Out of Stock Tri-Otic (Gentamicin / Betamethasone / Clotrimazole) Otic Ointment for Dogs, slide 1 of 1

Tri-Otic (Gentamicin / Betamethasone / Clotrimazole) Otic Ointment for Dogs

Prescription Item

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Strength: 25-g
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Tri-Otic ointment is a prescription medication used to treat acute and chronic external ear infections, caused by bacteria and yeast. It also reduces inflammation, pain and itching, while it reduces ear wax production. This safe, effective formula comes as an ointment to be placed easily in the ears.

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Tri-Otic is used to treat ear infections caused by bacteria and yeast. It also reduces inflammation, pain and itching, plus it reduces ear wax production.

Possible Side Effects

Please contact your veterinarian immediately if you notice any of the following reactions: loss of hearing or balance, increase in the amount of drinking and urinating, facial swelling, hives, scratching, a sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs or coma. Less common side effects are increased appetite and weight gain, panting, diarrhea, vomiting and behavior changes. If given at high doses or for extended periods, may cause delayed wound healing and immunosuppression resulting in an increased risk of bacterial or fungal infections. Other side effects are possible.

Drug & Food Interactions

Notify your veterinarian of any other medications, including vitamins and supplements, your pet is taking before using this medication. Make sure your pet does not ingest the medication. If ingested at high doses or for extended periods, it can cause premature birth especially toward the end of pregnancy. It may also cause birth defects in some animals. Other drug interactions may occur.


Do not use in pets who are allergic to any of the ingredients, have a perforated eardrum or require hearing to perform their work, as there may be hearing or vestibular (balance) impairment.

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  1. Prescribing Information

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  • Item Number
  • Common Brand Name(s)
  • For Use With
  • Generic Name
    Gentamicin Sulfate, Betamethasone Valerate, Clotrimazole
  • Administration Form
  • Product Form
  • Health Condition
    Ear Infections
  • Drug Type
    Antibiotic, Antifungal, Anti-inflammatory

Active Ingredients: Gentamicin Sulfate, USP equivalent to 3 mg Gentamicin base; Betamethasone Valerate, USP equivalent to 1 mg Betamethasone; and 10 mg Clotrimazole, USP.

Inactive Ingredients: Mineral oil-based system containing a plasticized Hydrocarbon gel.

Recommended Dosage

Instill two drops twice daily into the ear canal of pets weighing less than 30 lbs. Instill four drops twice daily into the ear canal of pets weighing 30 lbs or more.

Storage Instructions

Store between 36° - 77°F. Shake well before use.


What is Tri-Otic Ointment?

This medication treats canine ear infections caused by bacteria and yeast. It also reduces inflammation, pain, and itching and reduces ear wax production. It includes 3 active ingredients - betamethasone valerate, gentamicin sulfate, and clotrimazole that are a triple combination of steroid, antibacterial, and antifungal treatments.

What are the benefits of Tri-Otic Ointment?

  • Combination medication for the treatment of acute and chronic otitis (ear infection).
  • Convenient applicator makes administration easy.
  • Effective against inflammation, bacterial, and yeast infections of the ear.

How is this medication given?

Follow treatment instructions carefully, since incorrect treatment can result in recurring infections and damage to the ear. The external ear should be clean and dry before application. Excessive hair should be trimmed from the treatment area. Apply the prescribed amount of this topical ointment in the ear and gently massage the ear to distribute the medication. Always follow the dosage instructions provided by your veterinarian.

How does this medication work?

This medication treats acute and chronic otitis (ear infection) with gentamicin (an antibiotic) and betamethasone (a corticosteroid). This combination is approved for the treatment of inflammation and bacterial infections of the ear. Also contains clotrimazole, for the effective treatment of fungal (yeast) infections of the ear.

What results can I expect?

Tri-Otic Ointment will help to relieve the symptoms and kill the organisms causing ear infections. This medication is not labeled for use beyond 7 days since it could delay wound healing. If symptoms persist after the end of the treatment period, contact your veterinarian.

Rating: 5.0 of 5 stars 2 Reviews 2 Reviews 5 out of 5 Stars

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  • 5 out of 5 stars

    Works Great For Us

    By MandyA on Nov 5, 2018

    We use this product to help prevent ear infections and it has worked like a charm! We use it under the guidance of our vet as we had a previous dog prone to infections and want to avoid them for our current pup. We have always had wonderful results from this product and are so glad to see it on Chewy!

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  • 5 out of 5 stars

    Excellent option for Otomax

    By catwoman0129 on Sep 19, 2018

    Otomax has gotten so expensive (what hasn't?) that I was very pleased to find this generic option at a MUCH less expensive price. Very pleased with my choice!

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