9 Best Powder Anxiety Supplements for Dogs 2025: According to Reviews | Chewy

The 9 Best Powder Anxiety Supplements for Dogs

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How we created this powder anxiety supplement list

We leveraged input from our veterinarians and artificial intelligence to identify key considerations to help you find the best powder anxiety supplements for dog.
We scanned thousands of customer reviews and ratings and scored each product based on its performance against each of the key considerations. We then considered how popular a product is with Chewy customers and combined that with its key consideration scores to create the list of the best powder anxiety supplements for dogs.

Key powder anxiety supplement considerations

Dosage

Effectiveness

Ingredients

Side Effects

1
Purina Pro Plan Veterinary Diets Calming Care Liver Flavored Powder Calming Supplement for Dogs, 30 count
Purina Pro Plan Veterinary Diets Calming Care Liver Flavored Powder Calming Supplement for Dogs, 30 count
Purina Pro Plan Veterinary Diets Calming Care Liver Flavored Powder Calming Supplement for Dogs, 30 count
Purina Pro Plan Veterinary Diets Calming Care Liver Flavored Powder Calming Supplement for Dogs, 30 count
Purina Pro Plan Veterinary Diets Calming Care Liver Flavored Powder Calming Supplement for Dogs, 30 count
Purina Pro Plan Veterinary Diets Calming Care Liver Flavored Powder Calming Supplement for Dogs, 30 count
Purina Pro Plan Veterinary Diets Calming Care Liver Flavored Powder Calming Supplement for Dogs, 30 count
Purina Pro Plan Veterinary Diets Calming Care Liver Flavored Powder Calming Supplement for Dogs, 30 count

Purina Pro Plan Veterinary Diets Calming Care Liver Flavored Powder Calming Supplement for Dogs, 30 count

Rated 4.3 out of 5 stars
1,479
$33.99Chewy Price
($1.14/ea)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Dosage

4.2/5
Great

Effectiveness

4.3/5
Great

Ingredients

4.3/5
Great

Side Effects

4.2/5
Great

Is this powder anxiety supplement right for my pet?

Breed Size

All Breeds

Lifestage

Adult, All Lifestages

Top Ingredients

Active Ingredients: Bifidobacterium longum BL999 1x109 CFU., Inactive Ingredients: Liver flavor, Maltodextrin. B-2519

Food Flavor

Liver, Meat
2
Dr. Bill's Pet Nutrition Canine Cognitive Support Brain & Nervous System Senior Dog Supplement Powder, 180-gm pouch
Dr. Bill's Pet Nutrition Canine Cognitive Support Brain & Nervous System Senior Dog Supplement Powder, 180-gm pouch
Dr. Bill's Pet Nutrition Canine Cognitive Support Brain & Nervous System Senior Dog Supplement Powder, 180-gm pouch
Dr. Bill's Pet Nutrition Canine Cognitive Support Brain & Nervous System Senior Dog Supplement Powder, 180-gm pouch
Dr. Bill's Pet Nutrition Canine Cognitive Support Brain & Nervous System Senior Dog Supplement Powder, 180-gm pouch
Dr. Bill's Pet Nutrition Canine Cognitive Support Brain & Nervous System Senior Dog Supplement Powder, 180-gm pouch
Dr. Bill's Pet Nutrition Canine Cognitive Support Brain & Nervous System Senior Dog Supplement Powder, 180-gm pouch
Dr. Bill's Pet Nutrition Canine Cognitive Support Brain & Nervous System Senior Dog Supplement Powder, 180-gm pouch
Dr. Bill's Pet Nutrition Canine Cognitive Support Brain & Nervous System Senior Dog Supplement Powder, 180-gm pouch

Dr. Bill's Pet Nutrition Canine Cognitive Support Brain & Nervous System Senior Dog Supplement Powder, 180-gm pouch

Rated 4.5 out of 5 stars
42
$44.99Chewy Price
($0.25/g)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Dosage

4.4/5
Great

Effectiveness

4.6/5
Excellent

Ingredients

4.4/5
Great

Side Effects

4.4/5
Great

Is this powder anxiety supplement right for my pet?

Breed Size

All Breeds

Lifestage

Senior

Top Ingredients

Active Ingredients: Phosphatidylcholine, Phosphatidylinositol, Ginkgo biloba, Phosphatidylserine, L-Carnosine

Special Diet

Grain-Free, Human-Grade
3
Fera Pets Calm Goat Milk Topper for Dogs & Cats, 60 count
Fera Pets Calm Goat Milk Topper for Dogs & Cats, 60 count
Fera Pets Calm Goat Milk Topper for Dogs & Cats, 60 count

Fera Pets Calm Goat Milk Topper for Dogs & Cats, 60 count

Rated 4 out of 5 stars
24
$29.95Chewy Price
($0.50/ea)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Dosage

4.4/5
Great

Effectiveness

4.3/5
Great

Ingredients

4.5/5
Great

Side Effects

4.0/5
Great

Is this powder anxiety supplement right for my pet?

Breed Size

All Breeds

Lifestage

Adult, All Lifestages

Top Ingredient

Inactive Ingredients: Full Cream Goat's Milk

Food Flavor

Cheese
4
Austin and Kat Bailey's No More Wiggles Dog & Cat Supplement, 2.71-oz bag
Austin and Kat Bailey's No More Wiggles Dog & Cat Supplement, 2.71-oz bag
Austin and Kat Bailey's No More Wiggles Dog & Cat Supplement, 2.71-oz bag
Austin and Kat Bailey's No More Wiggles Dog & Cat Supplement, 2.71-oz bag
Austin and Kat Bailey's No More Wiggles Dog & Cat Supplement, 2.71-oz bag
Austin and Kat Bailey's No More Wiggles Dog & Cat Supplement, 2.71-oz bag
Austin and Kat Bailey's No More Wiggles Dog & Cat Supplement, 2.71-oz bag
Austin and Kat Bailey's No More Wiggles Dog & Cat Supplement, 2.71-oz bag

Austin and Kat Bailey's No More Wiggles Dog & Cat Supplement, 2.71-oz bag

Rated 4 out of 5 stars
8
$29.95Chewy Price
($11.06/oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Dosage

4.3/5
Great

Effectiveness

4.7/5
Excellent

Ingredients

4.7/5
Excellent

Side Effects

4.2/5
Great

Is this powder anxiety supplement right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Ashwagandha Root Extract 450mg, Icelandic Kelp 325mg, Spirulina Blue-green Algae 150mg, Valerian Root Extract 150mg, King Trumpet Mushroom 150mg

Special Diet

Gluten Free, Grain-Free, Limited Ingredient Diet, Natural...
5
Stashios Soothing Sauce Chicken Flavor Calming Powder Supplement for Dogs & Cats, 3-oz bag
Stashios Soothing Sauce Chicken Flavor Calming Powder Supplement for Dogs & Cats, 3-oz bag
Stashios Soothing Sauce Chicken Flavor Calming Powder Supplement for Dogs & Cats, 3-oz bag

Stashios Soothing Sauce Chicken Flavor Calming Powder Supplement for Dogs & Cats, 3-oz bag

Rated 4.1 out of 5 stars
11
$16.99Chewy Price
($5.67/oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Dosage

4.1/5
Great

Effectiveness

4.4/5
Great

Ingredients

4.2/5
Great

Side Effects

4.4/5
Great

Is this powder anxiety supplement right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Chicken Bone Broth, Ashwagandha Extract Powder, Magnolia Bark Extract Powder, Lavender Extract Powder

Special Diet

High-Protein, Gluten Free, Limited Ingredient Diet, Grain-Free
6
The Petz Kitchen Holistic Super Food Broth Cognitive Support Beef Flavor Concentrate Powder Dog & Cat Supplement, 4.5-oz bag
The Petz Kitchen Holistic Super Food Broth Cognitive Support Beef Flavor Concentrate Powder Dog & Cat Supplement, 4.5-oz bag
The Petz Kitchen Holistic Super Food Broth Cognitive Support Beef Flavor Concentrate Powder Dog & Cat Supplement, 4.5-oz bag
The Petz Kitchen Holistic Super Food Broth Cognitive Support Beef Flavor Concentrate Powder Dog & Cat Supplement, 4.5-oz bag
The Petz Kitchen Holistic Super Food Broth Cognitive Support Beef Flavor Concentrate Powder Dog & Cat Supplement, 4.5-oz bag
The Petz Kitchen Holistic Super Food Broth Cognitive Support Beef Flavor Concentrate Powder Dog & Cat Supplement, 4.5-oz bag
The Petz Kitchen Holistic Super Food Broth Cognitive Support Beef Flavor Concentrate Powder Dog & Cat Supplement, 4.5-oz bag

The Petz Kitchen Holistic Super Food Broth Cognitive Support Beef Flavor Concentrate Powder Dog & Cat Supplement, 4.5-oz bag

Rated 4.8 out of 5 stars
5
$24.95Chewy Price
($5.55/oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Dosage

4.6/5
Excellent

Effectiveness

4.7/5
Excellent

Ingredients

4.7/5
Excellent

Side Effects

4.6/5
Excellent

Is this powder anxiety supplement right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Beef Liver, Chia Seeds, Kelp, Sweet Potato, Yellow Maca

Special Diet

Organic, No Corn No Wheat No Soy, Non-GMO
7
Super Snouts Lion's Roar Powder Brain & Nervous System Supplement for Dogs & Cats, 2.64-oz jar
Super Snouts Lion's Roar Powder Brain & Nervous System Supplement for Dogs & Cats, 2.64-oz jar
Super Snouts Lion's Roar Powder Brain & Nervous System Supplement for Dogs & Cats, 2.64-oz jar
Super Snouts Lion's Roar Powder Brain & Nervous System Supplement for Dogs & Cats, 2.64-oz jar
Super Snouts Lion's Roar Powder Brain & Nervous System Supplement for Dogs & Cats, 2.64-oz jar
Super Snouts Lion's Roar Powder Brain & Nervous System Supplement for Dogs & Cats, 2.64-oz jar
Super Snouts Lion's Roar Powder Brain & Nervous System Supplement for Dogs & Cats, 2.64-oz jar
Super Snouts Lion's Roar Powder Brain & Nervous System Supplement for Dogs & Cats, 2.64-oz jar
Super Snouts Lion's Roar Powder Brain & Nervous System Supplement for Dogs & Cats, 2.64-oz jar

Super Snouts Lion's Roar Powder Brain & Nervous System Supplement for Dogs & Cats, 2.64-oz jar

Rated 4.3 out of 5 stars
10
$26.99Chewy Price
($10.23/oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Dosage

4.6/5
Excellent

Effectiveness

4.6/5
Excellent

Ingredients

4.6/5
Excellent

Side Effects

4.3/5
Great

Is this powder anxiety supplement right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Active Ingredients Per Scoop (1g): Organic Lion’s Mane…1000mg, Inactive Ingredients: Fermented Organic Brown Rice

Special Diet

Limited Ingredient Diet, Natural
8
The Petz Kitchen Holistic Super Food Broth Anxiety Support Beef Flavor Concentrate Powder Dog & Cat Supplement, 4.5-oz bag
The Petz Kitchen Holistic Super Food Broth Anxiety Support Beef Flavor Concentrate Powder Dog & Cat Supplement, 4.5-oz bag
The Petz Kitchen Holistic Super Food Broth Anxiety Support Beef Flavor Concentrate Powder Dog & Cat Supplement, 4.5-oz bag
The Petz Kitchen Holistic Super Food Broth Anxiety Support Beef Flavor Concentrate Powder Dog & Cat Supplement, 4.5-oz bag
The Petz Kitchen Holistic Super Food Broth Anxiety Support Beef Flavor Concentrate Powder Dog & Cat Supplement, 4.5-oz bag
The Petz Kitchen Holistic Super Food Broth Anxiety Support Beef Flavor Concentrate Powder Dog & Cat Supplement, 4.5-oz bag
The Petz Kitchen Holistic Super Food Broth Anxiety Support Beef Flavor Concentrate Powder Dog & Cat Supplement, 4.5-oz bag

The Petz Kitchen Holistic Super Food Broth Anxiety Support Beef Flavor Concentrate Powder Dog & Cat Supplement, 4.5-oz bag

Rated 3 out of 5 stars
2
$24.95Chewy Price
($5.55/oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Dosage

4.5/5
Great

Effectiveness

4.5/5
Great

Ingredients

4.5/5
Great

Side Effects

4.5/5
Great

Is this powder anxiety supplement right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Beef Liver, Chia Seeds, Kelp, Sweet Potato, Passion Flower

Special Diet

Organic, No Corn No Wheat No Soy, Non-GMO
9
Natura Petz Organics TRAVEL WELL MEAL TOPPER* Stress, Relaxation & Calming Support* Dog Supplement, 4-oz jar
Natura Petz Organics TRAVEL WELL MEAL TOPPER* Stress, Relaxation & Calming Support* Dog Supplement, 4-oz jar
Natura Petz Organics TRAVEL WELL MEAL TOPPER* Stress, Relaxation & Calming Support* Dog Supplement, 4-oz jar
Natura Petz Organics TRAVEL WELL MEAL TOPPER* Stress, Relaxation & Calming Support* Dog Supplement, 4-oz jar
Natura Petz Organics TRAVEL WELL MEAL TOPPER* Stress, Relaxation & Calming Support* Dog Supplement, 4-oz jar

Natura Petz Organics TRAVEL WELL MEAL TOPPER* Stress, Relaxation & Calming Support* Dog Supplement, 4-oz jar

Rated 5 out of 5 stars
1
$29.99Chewy Price
($7.50/oz)
Promo, New Customers Only: Spend $49+, Get $20 eGift Card

Our ratings

Dosage

4.5/5
Great

Effectiveness

4.5/5
Great

Ingredients

4.5/5
Great

Side Effects

4.5/5
Great

Is this powder anxiety supplement right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Passion Flower, Mint, Turkey Flavoring

Special Diet

Organic, No Corn No Wheat No Soy, Non-GMO