-fl oz bottle

MiconaHex+Triz Shampoo for Dogs & Cats, 16-fl oz bottle

Rated 4.7 out of 5 stars
1,749
$43.90Chewy Price
($2.75/fl oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Active Ingredients

4.5/5
Great

Ease of Use

4.5/5
Great

Effectiveness

4.5/5
Great

Safety

4.4/5
Great

Is this medicated shampoo right for my pet?

Lifestage

All Lifestages, Adult

Top Ingredients

Active Ingredients: 2% Miconazole Nitrate USP, 2% Chlorhexidine Gluconate USP, USP tris-EDTA

Health Feature

Itch & Redness Remedy, Skin & Coat Health, Anti-Fungal / Anti-Bacterial
5
Musher's Secret Paw Protection Natural Dog Wax, 60-g jar
Musher's Secret Paw Protection Natural Dog Wax, 60-g jar
Musher's Secret Paw Protection Natural Dog Wax, 60-g jar
Musher's Secret Paw Protection Natural Dog Wax, 60-g jar
Musher's Secret Paw Protection Natural Dog Wax, 60-g jar

Musher's Secret Paw Protection Natural Dog Wax, 60-g jar

Rated 4.7 out of 5 stars
2,243
$15.99Chewy Price
($0.27/g)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Active Ingredients

4.7/5
Excellent

Ease of Use

4.6/5
Excellent

Effectiveness

4.6/5
Excellent

Safety

4.6/5
Excellent

Is this medicated shampoo right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

White and Yellow Beeswax, Carnauba, and Candelilla Wax and White and Vegetable Oils with Vitamin E

Health Feature

Itch & Redness Remedy, Paw Care, Hoof Care
6
Veterinary Formula Clinical Care Antiseptic & Antifungal Medicated Spray, 8-fl oz spray
Veterinary Formula Clinical Care Antiseptic & Antifungal Medicated Spray, 8-fl oz spray
Veterinary Formula Clinical Care Antiseptic & Antifungal Medicated Spray, 8-fl oz spray
Veterinary Formula Clinical Care Antiseptic & Antifungal Medicated Spray, 8-fl oz spray
Veterinary Formula Clinical Care Antiseptic & Antifungal Medicated Spray, 8-fl oz spray
Veterinary Formula Clinical Care Antiseptic & Antifungal Medicated Spray, 8-fl oz spray
Veterinary Formula Clinical Care Antiseptic & Antifungal Medicated Spray, 8-fl oz spray
Veterinary Formula Clinical Care Antiseptic & Antifungal Medicated Spray, 8-fl oz spray

Veterinary Formula Clinical Care Antiseptic & Antifungal Medicated Spray, 8-fl oz spray

Rated 4.5 out of 5 stars
1,271
$8.99Chewy Price
($1.13/fl oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Active Ingredients

4.4/5
Great

Ease of Use

4.4/5
Great

Effectiveness

4.5/5
Great

Safety

4.3/5
Great

Is this medicated shampoo right for my pet?

Breed Size

Small Breeds, Medium Breeds, Large Breeds, Extra Small Breeds...

Lifestage

All Lifestages, Adult

Top Ingredients

Purified Water, Glycerin USP, Keratin, Poly-sorbate -20, Fragrance

Health Feature

Itch & Redness Remedy, Skin & Coat Health
7
Malaseb Shampoo for Dogs, Cats & Horses, 16-fl oz bottle

Malaseb Shampoo for Dogs, Cats & Horses, 16-fl oz bottle

Rated 4.8 out of 5 stars
511
$44.00Chewy Price
($2.75/fl oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Active Ingredients

4.7/5
Excellent

Ease of Use

4.6/5
Excellent

Effectiveness

4.7/5
Excellent

Safety

4.5/5
Great

Is this medicated shampoo right for my pet?

Lifestage

All Lifestages

Top Ingredients

Also Contains: Water, Decyl Polyglucoside, Cetrimonium Chloride, Laureth-12, PEG-120 Methyl Glucose Dioleate

Health Feature

Anti-Fungal / Anti-Bacterial
8
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Cat & Dog Shampoo, 16-fl oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Cat & Dog Shampoo, 16-fl oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Cat & Dog Shampoo, 16-fl oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Cat & Dog Shampoo, 16-fl oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Cat & Dog Shampoo, 16-fl oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Cat & Dog Shampoo, 16-fl oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Cat & Dog Shampoo, 16-fl oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Cat & Dog Shampoo, 16-fl oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Cat & Dog Shampoo, 16-fl oz bottle

Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Cat & Dog Shampoo, 16-fl oz bottle

Rated 4.7 out of 5 stars
563
$23.99Chewy Price
($1.50/fl oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Active Ingredients

4.6/5
Excellent

Ease of Use

4.4/5
Great

Effectiveness

4.5/5
Great

Safety

4.3/5
Great

Is this medicated shampoo right for my pet?

Breed Size

Small Breeds, Medium Breeds, Large Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Chlorhexidine Gluconate, Ketoconazole, Water, Lauramine Oxide, Polyacrylate-1 Crosspolymer

Health Feature

Anti-Fungal / Anti-Bacterial, Itch & Redness Remedy
9
TrizCHLOR 4 Shampoo for Dogs, Cats & Horses, 8-fl oz bottle
TrizCHLOR 4 Shampoo for Dogs, Cats & Horses, 8-fl oz bottle
TrizCHLOR 4 Shampoo for Dogs, Cats & Horses, 8-fl oz bottle
TrizCHLOR 4 Shampoo for Dogs, Cats & Horses, 8-fl oz bottle
TrizCHLOR 4 Shampoo for Dogs, Cats & Horses, 8-fl oz bottle
TrizCHLOR 4 Shampoo for Dogs, Cats & Horses, 8-fl oz bottle

TrizCHLOR 4 Shampoo for Dogs, Cats & Horses, 8-fl oz bottle

Rated 4.7 out of 5 stars
421
$20.52Chewy Price
($2.57/fl oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Active Ingredients

4.7/5
Excellent

Ease of Use

4.6/5
Excellent

Effectiveness

4.6/5
Excellent

Safety

4.5/5
Great

Is this medicated shampoo right for my pet?

Lifestage

All Lifestages, Adult

Top Ingredients

Active: 4% Chlorhexidene Gluconate, Trizedta (Tromethamine USP, Disodium Edta Dihydrate). Also Contains: Lauramine Oxide, Cocamidopropyl Betaine, Super Cocamide

Health Feature

Itch & Redness Remedy, Skin & Coat Health, Anti-Fungal / Anti-Bacterial
10
DermaBenSs Shampoo for Dogs, Cats & Horses, 12-fl oz bottle
DermaBenSs Shampoo for Dogs, Cats & Horses, 12-fl oz bottle
DermaBenSs Shampoo for Dogs, Cats & Horses, 12-fl oz bottle
DermaBenSs Shampoo for Dogs, Cats & Horses, 12-fl oz bottle
DermaBenSs Shampoo for Dogs, Cats & Horses, 12-fl oz bottle
DermaBenSs Shampoo for Dogs, Cats & Horses, 12-fl oz bottle

DermaBenSs Shampoo for Dogs, Cats & Horses, 12-fl oz bottle

Rated 4.7 out of 5 stars
336
$23.85Chewy Price
($1.99/fl oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Active Ingredients

4.6/5
Excellent

Ease of Use

4.6/5
Excellent

Effectiveness

4.6/5
Excellent

Safety

4.5/5
Great

Is this medicated shampoo right for my pet?

Lifestage

All Lifestages, Adult

Top Ingredients

Active: 2.5% Benzoyl Peroxide, 1% Sodium Thiosulfate, 1% Salicylic Acid, Ceramides. Inactive: Propylene Glycol, Fragrance

Health Feature

Itch & Redness Remedy, Anti-Fungal / Anti-Bacterial