10 Best Home Flea & Tick Treatment for Dogs 2025: According to Reviews | Chewy

The 10 Best Home Flea & Tick Treatment for Dogs

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How we created this home flea & tick treatment list

We leveraged input from our veterinarians and artificial intelligence to identify key considerations to help you find the best home flea & tick treatment for dog.
We scanned thousands of customer reviews and ratings and scored each product based on its performance against each of the key considerations. We then considered how popular a product is with Chewy customers and combined that with its key consideration scores to create the list of the best home flea & tick treatment for dogs.

Key home flea & tick treatment considerations

Duration of Protection

Ease of Use

Effectiveness

Safety

1
Virbac Knockout E.S. Area Treatment Spray, 16-fl oz can
Virbac Knockout E.S. Area Treatment Spray, 16-fl oz can
Virbac Knockout E.S. Area Treatment Spray, 16-fl oz can
Virbac Knockout E.S. Area Treatment Spray, 16-fl oz can
Virbac Knockout E.S. Area Treatment Spray, 16-fl oz can

Virbac Knockout E.S. Area Treatment Spray, 16-fl oz can

Rated 4.5 out of 5 stars
416
$32.29Chewy Price
($2.02/fl oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Duration of Protection

4.5/5
Great

Ease of Use

4.4/5
Great

Effectiveness

4.3/5
Great

Safety

4.1/5
Great

Is this home flea & tick treatment right for my pet?

Breed Size

Small Breeds, Medium Breeds, Large Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Pyriproxyfen .10%, Pyrethrins, a botanical insecticide .05%, n-Octyl bicycloheptene dicarboximide* .40%, Permethrin .40%
2
Wondercide Natural Flea, Tick & Mosquito Spray for Dogs & Cats, Lemongrass, 16-fl oz bottle
Wondercide Natural Flea, Tick & Mosquito Spray for Dogs & Cats, Lemongrass, 16-fl oz bottle
Wondercide Natural Flea, Tick & Mosquito Spray for Dogs & Cats, Lemongrass, 16-fl oz bottle
Wondercide Natural Flea, Tick & Mosquito Spray for Dogs & Cats, Lemongrass, 16-fl oz bottle
Wondercide Natural Flea, Tick & Mosquito Spray for Dogs & Cats, Lemongrass, 16-fl oz bottle
Wondercide Natural Flea, Tick & Mosquito Spray for Dogs & Cats, Lemongrass, 16-fl oz bottle
Wondercide Natural Flea, Tick & Mosquito Spray for Dogs & Cats, Lemongrass, 16-fl oz bottle
Wondercide Natural Flea, Tick & Mosquito Spray for Dogs & Cats, Lemongrass, 16-fl oz bottle

Wondercide Natural Flea, Tick & Mosquito Spray for Dogs & Cats, Lemongrass, 16-fl oz bottle

Rated 4.1 out of 5 stars
417
$26.99Chewy Price
($1.69/fl oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Duration of Protection

4.2/5
Great

Ease of Use

4.3/5
Great

Effectiveness

4.4/5
Great

Safety

4.2/5
Great

Is this home flea & tick treatment right for my pet?

Breed Size

All Breeds

Lifestage

Adult, All Lifestages

Top Ingredients

Active Ingredients: 4.2% Cedarwood Oil, 2.2% Sodium Lauryl Sulfate, 1.5% Lemongrass Oil, 0.1% Sesame Oil., Inactive Ingredients: Water

Health Feature

Pest Control
3
First Saturday Lime Monthly Pet Insect Repellent, 5-lb bag
First Saturday Lime Monthly Pet Insect Repellent, 5-lb bag
First Saturday Lime Monthly Pet Insect Repellent, 5-lb bag
First Saturday Lime Monthly Pet Insect Repellent, 5-lb bag
First Saturday Lime Monthly Pet Insect Repellent, 5-lb bag
First Saturday Lime Monthly Pet Insect Repellent, 5-lb bag
First Saturday Lime Monthly Pet Insect Repellent, 5-lb bag
First Saturday Lime Monthly Pet Insect Repellent, 5-lb bag

First Saturday Lime Monthly Pet Insect Repellent, 5-lb bag

Rated 4.6 out of 5 stars
315
$27.99Chewy Price
($5.60/lb)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Duration of Protection

4.3/5
Great

Ease of Use

4.5/5
Great

Effectiveness

4.3/5
Great

Safety

4.4/5
Great

Is this home flea & tick treatment right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Citric Acid, Calcite

Farm Animal Type

Poultry
4
Vet's Best Indoor Flea & Tick Home Spray Refill for Dogs, 32-fl oz bottle
Vet's Best Indoor Flea & Tick Home Spray Refill for Dogs, 32-fl oz bottle
Vet's Best Indoor Flea & Tick Home Spray Refill for Dogs, 32-fl oz bottle
Vet's Best Indoor Flea & Tick Home Spray Refill for Dogs, 32-fl oz bottle
Vet's Best Indoor Flea & Tick Home Spray Refill for Dogs, 32-fl oz bottle
Vet's Best Indoor Flea & Tick Home Spray Refill for Dogs, 32-fl oz bottle
Vet's Best Indoor Flea & Tick Home Spray Refill for Dogs, 32-fl oz bottle
Vet's Best Indoor Flea & Tick Home Spray Refill for Dogs, 32-fl oz bottle
Vet's Best Indoor Flea & Tick Home Spray Refill for Dogs, 32-fl oz bottle

Vet's Best Indoor Flea & Tick Home Spray Refill for Dogs, 32-fl oz bottle

Rated 4.1 out of 5 stars
1,590
$12.25Chewy Price
($0.39/fl oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Duration of Protection

3.9/5
Good

Ease of Use

4.1/5
Great

Effectiveness

4.1/5
Great

Safety

4.0/5
Great

Is this home flea & tick treatment right for my pet?

Lifestage

All Lifestages, Adult

Top Ingredients

Peppermint Oil 0.30%, Eugenol (Clove Extract) 0.70%, Sodium Lauryl Sulfate 2.70%, Inert Ingredients (Water and Sodium Benzoate 96.30%
5
PetArmor Home & Carpet Spray Fresh Scent for Pets, 16-fl oz bottle
PetArmor Home & Carpet Spray Fresh Scent for Pets, 16-fl oz bottle
PetArmor Home & Carpet Spray Fresh Scent for Pets, 16-fl oz bottle
PetArmor Home & Carpet Spray Fresh Scent for Pets, 16-fl oz bottle
PetArmor Home & Carpet Spray Fresh Scent for Pets, 16-fl oz bottle
PetArmor Home & Carpet Spray Fresh Scent for Pets, 16-fl oz bottle

PetArmor Home & Carpet Spray Fresh Scent for Pets, 16-fl oz bottle

Rated 4.5 out of 5 stars
166
$7.51Chewy Price
($0.47/fl oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Duration of Protection

4.3/5
Great

Ease of Use

4.4/5
Great

Effectiveness

4.4/5
Great

Safety

4.3/5
Great

Is this home flea & tick treatment right for my pet?

Lifestage

All Lifestages, Adult

Top Ingredients

3-phenoxybenzyl-(1RS, 3RS, 1RS, 3SR)-2, 2-dimethyl-3-(2-methylprop-1-enyl) cyclopropanecarboxylate

Health Feature

Pest Control, Anti-Parasitic
6
Advantage Household Spot & Crevice Spray, 24-fl oz spray
Advantage Household Spot & Crevice Spray, 24-fl oz spray
Advantage Household Spot & Crevice Spray, 24-fl oz spray
Advantage Household Spot & Crevice Spray, 24-fl oz spray
Advantage Household Spot & Crevice Spray, 24-fl oz spray
Advantage Household Spot & Crevice Spray, 24-fl oz spray
Advantage Household Spot & Crevice Spray, 24-fl oz spray

Advantage Household Spot & Crevice Spray, 24-fl oz spray

Rated 4.7 out of 5 stars
115
$20.98Chewy Price
($0.88/fl oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Duration of Protection

4.0/5
Great

Ease of Use

4.3/5
Great

Effectiveness

4.4/5
Great

Safety

4.3/5
Great

Is this home flea & tick treatment right for my pet?

Lifestage

All Lifestages, Adult

Top Ingredients

Active Ingredients: 0.40% Sumithrin, 1.00% mgk 264 Insecticide Synergist, 0.05% Imidacloprid
7
Hartz Nature's Shield Natural Flea & Tick Home Spray
Hartz Nature's Shield Natural Flea & Tick Home Spray
Hartz Nature's Shield Natural Flea & Tick Home Spray
Hartz Nature's Shield Natural Flea & Tick Home Spray
Hartz Nature's Shield Natural Flea & Tick Home Spray
Hartz Nature's Shield Natural Flea & Tick Home Spray
Hartz Nature's Shield Natural Flea & Tick Home Spray

Hartz Nature's Shield Natural Flea & Tick Home Spray

Rated 4.2 out of 5 stars
266
$9.98Chewy Price
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Duration of Protection

4.1/5
Great

Ease of Use

4.2/5
Great

Effectiveness

4.2/5
Great

Safety

4.2/5
Great

Is this home flea & tick treatment right for my pet?

Lifestage

All Lifestages, Adult

Top Ingredients

Lemongrass Oil, Cedarwood Oil, Sodium Lauryl Sulfate

Health Feature

Anti-Parasitic, Pest Control
8
Fleabusters RX for Fleas Plus Powder, 3-lb jar
Fleabusters RX for Fleas Plus Powder, 3-lb jar
Fleabusters RX for Fleas Plus Powder, 3-lb jar

Fleabusters RX for Fleas Plus Powder, 3-lb jar

Rated 4 out of 5 stars
177
$36.48Chewy Price
($12.16/lb)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Duration of Protection

4.2/5
Great

Ease of Use

4.3/5
Great

Effectiveness

4.4/5
Great

Safety

4.2/5
Great

Is this home flea & tick treatment right for my pet?

Lifestage

All Lifestages, Adult

Top Ingredient

Active Ingredients: Orthoboric Acid 64.00% Inert Ingredients: 36.00%

Health Feature

Anti-Parasitic
9
Adams Flea & Tick Carpet Powder, 16-oz bottle
Adams Flea & Tick Carpet Powder, 16-oz bottle
Adams Flea & Tick Carpet Powder, 16-oz bottle
Adams Flea & Tick Carpet Powder, 16-oz bottle
Adams Flea & Tick Carpet Powder, 16-oz bottle
Adams Flea & Tick Carpet Powder, 16-oz bottle
Adams Flea & Tick Carpet Powder, 16-oz bottle
Adams Flea & Tick Carpet Powder, 16-oz bottle

Adams Flea & Tick Carpet Powder, 16-oz bottle

Rated 4 out of 5 stars
199
$11.12Chewy Price
($0.70/oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Duration of Protection

3.8/5
Good

Ease of Use

4.2/5
Great

Effectiveness

4.4/5
Great

Safety

4.3/5
Great

Is this home flea & tick treatment right for my pet?

Lifestage

All Lifestages, Adult

Top Ingredients

LiN/Alool 2.500%, Piperonyl Butoxide 0.500%, Pyrethrins 0.075%, Pyriproxyfen 0.020%, OTHER INGREDIENTS: 96.905%

Health Feature

Pest Control
10
TropiClean Natural Flea & Tick Treatment Spray for Dogs, Citrus Scent, 16-fl oz bottle
TropiClean Natural Flea & Tick Treatment Spray for Dogs, Citrus Scent, 16-fl oz bottle
TropiClean Natural Flea & Tick Treatment Spray for Dogs, Citrus Scent, 16-fl oz bottle
TropiClean Natural Flea & Tick Treatment Spray for Dogs, Citrus Scent, 16-fl oz bottle
TropiClean Natural Flea & Tick Treatment Spray for Dogs, Citrus Scent, 16-fl oz bottle
TropiClean Natural Flea & Tick Treatment Spray for Dogs, Citrus Scent, 16-fl oz bottle
TropiClean Natural Flea & Tick Treatment Spray for Dogs, Citrus Scent, 16-fl oz bottle
TropiClean Natural Flea & Tick Treatment Spray for Dogs, Citrus Scent, 16-fl oz bottle

TropiClean Natural Flea & Tick Treatment Spray for Dogs, Citrus Scent, 16-fl oz bottle

Rated 4.2 out of 5 stars
220
$14.99Chewy Price
($0.94/fl oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Duration of Protection

4.1/5
Great

Ease of Use

4.2/5
Great

Effectiveness

4.2/5
Great

Safety

4.0/5
Great

Is this home flea & tick treatment right for my pet?

Breed Size

Extra Small Breeds, Small Breeds, Medium Breeds, Large Breeds...

Lifestage

All Lifestages, Adult

Top Ingredients

Clove Oil, Lemongrass Oil, Cedarwood Oil, Cinnamon Oil, Sesame Seed Oil

Health Feature

Pest Control, Anti-Parasitic