10 Best Immune System & Allergy Supplements for Dogs 2024: According to Reviews | Chewy

The 10 Best Immune System & Allergy Supplements for Dogs

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How we created this immune system & allergy supplement list

We leveraged input from our veterinarians and artificial intelligence to identify key considerations to help you find the best immune system & allergy supplements for dog.
We scanned thousands of customer reviews and ratings and scored each product based on its performance against each of the key considerations. We then considered how popular a product is with Chewy customers and combined that with its key consideration scores to create the list of the best immune system & allergy supplements for dogs.

Key immune system & allergy supplement considerations

Dosage and Administration

Effectiveness

Ingredients

Safety

1
PetHonesty Allergy Support Salmon Flavor Allergy, Immune & Itchy Skin Relief Supplement for Dogs, 90 count
PetHonesty Allergy Support Salmon Flavor Allergy, Immune & Itchy Skin Relief Supplement for Dogs, 90 count
PetHonesty Allergy Support Salmon Flavor Allergy, Immune & Itchy Skin Relief Supplement for Dogs, 90 count
PetHonesty Allergy Support Salmon Flavor Allergy, Immune & Itchy Skin Relief Supplement for Dogs, 90 count
PetHonesty Allergy Support Salmon Flavor Allergy, Immune & Itchy Skin Relief Supplement for Dogs, 90 count
PetHonesty Allergy Support Salmon Flavor Allergy, Immune & Itchy Skin Relief Supplement for Dogs, 90 count
PetHonesty Allergy Support Salmon Flavor Allergy, Immune & Itchy Skin Relief Supplement for Dogs, 90 count
PetHonesty Allergy Support Salmon Flavor Allergy, Immune & Itchy Skin Relief Supplement for Dogs, 90 count
PetHonesty Allergy Support Salmon Flavor Allergy, Immune & Itchy Skin Relief Supplement for Dogs, 90 count

PetHonesty Allergy Support Salmon Flavor Allergy, Immune & Itchy Skin Relief Supplement for Dogs, 90 count

Rated 4.3 out of 5 stars
4,650
$29.99Chewy Price
Promo, Save 50% off First Autoship

Our ratings

Dosage and Administration
4.5/5
Great
Effectiveness
4.5/5
Great
Ingredients
4.5/5
Great
Safety
4.5/5
Great

Is this immune system & allergy supplement right for my pet?

Breed Size
All Breeds
Lifestage
All Lifestages, Adult
Top Ingredients
Active Ingredients: Colostrum, Organic Turmeric Root, Wild Alaskan Salmon Oil, Vitamin C, Organic Mushroom Blend
Special Diet
No Corn No Wheat No Soy, Non-GMO
2
Zesty Paws Allergy & Immune Bites Lamb Flavored Soft Chews Allergies, Immune, & Gut Support Supplement for Dogs, 90 count
Zesty Paws Allergy & Immune Bites Lamb Flavored Soft Chews Allergies, Immune, & Gut Support Supplement for Dogs, 90 count
Zesty Paws Allergy & Immune Bites Lamb Flavored Soft Chews Allergies, Immune, & Gut Support Supplement for Dogs, 90 count
Zesty Paws Allergy & Immune Bites Lamb Flavored Soft Chews Allergies, Immune, & Gut Support Supplement for Dogs, 90 count
Zesty Paws Allergy & Immune Bites Lamb Flavored Soft Chews Allergies, Immune, & Gut Support Supplement for Dogs, 90 count
Zesty Paws Allergy & Immune Bites Lamb Flavored Soft Chews Allergies, Immune, & Gut Support Supplement for Dogs, 90 count
Zesty Paws Allergy & Immune Bites Lamb Flavored Soft Chews Allergies, Immune, & Gut Support Supplement for Dogs, 90 count
Zesty Paws Allergy & Immune Bites Lamb Flavored Soft Chews Allergies, Immune, & Gut Support Supplement for Dogs, 90 count
Zesty Paws Allergy & Immune Bites Lamb Flavored Soft Chews Allergies, Immune, & Gut Support Supplement for Dogs, 90 count

Zesty Paws Allergy & Immune Bites Lamb Flavored Soft Chews Allergies, Immune, & Gut Support Supplement for Dogs, 90 count

Rated 4.5 out of 5 stars
3,435
$32.97Chewy Price
Promo, New Customers Only: Spend $49+, Get $20 eGift Card + Free Shipping with code: WELCOME

Our ratings

Dosage and Administration
4.1/5
Great
Effectiveness
4.2/5
Great
Ingredients
4.2/5
Great
Safety
4.2/5
Great

Is this immune system & allergy supplement right for my pet?

Breed Size
All Breeds
Lifestage
All Lifestages, Adult
Top Ingredients
Active Ingredients: Colostrum (Bovine), Dried Fermentate (Made Using Saccharomyces cerevisiae) (EpiCor® Pets), Astragalus Root, 6-Strain Gut Health Blend (Bacillus subtilis, Lactobacillus acidophilus
Food Flavor
Lamb, Meat
3
Vibeful Allergy & Immune Support Peanut Butter Flavored Soft Chews Allergy & Immune Supplement for Dogs, 90 Count
Vibeful Allergy & Immune Support Peanut Butter Flavored Soft Chews Allergy & Immune Supplement for Dogs, 90 Count
Vibeful Allergy & Immune Support Peanut Butter Flavored Soft Chews Allergy & Immune Supplement for Dogs, 90 Count
Vibeful Allergy & Immune Support Peanut Butter Flavored Soft Chews Allergy & Immune Supplement for Dogs, 90 Count
Vibeful Allergy & Immune Support Peanut Butter Flavored Soft Chews Allergy & Immune Supplement for Dogs, 90 Count
Vibeful Allergy & Immune Support Peanut Butter Flavored Soft Chews Allergy & Immune Supplement for Dogs, 90 Count
Vibeful Allergy & Immune Support Peanut Butter Flavored Soft Chews Allergy & Immune Supplement for Dogs, 90 Count
Vibeful Allergy & Immune Support Peanut Butter Flavored Soft Chews Allergy & Immune Supplement for Dogs, 90 Count

Vibeful Allergy & Immune Support Peanut Butter Flavored Soft Chews Allergy & Immune Supplement for Dogs, 90 Count

Rated 4.2 out of 5 stars
311
$25.99Chewy Price
Promo, New Customers Only: Spend $49+, Get $20 eGift Card + Free Shipping with code: WELCOME

Our ratings

Dosage and Administration
4.3/5
Great
Effectiveness
4.3/5
Great
Ingredients
4.4/5
Great
Safety
4.3/5
Great

Is this immune system & allergy supplement right for my pet?

Breed Size
All Breeds
Lifestage
All Lifestages, Adult
Top Ingredients
Active Ingredients: Colostrum, Apple Cider Vinegar, Salmon Oil, Astragalus Root, Wellmune® Baker’s Yeast Beta 1
Food Flavor
Peanut Butter
4
Finn Allergy & Itch Beef Liver Flavored Soft Chew Allergy Supplement for Dogs, 90 count
Finn Allergy & Itch Beef Liver Flavored Soft Chew Allergy Supplement for Dogs, 90 count
Finn Allergy & Itch Beef Liver Flavored Soft Chew Allergy Supplement for Dogs, 90 count
Finn Allergy & Itch Beef Liver Flavored Soft Chew Allergy Supplement for Dogs, 90 count
Finn Allergy & Itch Beef Liver Flavored Soft Chew Allergy Supplement for Dogs, 90 count
Finn Allergy & Itch Beef Liver Flavored Soft Chew Allergy Supplement for Dogs, 90 count
Finn Allergy & Itch Beef Liver Flavored Soft Chew Allergy Supplement for Dogs, 90 count
Finn Allergy & Itch Beef Liver Flavored Soft Chew Allergy Supplement for Dogs, 90 count
Finn Allergy & Itch Beef Liver Flavored Soft Chew Allergy Supplement for Dogs, 90 count

Finn Allergy & Itch Beef Liver Flavored Soft Chew Allergy Supplement for Dogs, 90 count

Rated 4.2 out of 5 stars
860
$31.79Chewy Price
Promo, New Customers Only: Spend $49+, Get $20 eGift Card + Free Shipping with code: WELCOME

Our ratings

Dosage and Administration
4.4/5
Great
Effectiveness
4.5/5
Great
Ingredients
4.5/5
Great
Safety
4.5/5
Great

Is this immune system & allergy supplement right for my pet?

Breed Size
All Breeds
Lifestage
All Lifestages, Adult
Top Ingredients
Colostrum (Bovine): 150mg, Wild Alaskan Salmon Oil: 100mg, Fructooligosaccharides (FOS): 100 mg, Quercetin: 50mg, Bee Propolis: 10mg
Special Diet
Grain-Free, No Corn No Wheat No Soy, Chicken-Free, Natural
5
Pupford Gut Health & Immunity Peanut Butter & Jelly Flavored Soft Chew Digestive Support Supplement for Puppies, 60 count
Pupford Gut Health & Immunity Peanut Butter & Jelly Flavored Soft Chew Digestive Support Supplement for Puppies, 60 count
Pupford Gut Health & Immunity Peanut Butter & Jelly Flavored Soft Chew Digestive Support Supplement for Puppies, 60 count
Pupford Gut Health & Immunity Peanut Butter & Jelly Flavored Soft Chew Digestive Support Supplement for Puppies, 60 count
Pupford Gut Health & Immunity Peanut Butter & Jelly Flavored Soft Chew Digestive Support Supplement for Puppies, 60 count
Pupford Gut Health & Immunity Peanut Butter & Jelly Flavored Soft Chew Digestive Support Supplement for Puppies, 60 count

Pupford Gut Health & Immunity Peanut Butter & Jelly Flavored Soft Chew Digestive Support Supplement for Puppies, 60 count

Rated 4.8 out of 5 stars
66
$21.99Chewy Price
Promo, New Customers Only: Spend $49+, Get $20 eGift Card + Free Shipping with code: WELCOME

Our ratings

Dosage and Administration
4.8/5
Excellent
Effectiveness
4.9/5
Excellent
Ingredients
4.8/5
Excellent
Safety
4.8/5
Excellent

Is this immune system & allergy supplement right for my pet?

Breed Size
All Breeds
Lifestage
Puppy
Top Ingredients
Pumpkin Powder, Chicory Root, Yea-Sacc OA, Tynagen, 7-strain Immunity Blend
Special Diet
Natural, No Corn No Wheat No Soy, Low Fat, Limited Ingredient Diet...
6
StrellaLab Dog Probiotics Enzymes Prebiotics Fiber Digestive Supplement, 120 count
StrellaLab Dog Probiotics Enzymes Prebiotics Fiber Digestive Supplement, 120 count
StrellaLab Dog Probiotics Enzymes Prebiotics Fiber Digestive Supplement, 120 count
StrellaLab Dog Probiotics Enzymes Prebiotics Fiber Digestive Supplement, 120 count
StrellaLab Dog Probiotics Enzymes Prebiotics Fiber Digestive Supplement, 120 count
StrellaLab Dog Probiotics Enzymes Prebiotics Fiber Digestive Supplement, 120 count
StrellaLab Dog Probiotics Enzymes Prebiotics Fiber Digestive Supplement, 120 count

StrellaLab Dog Probiotics Enzymes Prebiotics Fiber Digestive Supplement, 120 count

Rated 4.6 out of 5 stars
107
$23.83Chewy Price
Promo, New Customers Only: Spend $49+, Get $20 eGift Card + Free Shipping with code: WELCOME

Our ratings

Dosage and Administration
4.7/5
Excellent
Effectiveness
4.6/5
Excellent
Ingredients
4.7/5
Excellent
Safety
4.5/5
Great

Is this immune system & allergy supplement right for my pet?

Breed Size
All Breeds
Lifestage
All Lifestages, Adult
Top Ingredients
Brewers Dried Yeast, Dried Potato Product, Glycerin, Flaxseed, Lecithin
Special Diet
Rawhide-Free, No Corn No Wheat No Soy
7
Pet Parents Allergy SoftSupps Immune & Allergy Relief Dog Supplement, 90 count
Pet Parents Allergy SoftSupps Immune & Allergy Relief Dog Supplement, 90 count
Pet Parents Allergy SoftSupps Immune & Allergy Relief Dog Supplement, 90 count
Pet Parents Allergy SoftSupps Immune & Allergy Relief Dog Supplement, 90 count
Pet Parents Allergy SoftSupps Immune & Allergy Relief Dog Supplement, 90 count
Pet Parents Allergy SoftSupps Immune & Allergy Relief Dog Supplement, 90 count
Pet Parents Allergy SoftSupps Immune & Allergy Relief Dog Supplement, 90 count
Pet Parents Allergy SoftSupps Immune & Allergy Relief Dog Supplement, 90 count
Pet Parents Allergy SoftSupps Immune & Allergy Relief Dog Supplement, 90 count

Pet Parents Allergy SoftSupps Immune & Allergy Relief Dog Supplement, 90 count

Rated 4.5 out of 5 stars
103
$29.99Chewy Price
Promo, New Customers Only: Spend $49+, Get $20 eGift Card + Free Shipping with code: WELCOME

Our ratings

Dosage and Administration
4.7/5
Excellent
Effectiveness
4.7/5
Excellent
Ingredients
4.6/5
Excellent
Safety
4.7/5
Excellent

Is this immune system & allergy supplement right for my pet?

Breed Size
All Breeds
Lifestage
All Lifestages, Adult
Top Ingredients
Colostrum (250mg), Biomos(200mg), Apple Cider Vinegar (80mg), Wild Alaskan Salmon Oil (80mg), Organic Licorice Root (50mg)
Special Diet
No Corn No Wheat No Soy, Grain-Free, Chicken-Free, Soy Free
8
Native Pet Allergy & Immune Chews Allergy & Itch Relief Supplement for Dogs, 60 count
Native Pet Allergy & Immune Chews Allergy & Itch Relief Supplement for Dogs, 60 count
Native Pet Allergy & Immune Chews Allergy & Itch Relief Supplement for Dogs, 60 count
Native Pet Allergy & Immune Chews Allergy & Itch Relief Supplement for Dogs, 60 count
Native Pet Allergy & Immune Chews Allergy & Itch Relief Supplement for Dogs, 60 count
Native Pet Allergy & Immune Chews Allergy & Itch Relief Supplement for Dogs, 60 count
Native Pet Allergy & Immune Chews Allergy & Itch Relief Supplement for Dogs, 60 count

Native Pet Allergy & Immune Chews Allergy & Itch Relief Supplement for Dogs, 60 count

Rated 4.2 out of 5 stars
226
$24.99Chewy Price
Promo, New Customers Only: Spend $49+, Get $20 eGift Card + Free Shipping with code: WELCOME

Our ratings

Dosage and Administration
4.1/5
Great
Effectiveness
4.2/5
Great
Ingredients
4.2/5
Great
Safety
4.1/5
Great

Is this immune system & allergy supplement right for my pet?

Breed Size
All Breeds
Top Ingredients
Active Ingredients: Colustrum, Spirulina, Colostrum, Dried Yeast Fermentate, Algae Oil
Special Diet
Gluten Free, Natural, Limited Ingredient Diet, Grain-Free
Food Flavor
Chicken
9
PetHonesty Allergy Skin Health Salmon Flavored Allergy & Itch Relief, Omega-3 Supplement for Dogs, 90 count
PetHonesty Allergy Skin Health Salmon Flavored Allergy & Itch Relief, Omega-3 Supplement for Dogs, 90 count
PetHonesty Allergy Skin Health Salmon Flavored Allergy & Itch Relief, Omega-3 Supplement for Dogs, 90 count
PetHonesty Allergy Skin Health Salmon Flavored Allergy & Itch Relief, Omega-3 Supplement for Dogs, 90 count
PetHonesty Allergy Skin Health Salmon Flavored Allergy & Itch Relief, Omega-3 Supplement for Dogs, 90 count
PetHonesty Allergy Skin Health Salmon Flavored Allergy & Itch Relief, Omega-3 Supplement for Dogs, 90 count
PetHonesty Allergy Skin Health Salmon Flavored Allergy & Itch Relief, Omega-3 Supplement for Dogs, 90 count
PetHonesty Allergy Skin Health Salmon Flavored Allergy & Itch Relief, Omega-3 Supplement for Dogs, 90 count
PetHonesty Allergy Skin Health Salmon Flavored Allergy & Itch Relief, Omega-3 Supplement for Dogs, 90 count

PetHonesty Allergy Skin Health Salmon Flavored Allergy & Itch Relief, Omega-3 Supplement for Dogs, 90 count

Rated 4.4 out of 5 stars
1,089
$30.99Chewy Price
Promo, Save 50% off First Autoship

Our ratings

Dosage and Administration
4.5/5
Great
Effectiveness
4.6/5
Excellent
Ingredients
4.5/5
Great
Safety
4.5/5
Great

Is this immune system & allergy supplement right for my pet?

Breed Size
All Breeds
Lifestage
All Lifestages, Adult
Top Ingredients
Active Ingredients: Kelp, Krill, Omega-3 Fatty Acids (From Fish Oil & Flaxseed), Algae, Probiotics Blend (Bifidobacterium animalis
Special Diet
Non-GMO
10
PointPet Allergy Plus Calming Smoked Salmon Flavored Seasonal Allergy Support Soft Chew Dog Supplement, 120 Count
PointPet Allergy Plus Calming Smoked Salmon Flavored Seasonal Allergy Support Soft Chew Dog Supplement, 120 Count
PointPet Allergy Plus Calming Smoked Salmon Flavored Seasonal Allergy Support Soft Chew Dog Supplement, 120 Count
PointPet Allergy Plus Calming Smoked Salmon Flavored Seasonal Allergy Support Soft Chew Dog Supplement, 120 Count
PointPet Allergy Plus Calming Smoked Salmon Flavored Seasonal Allergy Support Soft Chew Dog Supplement, 120 Count
PointPet Allergy Plus Calming Smoked Salmon Flavored Seasonal Allergy Support Soft Chew Dog Supplement, 120 Count
PointPet Allergy Plus Calming Smoked Salmon Flavored Seasonal Allergy Support Soft Chew Dog Supplement, 120 Count
PointPet Allergy Plus Calming Smoked Salmon Flavored Seasonal Allergy Support Soft Chew Dog Supplement, 120 Count

PointPet Allergy Plus Calming Smoked Salmon Flavored Seasonal Allergy Support Soft Chew Dog Supplement, 120 Count

Rated 4.4 out of 5 stars
103
$37.95Chewy Price
Promo, New Customers Only: Spend $49+, Get $20 eGift Card + Free Shipping with code: WELCOME

Our ratings

Dosage and Administration
4.2/5
Great
Effectiveness
4.3/5
Great
Ingredients
4.2/5
Great
Safety
4.3/5
Great

Is this immune system & allergy supplement right for my pet?

Breed Size
All Breeds
Lifestage
All Lifestages, Adult
Top Ingredients
Colostrum, Bromelain, Chamomile, Quercetin Dihydrate, Ascorbic Acid (Vitamin C)
Special Diet
No Corn No Wheat No Soy, Non-GMO, Human-Grade