Douxo S3 PYO Antiseptic Antifungal Chlorhexidine Dog Mousse, 5.1-oz bottle

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About This Item

Details

  • Mousse soothes, cleans and strengthens irritated skin for dogs.
  • Formulated with ophytrium, a natural ingredient that helps strengthen the skin’s physical barrier.
  • Helps restore the balance of protective microbes.
  • Made without soaps or sulfates.
  • Free of parabens, dyes and nanoparticles.

Ingredients

Instructions

Dermatological Treatment for Skin Issues

Developed with veterinary dermatologists, Douxo S3 offers expert solutions for pets with skin issues. The range includes shampoos, mousses, and pads—designed for daily use and to meet specific skin needs.

Made to Manage Common Skin Conditions

Douxo S3 is made to help manage common skin conditions like allergies, yeast or bacterial overgrowth, and seborrhea. Free from sulfates, parabens, colorants, and silicones, it’s pH-adjusted, soap-free, and hypoallergenic.

Featuring High-Performing Ingredients

 All Douxo S3 formulas contain Ophytrium, a natural-origin, triple-action ingredient that soothes, rebalances and strengthens the skin barrier. Other high-quality ingredients are selected to provide specific benefits in each formula. 

Easy Care for Pleasant Moments

Douxo S3 is designed to make every routine more pleasant for pets and people, with delightful textures and scents and ergonomic packaging. Co-developed with pet parents, it offers a complete skincare solution that’s easy and enjoyable to use.

About Douxo

Backed by 20+ years of expertise in veterinary dermatology, Douxo is designed to make grooming a better experience for both you and your pets.            

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Compare Similar Items

Douxo S3
PYO Antiseptic Antifungal Chlorhexidine Dog Mousse, 5.1-oz bottle
Douxo S3
PYO Antiseptic Antifungal Chlorhexidine Dog Mousse, 5.1-oz bottle
$25.99 Chewy Price
($5.10/oz)
Rated 4.7 out of 5 stars
1.5KReviews
Ingredients           
Ophytrium, Chlorhexidine
Active Ingredients: Ophytrium 0.75%, Inactive Ingredients: Water, capryl/capramidopropyl betaine, phenoxyethanol, pentavitin, panthenol, niacinamide,
Ophytrium, Seboliance
Deionized Water, Vermented Vegetable Extract, Vegetable Extract, Glycerin, rosemary extract, Aloe Vera Gel, Polysorbate 20, SD alcohol, Vitamin E,
Purified Water, Renewable Plant & Coconut-Derived Conditioner & Detangler, Colloidal Oatmeal, Vitamin E, Organic Aloe Vera, Panthenol, Rosemary Oil,
Deionized Water, Stearylkonium Chloride, Hexadecanol, Ethosylated Lanolin, Aloe Vera, Jojoba Oil, Mineral Oil, Glycerin, Vanilla Bean
Grapeseed Oil, Amino Acids, BHA, Natural Keratin, Organic Calcium, Safflower Oil, Wheat Germ Oil, Vitamin A, Vitamin D, Sesame Oil, Vitamin B-5,
SD Alcohol 40, Deioniozed Water, Fragrance, Butylene Glycol, Glycerin
Pramoxine Hydrochloride 1%.
Hydrocortisone 0.5%, Aloe Vera, Benzoic Acid, Benzyl Alcohol, Dipropylene Glycol, Glucose Oxidase, Glycerin, Isopropyl Myristate, Lactoferrin,
Purified Water, SDA 40B Alcohol, Polysorbate 80, Polyquaternium-7 (Conditioner), Glycerin (Moisturizer), Fragrance, Kathon CG (Preservative).
Purified Water, SDA 40B Alcohol, Nonoxynol 9, Polyquaternium-7 (Conditioner), Glycerin (Moisturizer), Fragrance, Kathon CG (Preservative).
Health Feature           
Anti-Fungal / Anti-Bacterial
Itch & Redness Remedy
Odor Control
Skin & Coat Health
Odor Control
Shedding Control, Skin & Coat Health
Paw Care
Odor Control
Itch & Redness Remedy, Skin & Coat Health
Itch & Redness Remedy, Skin & Coat Health
Odor Control
Odor Control
Breed Size           
All Breeds
All Breeds
All Breeds
All Breeds
All Breeds
All Breeds
All Breeds
All Breeds
All Breeds
All Breeds
All Breeds
Grooming Feature           
Medicated
Medicated
Medicated
Deodorizing
Deodorizing, Cruelty-Free
Detangling
Cruelty-Free
Deodorizing, Cruelty-Free
Medicated
Deodorizing

Questions & Answers

21 Customer Questions


Can I use this after conditioner?


what will happen if my dog licks it off? Is it harmful to her? She licks the salve off when I put that on her paws so I have a feeling she’ll like this off to.

Answer by ChewyAug 04, 2021
The Douxo products are non-toxic. If the product is ingested it can have a bad taste to it, so you may see a taste reaction due to that.

Can I use on cat?

Answer by ChewyMay 04, 2022
This mousse is designed for use on dogs only.

How often do you apply this? Daily?

Answer by ChewyJul 28, 2021
This mousse should be used as directed by your veterinarian, as needs will vary by individual pet. The mousse can be used on the entire body or applied on small (localized) areas such as skin folds, paws, etc.

4.7
Rated 4.7 out of 5 stars
1548 Ratings

Customers Mention

Chewy identifies key considerations with the help of artificial intelligence and our veterinarians.

Ease of Use

90% Positive

Effectiveness

91% Positive

Ingredients

91% Positive

Long-Term Benefits

91% Positive

486 Customer Reviews



Rated 5 out of 5 stars
By Mari on Aug 30, 2025
Top 500 Contributor

It’s really work wonder .

My dog got red patchy round thing over her belly. Was not sure but I felt it’s kind of infection from grass or sand from beach. I did try anti bacterial wipe at

My dog got red patchy round thing over her belly. Was not sure but I felt it’s kind of infection from grass or sand from beach. I did try anti bacterial wipe at first . It’s worked well so I got same ingredients . I used this brand with round wipe before however this form is works well Then it for bigger area. Not much works with itchy from allergy.


Rated 5 out of 5 stars
By Robert on Sep 28, 2025

Hands down the best medicated shampoo I’ve ever used for my dog

My pup pad skin issues where she had these open sores all over her body mostly on her belly and her private parts. I did twoshowers per week for two weeks and now

My pup pad skin issues where she had these open sores all over her body mostly on her belly and her private parts. I did twoshowers per week for two weeks and now I’m down to about one shower a week


Rated 5 out of 5 stars
By Jennifer on Aug 19, 2025

Love this arudd

My ECGR has some sort of allergies, mainly affects her ears and her feet. She looks her feet obsessively and our veterinarian recommended this to put on herfeet

My ECGR has some sort of allergies, mainly affects her ears and her feet. She looks her feet obsessively and our veterinarian recommended this to put on herfeet when she’s done playing in the yard. It smells good and apparently it taste good because she loves to lick it off. Hopefully the more I consistently use it it will work.


Rated 5 out of 5 stars
By Sasha on Jul 26, 2025

Bye-bye itchy paws!

I have a German Shepherd with allergies. He digs and itches his paws frequently and the vet suggested we give this a try. What a game changer! It's not immediate

I have a German Shepherd with allergies. He digs and itches his paws frequently and the vet suggested we give this a try. What a game changer! It's not immediate relief, they will still be itchy, but I did notice the itching decreased within 24 hours. After a few weeks, the redness and itching was completely gone. I do want to add, he is prone to allergies, so even though the itching is gone for a while with this, it does return. When it does, back to this we go!


Rated 5 out of 5 stars
By Kody1 on Jul 24, 2025

Vet Recommended

The shampoo was recommended by my Vet but the mousse works wonders also. My girl has skin allergies and after playing in the controlled yard area I shampoo all

The shampoo was recommended by my Vet but the mousse works wonders also. My girl has skin allergies and after playing in the controlled yard area I shampoo all the areas that were exposed. She wears a tshirt to protect her skin. She gets a rash under her arms, legs, tail and redness in paws. I shampoo those areas and afterwards use the mousse especially in her paws and it takes care of the redness. Actually, i don't have to give her the cytopoint injections anymore!


Rated 5 out of 5 stars
By Nicole on Oct 4, 2025

Easy to apply and smells good.

My vet recommended this for some fall allergies my dog is experiencing, and it does seem to have a soothing effect for her in the affected areas of her skin.

My vet recommended this for some fall allergies my dog is experiencing, and it does seem to have a soothing effect for her in the affected areas of her skin.


Rated 5 out of 5 stars
By Rachel on Sep 20, 2025

Great!

I first got this from my vet when my cat licked her paw raw from anxiety. It worked so well that now I keep buying it whenever she has an episode. Really helps and

I first got this from my vet when my cat licked her paw raw from anxiety. It worked so well that now I keep buying it whenever she has an episode. Really helps and very effective!


Rated 1 out of 5 stars
By Valerie on Sep 11, 2025

Paw chewing

I was disappointed with this one. They told me it would stop the chewing on his paws and it hasn’t. My doggie is still biting and chewing his paws. I’ve put it on

I was disappointed with this one. They told me it would stop the chewing on his paws and it hasn’t. My doggie is still biting and chewing his paws. I’ve put it on several times a day and nothing.


Rated 5 out of 5 stars
By Mary Beth on Aug 19, 2025
Top 1000 Contibutor

Amazing

My goldendoodle was suffering from yeast infections on her legs/arm pits. She constantly itched and licked this area which turned her skin and fur red...after one

My goldendoodle was suffering from yeast infections on her legs/arm pits. She constantly itched and licked this area which turned her skin and fur red...after one use the irritation and discovered fur was gone!!


Rated 5 out of 5 stars
By Dwight on Jul 29, 2025

Great on our dogs paws

We use this in our labs paws. Put it on every other day or anytime paws get wet. Foot chewing has stopped and frito smell is gone. Just rub it down between the

We use this in our labs paws. Put it on every other day or anytime paws get wet. Foot chewing has stopped and frito smell is gone. Just rub it down between the toes and around the nails. Started on a recommendation from our vet and it worked so well we kept using it.