10 Best Anti-Itch Treatments for Cats 2025: According to Reviews | Chewy

The 10 Best Anti-Itch Treatments for Cats

Jump to the list

How we created this anti-itch treatment list

We leveraged input from our veterinarians and artificial intelligence to identify key considerations to help you find the best anti-itch treatments for cat.
We scanned thousands of customer reviews and ratings and scored each product based on its performance against each of the key considerations. We then considered how popular a product is with Chewy customers and combined that with its key consideration scores to create the list of the best anti-itch treatments for cats.

Key anti-itch treatment considerations

Active Ingredients

Application Method

Effectiveness

Long-Term Results

1
Earthbath Oatmeal & Aloe Dog & Cat Shampoo, 16-fl oz bottle
Earthbath Oatmeal & Aloe Dog & Cat Shampoo, 16-fl oz bottle
Earthbath Oatmeal & Aloe Dog & Cat Shampoo, 16-fl oz bottle
Earthbath Oatmeal & Aloe Dog & Cat Shampoo, 16-fl oz bottle
Earthbath Oatmeal & Aloe Dog & Cat Shampoo, 16-fl oz bottle
Earthbath Oatmeal & Aloe Dog & Cat Shampoo, 16-fl oz bottle
Earthbath Oatmeal & Aloe Dog & Cat Shampoo, 16-fl oz bottle
Earthbath Oatmeal & Aloe Dog & Cat Shampoo, 16-fl oz bottle

Earthbath Oatmeal & Aloe Dog & Cat Shampoo, 16-fl oz bottle

Rated 4.7 out of 5 stars
1,077
$16.99Chewy Price
($1.07/fl oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Active Ingredients

4.5/5
Great

Application Method

4.6/5
Excellent

Effectiveness

4.6/5
Excellent

Long-Term Results

4.7/5
Excellent

Is this anti-itch treatment right for my pet?

Lifestage

All Lifestages, Adult

Top Ingredients

Purified water, colloidal oatmeal, renewable plant-derived & coconut-based cleansers, organic aloe vera, vitamins A

Health Feature

Itch & Redness Remedy
2
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Cat & Dog Shampoo, 16-fl oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Cat & Dog Shampoo, 16-fl oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Cat & Dog Shampoo, 16-fl oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Cat & Dog Shampoo, 16-fl oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Cat & Dog Shampoo, 16-fl oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Cat & Dog Shampoo, 16-fl oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Cat & Dog Shampoo, 16-fl oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Cat & Dog Shampoo, 16-fl oz bottle

Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Cat & Dog Shampoo, 16-fl oz bottle

Rated 4.7 out of 5 stars
463
$21.99Chewy Price
($1.38/fl oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Active Ingredients

4.7/5
Excellent

Application Method

4.6/5
Excellent

Effectiveness

4.6/5
Excellent

Long-Term Results

4.6/5
Excellent

Is this anti-itch treatment right for my pet?

Breed Size

Small Breeds, Medium Breeds, Large Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Chlorhexidine Gluconate, Ketoconazole, Water, Lauramine Oxide, Polyacrylate-1 Crosspolymer

Health Feature

Anti-Fungal / Anti-Bacterial, Itch & Redness Remedy
3
Veterinary Formula Clinical Care Antiseptic & Antifungal Medicated Spray, 8-fl oz spray
Veterinary Formula Clinical Care Antiseptic & Antifungal Medicated Spray, 8-fl oz spray
Veterinary Formula Clinical Care Antiseptic & Antifungal Medicated Spray, 8-fl oz spray
Veterinary Formula Clinical Care Antiseptic & Antifungal Medicated Spray, 8-fl oz spray
Veterinary Formula Clinical Care Antiseptic & Antifungal Medicated Spray, 8-fl oz spray
Veterinary Formula Clinical Care Antiseptic & Antifungal Medicated Spray, 8-fl oz spray
Veterinary Formula Clinical Care Antiseptic & Antifungal Medicated Spray, 8-fl oz spray

Veterinary Formula Clinical Care Antiseptic & Antifungal Medicated Spray, 8-fl oz spray

Rated 4.5 out of 5 stars
982
$9.12Chewy Price
($1.14/fl oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Active Ingredients

4.5/5
Great

Application Method

4.5/5
Great

Effectiveness

4.5/5
Great

Long-Term Results

4.4/5
Great

Is this anti-itch treatment right for my pet?

Breed Size

Small Breeds, Medium Breeds, Large Breeds, Extra Small Breeds...

Lifestage

All Lifestages, Adult

Top Ingredients

Purified Water, Glycerin USP, Keratin, Poly-sorbate -20, Fragrance

Health Feature

Itch & Redness Remedy, Skin & Coat Health
4
Pet MD Chlorhexidine Antiseptic Wipes for Dogs & Cats, 50 count
Pet MD Chlorhexidine Antiseptic Wipes for Dogs & Cats, 50 count
Pet MD Chlorhexidine Antiseptic Wipes for Dogs & Cats, 50 count
Pet MD Chlorhexidine Antiseptic Wipes for Dogs & Cats, 50 count
Pet MD Chlorhexidine Antiseptic Wipes for Dogs & Cats, 50 count
Pet MD Chlorhexidine Antiseptic Wipes for Dogs & Cats, 50 count

Pet MD Chlorhexidine Antiseptic Wipes for Dogs & Cats, 50 count

Rated 4.4 out of 5 stars
684
$14.99Chewy Price
($0.30/ea)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Active Ingredients

4.3/5
Great

Application Method

4.3/5
Great

Effectiveness

4.5/5
Great

Long-Term Results

4.3/5
Great

Is this anti-itch treatment right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Active Ingredients (per wipe): Chlorhexidine 2% and Ketoconazole 1% in an alcohol-based solution., Inactive Ingredients: Water, Propylene Glycol, Nonoxynol-9, Lactic Acid

Health Feature

Skin & Coat Health, First Aid, Anti-Fungal / Anti-Bacterial
5
Davis Chlorhexidine Dog & Cat Spray, 8-fl oz bottle
Davis Chlorhexidine Dog & Cat Spray, 8-fl oz bottle
Davis Chlorhexidine Dog & Cat Spray, 8-fl oz bottle
Davis Chlorhexidine Dog & Cat Spray, 8-fl oz bottle
Davis Chlorhexidine Dog & Cat Spray, 8-fl oz bottle
Davis Chlorhexidine Dog & Cat Spray, 8-fl oz bottle
Davis Chlorhexidine Dog & Cat Spray, 8-fl oz bottle

Davis Chlorhexidine Dog & Cat Spray, 8-fl oz bottle

Rated 4.6 out of 5 stars
291
$11.30Chewy Price
($1.42/fl oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Active Ingredients

4.5/5
Great

Application Method

4.6/5
Excellent

Effectiveness

4.5/5
Great

Long-Term Results

4.5/5
Great

Is this anti-itch treatment right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Chlorhexidine Gluconate, Phospholipid Complex, PCMX, SDA 40, Polyoxyethylene Sorbitan Monolaurate

Health Feature

Itch & Redness Remedy, Skin & Coat Health
6
Zymox Topical Spray with Hydrocortisone 1.0% for Dogs & Cats, 2-fl oz bottle
Zymox Topical Spray with Hydrocortisone 1.0% for Dogs & Cats, 2-fl oz bottle
Zymox Topical Spray with Hydrocortisone 1.0% for Dogs & Cats, 2-fl oz bottle
Zymox Topical Spray with Hydrocortisone 1.0% for Dogs & Cats, 2-fl oz bottle
Zymox Topical Spray with Hydrocortisone 1.0% for Dogs & Cats, 2-fl oz bottle
Zymox Topical Spray with Hydrocortisone 1.0% for Dogs & Cats, 2-fl oz bottle
Zymox Topical Spray with Hydrocortisone 1.0% for Dogs & Cats, 2-fl oz bottle

Zymox Topical Spray with Hydrocortisone 1.0% for Dogs & Cats, 2-fl oz bottle

Rated 4.5 out of 5 stars
423
$16.99Chewy Price
($8.50/fl oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Active Ingredients

4.3/5
Great

Application Method

4.2/5
Great

Effectiveness

4.3/5
Great

Long-Term Results

4.2/5
Great

Is this anti-itch treatment right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Active Ingredients: Hydrocortisone 1.0%., Inactive Ingredients: Aloe Vera, Benzoic Acid, Benzyl Alcohol, Dipropylene Glycol

Health Feature

Itch & Redness Remedy, Skin & Coat Health
7
TropiClean OxyMed Medicated Anti-Itch Dog Shampoo, 20-fl oz bottle
TropiClean OxyMed Medicated Anti-Itch Dog Shampoo, 20-fl oz bottle
TropiClean OxyMed Medicated Anti-Itch Dog Shampoo, 20-fl oz bottle
TropiClean OxyMed Medicated Anti-Itch Dog Shampoo, 20-fl oz bottle
TropiClean OxyMed Medicated Anti-Itch Dog Shampoo, 20-fl oz bottle
TropiClean OxyMed Medicated Anti-Itch Dog Shampoo, 20-fl oz bottle
TropiClean OxyMed Medicated Anti-Itch Dog Shampoo, 20-fl oz bottle
TropiClean OxyMed Medicated Anti-Itch Dog Shampoo, 20-fl oz bottle
TropiClean OxyMed Medicated Anti-Itch Dog Shampoo, 20-fl oz bottle

TropiClean OxyMed Medicated Anti-Itch Dog Shampoo, 20-fl oz bottle

Rated 4.6 out of 5 stars
252
$16.99Chewy Price
($0.85/fl oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Active Ingredients

4.3/5
Great

Application Method

4.2/5
Great

Effectiveness

4.3/5
Great

Long-Term Results

4.1/5
Great

Is this anti-itch treatment right for my pet?

Breed Size

Extra Small Breeds, Small Breeds, Medium Breeds, Large Breeds...

Lifestage

Adult, All Lifestages

Top Ingredients

Water, Mild Coconut Cleanser, Beta Hydroxy, Sodium Chloride, Colloidal Oatmeal

Health Feature

Itch & Redness Remedy, Sensitive Skin, Skin & Coat Health, Allergy Relief
8
Banixx Pet Care+ Wound Care & Anti-Itch Spray for Dogs, Cats & Small Pets, 8-fl oz bottle
Banixx Pet Care+ Wound Care & Anti-Itch Spray for Dogs, Cats & Small Pets, 8-fl oz bottle
Banixx Pet Care+ Wound Care & Anti-Itch Spray for Dogs, Cats & Small Pets, 8-fl oz bottle
Banixx Pet Care+ Wound Care & Anti-Itch Spray for Dogs, Cats & Small Pets, 8-fl oz bottle

Banixx Pet Care+ Wound Care & Anti-Itch Spray for Dogs, Cats & Small Pets, 8-fl oz bottle

Rated 4.2 out of 5 stars
713
$16.99Chewy Price
($2.13/fl oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Active Ingredients

4.2/5
Great

Application Method

4.0/5
Great

Effectiveness

4.2/5
Great

Long-Term Results

4.2/5
Great

Is this anti-itch treatment right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredient

Sabilized Hydronium (H9 O4) & Purified Water

Health Feature

First Aid, Anti-Fungal / Anti-Bacterial
9
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Dog & Cat Skin Spray, 8-oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Dog & Cat Skin Spray, 8-oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Dog & Cat Skin Spray, 8-oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Dog & Cat Skin Spray, 8-oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Dog & Cat Skin Spray, 8-oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Dog & Cat Skin Spray, 8-oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Dog & Cat Skin Spray, 8-oz bottle
Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Dog & Cat Skin Spray, 8-oz bottle

Vetnique Labs Dermabliss Medicated Anti-Bacterial & Anti-Fungal Chlorhexidine Infection Dog & Cat Skin Spray, 8-oz bottle

Rated 4.5 out of 5 stars
357
$16.99Chewy Price
($2.13/oz)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Active Ingredients

4.4/5
Great

Application Method

4.5/5
Great

Effectiveness

4.5/5
Great

Long-Term Results

4.4/5
Great

Is this anti-itch treatment right for my pet?

Breed Size

Small Breeds, Medium Breeds, Large Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Active Ingredients: Chlorhexidine Gluconate 2%, Ketoconazole 1% Inactive Ingredients: Water, Glycerin, Propylene Glycol, Polysorbate 20

Health Feature

Skin & Coat Health
10
Dr. Maggie by NaturPet Inc. Skin Care Ointment Wound Care & Pet First Aid for Cats & Dogs, 30-g tube
Dr. Maggie by NaturPet Inc. Skin Care Ointment Wound Care & Pet First Aid for Cats & Dogs, 30-g tube
Dr. Maggie by NaturPet Inc. Skin Care Ointment Wound Care & Pet First Aid for Cats & Dogs, 30-g tube
Dr. Maggie by NaturPet Inc. Skin Care Ointment Wound Care & Pet First Aid for Cats & Dogs, 30-g tube
Dr. Maggie by NaturPet Inc. Skin Care Ointment Wound Care & Pet First Aid for Cats & Dogs, 30-g tube
Dr. Maggie by NaturPet Inc. Skin Care Ointment Wound Care & Pet First Aid for Cats & Dogs, 30-g tube

Dr. Maggie by NaturPet Inc. Skin Care Ointment Wound Care & Pet First Aid for Cats & Dogs, 30-g tube

Rated 4.3 out of 5 stars
125
$20.99Chewy Price
($0.70/g)
Promo, Spend $100, Get $30 eGift Card with code HAVEFUN

Our ratings

Active Ingredients

4.3/5
Great

Application Method

4.4/5
Great

Effectiveness

4.4/5
Great

Long-Term Results

4.2/5
Great

Is this anti-itch treatment right for my pet?

Breed Size

All Breeds

Lifestage

All Lifestages, Adult

Top Ingredients

Coconut Oil, Caster Oil, Carnauba Wax, Evening Primrose Oil, Borage Seed Oil

Health Feature

First Aid, Sensitive Skin, Anti-Fungal / Anti-Bacterial