Heartgard Plus Chew for Dogs, 51-100 lbs, (Brown Box)

By Heartgard
Rated 4.8828 out of 5 stars
Prescription Item

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$69.49Chewy Price
$78.89Chewy Price
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$9.40 (12%)
$66.02Autoship Price
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Usually arrives in 3-5 days
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Medications ship separately. Delivery times may vary.

Frequently Bought Together

NexGard Chew for Dogs, 60.1-121 lbs, (Red Box), 6 Chews (6-mos. supply)
Rated 4.5831 out of 5 stars
$139.99Chewy Price
Total Price: $278.48

About This Item


For use in animals only. Heartgard Plus Chew for Dogs, 51-100 lbs. is a heartworm preventative that kills heartworms and also helps treat and control roundworms and hookworms. It comes in a delicious once-a-month, real-beef chew that dogs love and is safe for puppies 6 weeks and older. Head back to the dog park, reassured that your dog is protected from nasty parasites with this heartworm preventative that's trusted over 2 billion times! Your furry friend must have a current heartworm test result on file with your veterinarian in order to be prescribed heartworm medication. Please visit your veterinarian to have this test performed annually to protect your four-legged friend.

Proudly sourced directly from the manufacturer or their approved distributor. Guaranteed genuine and backed by the manufacturer.

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Play Video: Learn More About Heartgard From Our Team of Experts
Learn More About Heartgard From Our Team of Experts

About HEARTGARD Plus for Dogs

#1 with Dog and Vets*

When it comes to preventing the invisible threat of heartworm disease, pet parents and veterinarians can agree that HEARTGARD Plus (ivermectin/pyrantel) is the #1 choice.* Not only does it prevent heartworm disease, but it also treats and controls 3 species of hookworms and 2 species of roundworms all with the real-beef taste dogs love.*

Why Choose HEARTGARD Plus?

When it comes to preventing the invisible threat of heartworm disease, pet parents and veterinarians can agree that HEARTGARD Plus (ivermectin/pyrantel) is the #1 choice.* Not only does it prevent heartworm disease, but it also treats and controls 3 species of hookworms and 2 species of roundworms all with the real-beef taste dogs love.*

Heartworm Prevention

The invisible threat of heartworm disease can be caused by one bite from an infected mosquito.

Veterinarian #1 Choice*

With over 2 billion doses prescribed, HEARTGARD Plus is the #1 choice of vets for their patients and their own dogs.*

#1 Dog-Preferred Chew*

The real-beef chew makes monthly dosing easy and enjoyable.*

Monthly Protection

When given every 30 days, HEARTGARD Plus can help keep your dog protected year-round.

Hookworms and Roundworms

Also treats and controls 3 species of hookworms and 2 species of roundworms.

Safe for Puppies

Safe for puppies as young as 6 weeks old with no minimum weight requirement.

For Dogs of All Sizes

Comes in three sizes: Up to 25 lbs., 26-50 lbs. and 51-100 lbs.

Heartworm Disease is an Invisible Threat

A Year-Round Risk for All Dogs

1 million dogs are estimated to be heartworm positive in the USA with cases reported in all 50 states.* The American Heartworm Society (AHS) recommends protecting dogs year-round and testing for heartworm disease every 12 months.*

1.  A mosquito ingests heartworm microfilariae after feeding on an infected animal.

2. Microfilariae become larvae and the mosquito can infect the next dog.

3. Larvae left on the skin develop in dogs.

4. Heartworm larvae migrate from the skin into the bloodstream of their new host, maturing as they go

5. Juvenile and adult heartworms primarily live in the pulmonary blood vessels of an infected dog.

6. Within 6 months of infection, adult heartworms are present in the pulmonary arteries.

7. When a mosquito bites an infected dog, the cycle can begin again.

Product Guide

HEARTGARD Plus is available in a variety of sizes by dog weight. Choose the option that best fits your dog.


Up to 25 lbs

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26 - 50 lbs

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51 - 100 lbs

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Just one bite from an infected mosquito could put your dog at risk for heartworm disease, but HEARTGARD Plus offers the protection your dog needs. This heartworm preventive is made with real beef and has a savory taste, making it the #1 dog-preferred chew. HEARTGARD Plus makes protecting your dog year-round easy and enjoyable month after month.*



  1. Data on file at Boehringer Ingelheim.
  2. HEARTGARD® Plus (ivermectin/pyrantel) Chewables [Freedom of Information Summary; NADA 140-971]. Duluth, GA: Boehringer Ingelheim Animal Health USA Inc.
  3. Heartworm prevalent in South, expanding in other hot spots. American Veterinary Medical Association. https://www.avma.org/javma-news/2020-08-01/heartwormprevalent-south-expanding-other-hot-spots. Accessed December 23, 2021.
  4. Heartworm Parasite Prevalence Maps. Companion Animal Parasite Council. https://capcvet.org/maps/#/2020/all/heartworm-canine/dog/united-states. Accessed November 18, 2021.
  5. Heartworm Guidelines. American Heartworm Society. https://www.heartwormsociety.org/veterinary-resources/ american-heartworm-society-guidelines. Accessed December 23, 2021.

ReviewsWrite a Review

Rated 4.8828 out of 5 stars
1450 Ratings
Would recommend to a friend

1432 Customer Reviews

Always consult a veterinarian about your pet’s health needs. Customer reviews should not be used as medical advice.
Rated 5 out of 5 stars
By John on Sep 12, 2023


I received my Chewy order yesterday and did not realise it came with a bonus product, new bed for Katniss!! She really likes the new boxbed. Our dog Moonshine is jealous because he cannot fit in it also but decided a nap sounded like a good idea. Thanks Chewy, keep up the good work.

Rated 5 out of 5 stars
By Mark on Sep 15, 2023

Super Easy!

Your company is great! I don’t say that lightly as I usually am not impressed with most companies customer services. Every time I have dealt with you has been super easy and professional including any mistakes made by me or you! Keep up the good work!

Rated 1 out of 5 stars
By Cacey on Sep 18, 2023

Chewy, not the product

My issue is with Chewy, not the actual product. I cancelled this auto ship previously and it still showed up. I was told it was forwarded to a different department and still haven’t heard a response or resolution to this matter.

Rated 5 out of 5 stars
By Jennifer on Sep 12, 2023

Great product

I like this product for my 70 lb lab mix because I know I don't have to worry about heartworms and also intestinal worms. My boy can romp and play in the grass and woods as long as I'm close by. Still worry about snakes and spiders of course!

Rated 3 out of 5 stars
By Robindt on Sep 4, 2023

Good product but overpriced

I called twice to verify if I ordered this through Chewy would it qualify for the $20 discount. I was assured it would be. But when it was charged to my account I ended up paying the full amount. I could of paid less from my Vets office. Very disappointed in Chewy!

Rated 5 out of 5 stars
By william on Aug 27, 2023

split order

While the products are fine it does bother me that they were supposed to be together with the other part of my order, but came two different days. Meaning I have to watch 2 days for the packages. Not the biggest deal in the wor;d, but you asked.

Rated 5 out of 5 stars
By Amy on Jul 30, 2023

Great product great price

My three dogs have been taking Heart Guard for years now and they love eating it. I have a lab who will eat anything I I give him, a puppy who doesn’t really care what it tastes like but loves the chewiness of it and an extremely picky Yorkie who doesn’t like anything and they all love it. Heart worm care without the drama of taking “medicine “. Thanks heartguard!

Rated 4 out of 5 stars
By Concern on Sep 5, 2023

Necessay but pricey

I appreciate the first discounted shipment but the pharmaceutical co.pa ies seem to have Carte blanche on pricing and it is pricing itself out of my budget. What can be done to control pricing? It is criminal.

Rated 5 out of 5 stars
By Gracie on Sep 16, 2023

Heartgard Order

I have been extremely pleased with Chewy's quick service and shipping. They make it easy to keep my dogs healthy. My vet does not offer Heartgard so I am thankful for Chewy.

Rated 5 out of 5 stars
By Karen on Sep 21, 2023

Great Prevention

Heartgard is perfect for Heart worm prevention. I have used it on all my pups and never had an issue with any of them! Highly recommend