10 Best Home Flea & Tick Treatment for Cats 2025: According to Reviews | Chewy

The 10 Best Home Flea & Tick Treatment for Cats

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How we created this home flea & tick treatment list

We leveraged input from our veterinarians and artificial intelligence to identify key considerations to help you find the best home flea & tick treatment for cat.
We scanned thousands of customer reviews and ratings and scored each product based on its performance against each of the key considerations. We then considered how popular a product is with Chewy customers and combined that with its key consideration scores to create the list of the best home flea & tick treatment for cats.

Key home flea & tick treatment considerations

Duration of Protection

Ease of Application

Effectiveness

Safety

1
Virbac Knockout E.S. Area Treatment Spray, 16-fl oz can
Virbac Knockout E.S. Area Treatment Spray, 16-fl oz can
Virbac Knockout E.S. Area Treatment Spray, 16-fl oz can
Virbac Knockout E.S. Area Treatment Spray, 16-fl oz can
Virbac Knockout E.S. Area Treatment Spray, 16-fl oz can

Virbac Knockout E.S. Area Treatment Spray, 16-fl oz can

Rated 4.5 out of 5 stars
420
$32.29Chewy Price
($2.02/fl oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Duration of Protection

4.5/5
Great

Ease of Application

4.6/5
Excellent

Effectiveness

4.4/5
Great

Safety

4.1/5
Great

Is this home flea & tick treatment right for my pet?

Breed Size

Small Breeds, Medium Breeds, Large Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Pyriproxyfen .10%, Pyrethrins, a botanical insecticide .05%, n-Octyl bicycloheptene dicarboximide* .40%, Permethrin .40%
2
Wondercide Natural Flea, Tick & Mosquito Spray for Dogs & Cats, Lemongrass, 16-fl oz bottle
Wondercide Natural Flea, Tick & Mosquito Spray for Dogs & Cats, Lemongrass, 16-fl oz bottle
Wondercide Natural Flea, Tick & Mosquito Spray for Dogs & Cats, Lemongrass, 16-fl oz bottle
Wondercide Natural Flea, Tick & Mosquito Spray for Dogs & Cats, Lemongrass, 16-fl oz bottle
Wondercide Natural Flea, Tick & Mosquito Spray for Dogs & Cats, Lemongrass, 16-fl oz bottle
Wondercide Natural Flea, Tick & Mosquito Spray for Dogs & Cats, Lemongrass, 16-fl oz bottle
Wondercide Natural Flea, Tick & Mosquito Spray for Dogs & Cats, Lemongrass, 16-fl oz bottle
Wondercide Natural Flea, Tick & Mosquito Spray for Dogs & Cats, Lemongrass, 16-fl oz bottle

Wondercide Natural Flea, Tick & Mosquito Spray for Dogs & Cats, Lemongrass, 16-fl oz bottle

Rated 4.1 out of 5 stars
424
$26.99Chewy Price
($1.69/fl oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Duration of Protection

4.3/5
Great

Ease of Application

4.2/5
Great

Effectiveness

4.4/5
Great

Safety

4.1/5
Great

Is this home flea & tick treatment right for my pet?

Breed Size

All Breeds

Lifestage

Adult, All Lifestages

Top Ingredients

Active Ingredients: 4.2% Cedarwood Oil, 2.2% Sodium Lauryl Sulfate, 1.5% Lemongrass Oil, 0.1% Sesame Oil., Inactive Ingredients: Water

Health Feature

Pest Control
3
PetArmor Home & Carpet Spray Fresh Scent for Pets, 16-fl oz bottle
PetArmor Home & Carpet Spray Fresh Scent for Pets, 16-fl oz bottle
PetArmor Home & Carpet Spray Fresh Scent for Pets, 16-fl oz bottle
PetArmor Home & Carpet Spray Fresh Scent for Pets, 16-fl oz bottle
PetArmor Home & Carpet Spray Fresh Scent for Pets, 16-fl oz bottle
PetArmor Home & Carpet Spray Fresh Scent for Pets, 16-fl oz bottle

PetArmor Home & Carpet Spray Fresh Scent for Pets, 16-fl oz bottle

Rated 4.5 out of 5 stars
167
$7.51Chewy Price
($0.47/fl oz)

Our ratings

Duration of Protection

4.3/5
Great

Ease of Application

4.4/5
Great

Effectiveness

4.4/5
Great

Safety

4.3/5
Great

Is this home flea & tick treatment right for my pet?

Lifestage

All Lifestages, Adult

Top Ingredients

3-phenoxybenzyl-(1RS, 3RS, 1RS, 3SR)-2, 2-dimethyl-3-(2-methylprop-1-enyl) cyclopropanecarboxylate

Health Feature

Pest Control, Anti-Parasitic
4
Advantage Household Spot & Crevice Spray, 24-fl oz spray
Advantage Household Spot & Crevice Spray, 24-fl oz spray
Advantage Household Spot & Crevice Spray, 24-fl oz spray
Advantage Household Spot & Crevice Spray, 24-fl oz spray
Advantage Household Spot & Crevice Spray, 24-fl oz spray
Advantage Household Spot & Crevice Spray, 24-fl oz spray
Advantage Household Spot & Crevice Spray, 24-fl oz spray

Advantage Household Spot & Crevice Spray, 24-fl oz spray

Rated 4.7 out of 5 stars
116
$20.98Chewy Price
($0.88/fl oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Duration of Protection

4.0/5
Great

Ease of Application

4.2/5
Great

Effectiveness

4.4/5
Great

Safety

4.1/5
Great

Is this home flea & tick treatment right for my pet?

Lifestage

All Lifestages, Adult

Top Ingredients

Active Ingredients: 0.40% Sumithrin, 1.00% mgk 264 Insecticide Synergist, 0.05% Imidacloprid
5
Fleabusters RX for Fleas Plus Powder, 3-lb jar
Fleabusters RX for Fleas Plus Powder, 3-lb jar
Fleabusters RX for Fleas Plus Powder, 3-lb jar

Fleabusters RX for Fleas Plus Powder, 3-lb jar

Rated 4 out of 5 stars
178
$36.48Chewy Price
($12.16/lb)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Duration of Protection

4.2/5
Great

Ease of Application

4.4/5
Great

Effectiveness

4.3/5
Great

Safety

4.2/5
Great

Is this home flea & tick treatment right for my pet?

Lifestage

All Lifestages, Adult

Top Ingredient

Active Ingredients: Orthoboric Acid 64.00% Inert Ingredients: 36.00%

Health Feature

Anti-Parasitic
6
Hartz Nature's Shield Natural Flea & Tick Home Spray
Hartz Nature's Shield Natural Flea & Tick Home Spray
Hartz Nature's Shield Natural Flea & Tick Home Spray
Hartz Nature's Shield Natural Flea & Tick Home Spray
Hartz Nature's Shield Natural Flea & Tick Home Spray
Hartz Nature's Shield Natural Flea & Tick Home Spray
Hartz Nature's Shield Natural Flea & Tick Home Spray

Hartz Nature's Shield Natural Flea & Tick Home Spray

Rated 4.2 out of 5 stars
271
$9.98Chewy Price
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Duration of Protection

4.0/5
Great

Ease of Application

4.1/5
Great

Effectiveness

4.1/5
Great

Safety

4.1/5
Great

Is this home flea & tick treatment right for my pet?

Lifestage

All Lifestages, Adult

Top Ingredients

Lemongrass Oil, Cedarwood Oil, Sodium Lauryl Sulfate

Health Feature

Anti-Parasitic, Pest Control
7
Adams Flea & Tick Carpet Powder, 16-oz bottle
Adams Flea & Tick Carpet Powder, 16-oz bottle
Adams Flea & Tick Carpet Powder, 16-oz bottle
Adams Flea & Tick Carpet Powder, 16-oz bottle
Adams Flea & Tick Carpet Powder, 16-oz bottle
Adams Flea & Tick Carpet Powder, 16-oz bottle
Adams Flea & Tick Carpet Powder, 16-oz bottle
Adams Flea & Tick Carpet Powder, 16-oz bottle

Adams Flea & Tick Carpet Powder, 16-oz bottle

Rated 4 out of 5 stars
202
$11.12Chewy Price
($0.70/oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Duration of Protection

3.8/5
Good

Ease of Application

4.1/5
Great

Effectiveness

4.4/5
Great

Safety

4.3/5
Great

Is this home flea & tick treatment right for my pet?

Lifestage

All Lifestages, Adult

Top Ingredients

LiN/Alool 2.500%, Piperonyl Butoxide 0.500%, Pyrethrins 0.075%, Pyriproxyfen 0.020%, OTHER INGREDIENTS: 96.905%

Health Feature

Pest Control
8
Flea Away Diatomaceous Earth for Dogs & Cat, 12-oz jar
Flea Away Diatomaceous Earth for Dogs & Cat, 12-oz jar

Flea Away Diatomaceous Earth for Dogs & Cat, 12-oz jar

Rated 4.1 out of 5 stars
166
$15.99Chewy Price
($1.34/oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Duration of Protection

3.9/5
Good

Ease of Application

4.2/5
Great

Effectiveness

3.8/5
Good

Safety

4.1/5
Great

Is this home flea & tick treatment right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Active Ingredients: Silicon Dioxide (Max.) - 85%, Other Elemental Oxides (Max.) - 10%, Moisture (Max.) - 12%
9
Virbac Knockout Area Treatment Spray, 14-fl oz can
Virbac Knockout Area Treatment Spray, 14-fl oz can
Virbac Knockout Area Treatment Spray, 14-fl oz can
Virbac Knockout Area Treatment Spray, 14-fl oz can
Virbac Knockout Area Treatment Spray, 14-fl oz can

Virbac Knockout Area Treatment Spray, 14-fl oz can

Rated 4.3 out of 5 stars
173
$23.79Chewy Price
($1.70/fl oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Duration of Protection

4.2/5
Great

Ease of Application

4.3/5
Great

Effectiveness

4.2/5
Great

Safety

4.5/5
Great

Is this home flea & tick treatment right for my pet?

Lifestage

All Lifestages, Adult

Top Ingredients

Pyriproxyfen .015%, Tetramethrin .400%, Phenothrin .300%, Other Ingredients 99.285%
10
Cedarcide Cedarwood All-Purpose Dog & Cat Bug Spray, 32-fl oz bottle
Cedarcide Cedarwood All-Purpose Dog & Cat Bug Spray, 32-fl oz bottle
Cedarcide Cedarwood All-Purpose Dog & Cat Bug Spray, 32-fl oz bottle
Cedarcide Cedarwood All-Purpose Dog & Cat Bug Spray, 32-fl oz bottle

Cedarcide Cedarwood All-Purpose Dog & Cat Bug Spray, 32-fl oz bottle

Rated 4.1 out of 5 stars
64
$24.00Chewy Price
($0.75/fl oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Duration of Protection

4.0/5
Great

Ease of Application

4.2/5
Great

Effectiveness

4.1/5
Great

Safety

3.8/5
Good

Is this home flea & tick treatment right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Inactive: Water, Glycerin, Polyglyceryl Oleate, Sodium Citrate