How does dog oral flea medicine work?

Oral flea medicine for dogs works by entering your pet’s bloodstream after ingestion, killing fleas when they feed on your pet. The medicine usually contains a chemical that adversely affects the insect’s nervous system without harming your pet. Oral flea medicines usually act mainly on adult fleas, but some have an insect growth regulator that helps prevent re-infestation, as well.

What is the best oral flea treatment for dogs?

The best oral flea treatment for dogs will both kill fleas and ticks on contact and provide long-term protection against flea re-infestation. Look for products that combine adult flea and tick control with a hormone growth regulator that will prevent flea eggs and larvae from maturing. This will help break the flea lifecycle and protect your pet and your home from recurring flea issues.

How long do dog flea pills take to work?

Dog flea pills can take as little as 30 minutes to work, killing biting fleas as soon as it gets into your pet’s bloodstream. Killing all the fleas on your pet may take 24 hours or more, and you may see itching for several days afterward as new fleas hatch and jump on to bite. Eradicating a flea infestation completely can take time, so be sure to use a long-acting flea preventative to prevent a resurgence and administer as directed on the package.

How long does dog oral flea treatment usually last?

Oral flea treatment can last for as long as a month or as little as 24 hours. The duration of flea control action will vary depending on which treatment you choose. Some dog flea pills and chews are designed to kill fleas on your pet and then stop working. Others provide continuous protection for 30 days, killing fleas whenever they bite. For continuous flea protection, monthly oral treatments with insect growth regulators are widely considered the best.

Flea & Tick Pills for Dogs - Page 2 (Free Shipping)

37 - 72 of 72 Results

Sort by

More Choices Available

Sentinel Spectrum Chew for Dogs, 8.1-25 lbs, (Green Box), 6 Chews (6-mos. supply)

Rated 4.4867 out of 5 stars

113

$53.99Chewy Price

FREE shipping on this item

Prescription Item

Bundle: Capstar Flea Oral Treatment for Dogs, over 25 lbs, 6 Tablets + Onguard Flea & Tick Spot...

$72.46Chewy Price

$76.27List Price

$68.84Autoship Price

Spend $100, Get $30 eGift Card With Code: SPRING

FREE 1-3 day shipping on this item

Deal

PetTest Methyl B-12 Roasted Turkey Flavor Cat & Dog Oral Treatment, 4-oz bottle

$59.95Chewy Price

$56.95Autoship Price

Spend $100, Get $30 eGift Card With Code: SPRING

FREE 1-3 day shipping on this item

More Choices Available

Comfortis Chewable Tablet for Dogs, 5-10 lbs & Cats 4.1-6 lbs, (Pink Box), 6 Chewable Tablets (...

Rated 4.8889 out of 5 stars

$108.99Chewy Price

$103.54Autoship Price

FREE shipping on this item

Prescription Item

More Choices Available

Sentinel Tablet for Dogs, 51-100 lbs, (White Box), 6 Tablets (6-mos. supply)

Rated 4.6202 out of 5 stars

208

$72.99Chewy Price

FREE shipping on this item

Prescription Item

More Choices Available

Simparica Chewable Tablet for Dogs, 88.1-132 lbs, (Brown Box), 6 Chewable Tablets (6-mos. suppl...

Rated 4.3158 out of 5 stars

$120.99Chewy Price

$114.94Autoship Price

FREE shipping on this item

Prescription Item

Bundle: Capstar Flea Oral Treatment for Dogs, 2-25 lbs, 6 Tablets + Elanco Tapeworm Dog De-Worm...

$61.25Chewy Price

$64.48List Price

Spend $100, Get $30 eGift Card With Code: SPRING

FREE 1-3 day shipping on this item

More Choices Available

Bravecto Chew for Dogs, 4.4-9.9 lbs, (Yellow Box), 1 Chew (12-wks. supply)

Rated 4.6032 out of 5 stars

126

$67.99Chewy Price

FREE shipping on this item

Prescription Item

More Choices Available

Trifexis Chewable Tablet for Dogs, 20.1-40 lbs, (Green Box), 6 Chewable Tablets (6-mos. supply)...

Rated 4.4471 out of 5 stars

208

$132.42Chewy Price

$125.80Autoship Price

FREE shipping on this item

Prescription Item

More Choices Available

Simparica Trio Chewable Tablet for Dogs, 5.6-11.0 lbs, (Purple Box), 6 Chewable Tablets (6-mos....

Rated 4.3929 out of 5 stars

112

$159.99Chewy Price

$151.99Autoship Price

Save 50% on First Autoship

FREE shipping on this item

Prescription Item

Deal

NaturPet D Wormer Natural Remedy for Cats & Dogs, 100-ml bottle

Rated 2.375 out of 5 stars

$19.99Chewy Price

$18.99Autoship Price

Spend $100, Get $30 eGift Card With Code: SPRING

FREE 1-3 day shipping over $49

More Choices Available

Advantus Flea Oral Treatment for Dogs, 4-22 lbs, 30 Soft Chews

Rated 3.5816 out of 5 stars

$56.98Chewy Price

$59.98List Price

$54.13Autoship Price

FREE 1-3 day shipping on this item

Bundle: Capstar Flea Oral Treatment for Dogs, 2-25 lbs, 6 Tablets + Onguard Flea & Tick Spot Tr...

Rated 1 out of 5 stars

$70.73Chewy Price

$74.46List Price

$67.19Autoship Price

Spend $100, Get $30 eGift Card With Code: SPRING

FREE 1-3 day shipping on this item

More Choices Available

Credelio Chewable Tablet for Dogs, 6.1-12 lbs, (Pink Box), 1 Chewable Tablet (1-mo. supply)

Rated 4.561 out of 5 stars

$22.99Chewy Price

$21.84Autoship Price

FREE shipping over $49

Prescription Item

More Choices Available

Comfortis Chewable Tablet for Dogs 40.1-60 lbs (Blue Box), 6 Chewable Tablets (6-mos. supply)

Rated 4.6842 out of 5 stars

$119.99Chewy Price

$113.99Autoship Price

FREE shipping on this item

Prescription Item

More Choices Available

Sentinel Tablet for Dogs, 2-10 lbs, (Brown Box), 6 Tablets (6-mos. supply)

Rated 4.726 out of 5 stars

$48.99Chewy Price

FREE shipping over $49

Prescription Item

More Choices Available

Simparica Chewable Tablet for Dogs, 5.6-11 lbs, (Purple Box), 6 Chewable Tablets (6-mos. supply...

Rated 4.625 out of 5 stars

$104.99Chewy Price

$99.74Autoship Price

FREE shipping on this item

Prescription Item

Deal

PetAlive Parasite Dr. Homeopathic Medicine for Cats & Dogs, 60 count

Rated 2.3333 out of 5 stars

$39.95Chewy Price

$37.95Autoship Price

Spend $100, Get $30 eGift Card With Code: SPRING

FREE 1-3 day shipping over $49

Bravecto 1-Month Chew for Dogs, 22-44 lbs, (Green Box), 1 Chew (1-mo. supply)

Rated 4.8333 out of 5 stars

$22.99Chewy Price

FREE shipping over $49

Prescription Item

More Choices Available

Trifexis Chewable Tablet for Dogs, 40.1-60 lbs, (Blue Box), 6 Chewable Tablets (6-mos. supply)

Rated 4.3824 out of 5 stars

204

$139.04Chewy Price

$132.09Autoship Price

FREE shipping on this item

Prescription Item

More Choices Available

Simparica Trio Chewable Tablet for Dogs, 2.8-5.5 lbs, (Gold Box), 6 Chewable Tablets (6-mos. su...

Rated 3.75 out of 5 stars

$156.99Chewy Price

$149.14Autoship Price

Save 50% on First Autoship

FREE shipping on this item

Prescription Item

More Choices Available

Sentinel Spectrum Chew for Dogs, 25.1-50 lbs, (Yellow Box), 6 Chews (6-mos. supply)

Rated 4.4242 out of 5 stars

$64.99Chewy Price

FREE shipping on this item

Prescription Item

Bundle: Capstar Flea Oral Treatment for Dogs, 2-25 lbs, 6 Tablets + Vet's Best Flea + Tick Yard...

Rated 3 out of 5 stars

$47.61Chewy Price

$50.12List Price

$45.23Autoship Price

Spend $100, Get $30 eGift Card With Code: SPRING

FREE 1-3 day shipping over $49

Bundle: Capstar Flea Oral Treatment for Dogs, over 25 lbs, 6 Tablets + Onguard Flea & Tick Spot...

Rated 3.6667 out of 5 stars

$69.30Chewy Price

$72.95List Price

$65.84Autoship Price

Spend $100, Get $30 eGift Card With Code: SPRING

FREE 1-3 day shipping on this item

Bravecto 1-Month Chew for Dogs, 9.9-22 lbs, (Orange Box), 1 Chew (1-mo. supply)

Rated 4 out of 5 stars

$21.99Chewy Price

FREE shipping over $49

Prescription Item

More Choices Available

Comfortis Chewable Tablet for Dogs, 10.1-20 lbs, & Cats, 6.1-12 lbs, (Orange Box), 6 Chewable T...

Rated 4.2313 out of 5 stars

147

$108.99Chewy Price

$103.54Autoship Price

FREE shipping on this item

Prescription Item

More Choices Available

Comfortis Chewable Tablet for Dogs, 20.1-40 lbs & Cats 12.1-24 lbs, (Green Box), 6 Chewable Tab...

Rated 4 out of 5 stars

$112.99Chewy Price

$107.34Autoship Price

FREE shipping on this item

Prescription Item

More Choices Available

Simparica Chewable Tablet for Dogs, 2.8-5.5 lbs, (Yellow Box), 6 Chewable Tablets (6-mos. suppl...

Rated 4.4167 out of 5 stars

$102.99Chewy Price

$97.84Autoship Price

FREE shipping on this item

Prescription Item

More Choices Available

Trifexis Chewable Tablet for Dogs, 5-10 lbs, (Magenta Box), 6 Chewable Tablets (6-mos. supply)

Rated 4.5472 out of 5 stars

106

$122.68Chewy Price

$116.55Autoship Price

FREE shipping on this item

Prescription Item

Bravecto 1-Month Chew for Dogs, 4.4-9.9 lbs, (Yellow Box), 1 Chew (1-mo. supply)

Rated 4.6667 out of 5 stars

$21.99Chewy Price

FREE shipping over $49

Prescription Item

More Choices Available

Credelio Chewable Tablet for Dogs, 4.4-6 lbs, (Yellow Box), 1 Chewable Tablet (1-mo. supply)

Rated 5 out of 5 stars

$22.99Chewy Price

$21.84Autoship Price

FREE shipping over $49

Prescription Item

More Choices Available

Sentinel Spectrum Chew for Dogs, 2-8 lbs, (Orange Box), 6 Chews (6-mos. supply)

Rated 4.2187 out of 5 stars

$51.99Chewy Price

FREE shipping on this item

Prescription Item

Out of Stock

Your cart is empty.

Flea & Tick Pills for Dogs

Breed Size

Medication Type

Kills or Treats

Brand

Repels or Prevents

Shop Conscious

Deals & Savings

Price

Customer Rating